Nerima-ku, Japan Clinical Trials

A listing of Nerima-ku, Japan clinical trials actively recruiting patients volunteers.

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Found 20 clinical trials
ADCC Mediated B-Cell dEpletion and BAFF-R Blockade

VAY736 dose testing; VAY736 efficacy and safety testing.

adcc
Novartis Investigative Site
 (3.9 away) Contact site
  • 83 views
  • 14 Jun, 2021
  • +58 other locations
Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy

The primary objectives of this study are to examine the clinical efficacy of nusinersen administered intrathecally at higher doses to participants with SMA, as measured by change in Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP INTEND) total score (Part B); to examine the safety and tolerability of …

muscle atrophy
nusinersen
gene deletion
Tokyo Women's Medical University Hospital
 (4.6 away) Contact site
  • 42 views
  • 03 Jun, 2021
  • +46 other locations
Trial of Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma

The purpose of this study is to compare the efficacy and safety of cisplatin (CDDP) and epirubicin (EPI) in the treatment of transcatheter chemoembolization for Hepatocellular Carcinoma (HCC).

TACE
hepatoma
transcatheter arterial chemoembolisation
chemoembolization
Department of Digestive Surgery, Nihon University School of Medicine
 (2.4 away) Contact site
  • 4 views
  • 07 Nov, 2020
  • 1 location
Long-Term Follow-up Protocol for Subjects Treated With Gene-Modified T Cells

This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult subjects exposed to Gene-modified (GM) T cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study. Subjects who received at least one GM T cell infusion, will …

treatment regimen
Tokyo Women's Medical University Hospital
 (4.6 away) Contact site
  • 153 views
  • 21 Feb, 2021
  • +186 other locations
Efficacy & Safety of TD-1473 in Ulcerative Colitis

A Phase 2b/3 set of studies to evaluate the efficacy and safety of induction and maintenance therapy with TD-1473 in subjects with moderately-to-severely active ulcerative colitis with up to 60 weeks of treatment.

corticosteroids
immunomodulators
aminosalicylates
Theravance Biopharma Investigational Site
 (10.0 away) Contact site
  • 75 views
  • 28 Jan, 2021
  • +202 other locations
A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 and GALAXI 3) and safety of guselkumab in participants with Crohn's disease.

endoscopy
ileitis
colitis
abdominal pain
crohn's disease
Tokyo Yamate Medical Center
 (3.4 away) Contact site
  • 792 views
  • 18 Jun, 2021
  • +796 other locations
A Multicenter Randomized Double-Blind Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the appropriate induction dose of risankizumab for further evaluation in Sub-Study 2. The objective of Sub-Study 2 is to …

remission
Teikyo University Hospital /ID# 225588
 (3.9 away) Contact site
  • 604 views
  • 16 Jun, 2021
  • +772 other locations
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with moderately to severely active ulcerative colitis (UC).

medical therapy
Tokyo Yamate Medical Center
 (3.4 away) Contact site
  • 226 views
  • 16 Jun, 2021
  • +519 other locations
Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L Biliary Tract Cancer (BTC)

Study consists of an open-label, safety run-in part and a randomized, double-blind, placebo-controlled Phase 2/3 part. In the Phase 2/3 part, the study will evaluate whether bintrafusp alfa in combination with the current standard of care (SoC) (gemcitabine plus cisplatin) improves overall survival (OS) in chemotherapy and immunotherapy-nave participants with …

kidney function tests
measurable disease
gemcitabine/cisplatin
antivirals
renal function
Kyorin University Hospital
 (6.2 away) Contact site
  • 173 views
  • 05 May, 2021
  • +125 other locations
Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease

The primary objective of the study is to determine if treatment with high-dose aflibercept (HD) at intervals of 12 or 16 weeks provides non-inferior best corrected visual acuity (BCVA) compared to aflibercept dosed every 8 weeks. The secondary objectives of the study are as follows: To determine the effect of …

retinopathy
diabetic eye disease
diabetic macular edema
swelling
aflibercept
Regeneron Study Site
 (3.1 away) Contact site
  • 17 views
  • 14 May, 2021
  • +199 other locations