Niigata-shi, Niigata, Japan

  • Strategic Screening for Infectious Diseases (Tuberculosis, HIV, HBV, HCV) Amongst Migrants in France

    In France, the prevalence of infectious diseases such as tuberculosis, HIV/HBV/HCV is high amongst migrants originating from certain countries, hence the official guidelines recommending targeted testing. The rapid testing devices (TROD) give immediate results and reduce missed opportunities. However their use is not yet widespread and migrant populations remain insufficiently tested. Regarding the UNAIDS 90-90-90 goal, France is failing the screening part of the treatment cascade, while 90% of patients are treated and have undetectable viral load. Risk scores based on the best known risk factors for these infections (HIV/HBV/HCV) have previously been developed. They have helped build a pilot of a new unique questionnaire: TROD screen. An electronic survey, called TB screen, was designed to screen for tuberculosis amongst asylum seekers in Switzerland and validated. This survey enables to detect signs of active tuberculosis and may replace the use of pulmonary radiography, thus reducing exposure to X-rays. It is a prospective multi-centric observational study validating screening tests for HIV/HBV/HCV in two phases: - Phase 1: a risk score will be validated, including a qualitative study analyzing its acceptability - Phase 2: its performance will be compared with that of a screening targeted based on the country of origin The phase 1 and phase 2 will include respectively 10.000 and 5000 participants. For tuberculosis, the efficacy of the improved version of TB screen will be compared with a systematic radiography. Participation to this study will be voluntary and independent from the delivery of a residence permit. Participants will be informed of it and will systematically receive information about prevention of those infectious diseases.

    Phase

    N/A

    Span

    120 weeks

    Sponsor

    University Paris 7 - Denis Diderot

    Montrouge

    Recruiting

    Healthy Volunteers

  • Optimizing Bronchopulmonary Cancer Screening

    The organization of bronchopulmonary cancer screening in the Ile de France region, within the Mutualists and its affiliated health centers, is based on a clear, simple and functional process: - Definition of eligibility criteria for screening, based on those of the NELSON study, - Referral and consultation by a health center physician trained in these criteria, - Referral and performance of a chest Computer Tomography Scanner (CTscan) according to the same recommendations, - Structured centralized reading and interpretation of CTscan images, - Referral to a multidisciplinary team (CITT), if bronchopulmonary cancer is suspected, - Referral to a tobacco unit in a health center for smokers who have not stopped smoking, - Organization of follow-up and continuation of the screening program.

    Phase

    N/A

    Span

    418 weeks

    Sponsor

    Institut Curie

    Malakoff

    Recruiting

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