Nerima-ku, Japan Clinical Trials

A listing of Nerima-ku, Japan clinical trials actively recruiting patients volunteers.

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Found 72 clinical trials
Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung02)

This study will assess safety and treatment activity of datopotamab deruxtecan (Dato-DXd) in combination with pembrolizumab with or without platinum chemotherapy in participants with advanced or metastatic non-small cell lung cancer.

National Cancer Center Hospital
 (8.3 away) Contact site
  • 12 views
  • 27 May, 2021
  • +22 other locations
First In Human Study With ABBV-CLS-579 When Given Alone Or In Combination With Programmed Cell Death-1 Inhibitor In Participants With Locally Advanced Or Metastatic Tumors

The purpose of this study is to see how safe and effective ABBV-CLS-579 is when used alone or in combination with programmed cell death protein-1 (PD-1) inhibitors in treating solid cancers. ABBV-CLS-579 is an investigational drug being developed for the treatment of solid tumors. The study has two arms - …

National Cancer Center Hospital
 (8.3 away) Contact site
  • 5 views
  • 18 Apr, 2021
  • +7 other locations
Study to Determine the Safety Tolerability Pharmacokinetics and RP2D of ABBV-151 as a Single Agent and in Combination With ABBV-181 in Participants With Locally Advanced or Metastatic Solid Tumors

The study will determine the recommended Phase 2 dose (RP2D) of ABBV-151 administered as monotherapy and in combination with budigalimab (ABBV-181) as well as to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-151 alone and in combination with budigalimab. The study will consist of 2 phases: dose escalation …

National Cancer Center Hospital /ID# 209421
 (8.3 away) Contact site
  • 17 views
  • 31 May, 2021
  • +37 other locations
A Study of ASP1948 Targeting an Immune Modulatory Receptor as a Single Agent and in Combination With a PD-l Inhibitor (Nivolumab or Pembrolizumab) in Subjects With Advanced Solid Tumors

The purpose of this study is to evaluate the tolerability and safety profile of ASP1948 when administered as a single agent and in combination with nivolumab or pembrolizumab in participants with locally advanced (unresectable) or metastatic solid tumors; characterize the pharmacokinetic profile of ASP1948 when administered as a single agent …

Site JP81001
 (4.1 away) Contact site
  • 75 views
  • 02 Jun, 2021
  • +55 other locations
A Study of Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung Cancer

The purpose of this study is to confirm the tolerability of recommended Phase 2 dose (RP2D) of Lazertinib (Phase 1), to determine the tolerability and identify the recommended Phase 2 combination dose of Lazertinib when combined with Amivantamab (Phase 1b), to characterize the safety and tolerability of Lazertinib and Amivantamab …

growth factor
afatinib
kinase inhibitor
platinum-based chemotherapy
erlotinib
National Cancer Center Hospital
 (8.3 away) Contact site
  • 5 views
  • 13 Jun, 2021
  • +86 other locations
Study of AMG 199 in Subjects With MUC17-Positive Gastric and Gastroesophageal Junction Cancer

To evaluate the safety and tolerability of AMG 199 in adult subjects with MUC17-positive gastric and gastroesophageal junction cancer and to determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D).

Research Site
 (8.3 away) Contact site
  • 7 views
  • 13 Jun, 2021
  • +38 other locations
A Study to Evaluate Next Day Effects of TS-142 on Driving Performance in Healthy Subjects

A clinical study to evaluate the residual effects of TS-142 on driving performance in healthy and elderly subjects.

Taisho Pharmaceutical Co., Ltd selected site
 (4.1 away) Contact site
  • 0 views
  • 03 Feb, 2021
  • 1 location
A Study in Healthy Japanese Men to Test How Well Different Doses of BI 764198 Are Tolerated

The main objectives of this trial are to investigate safety and tolerability of BI 764198 in healthy male subjects following oral administration of single dose and multiple rising doses per day over 14 days. Secondary objectives are the exploration of pharmacokinetics (PK) of BI 764198 after single and multiple oral …

SOUSEIKAI Sumida Hospital
 (8.7 away) Contact site
  • 0 views
  • 12 Jun, 2021
  • 1 location
A Study in Healthy Japanese Men to Test How Different Doses of BI 1323495 Are Tolerated and How Itraconazole Influences the Amount of BI 1323495 in the Blood

The main objective of the single-rising dose (SRD) part and the multiple rising dose (MD) part is to investigate safety, tolerability, pharmacokinetics and pharmacodynamics (for MD part only) following single rising doses and multiple oral doses of BI 1323495 in healthy male Japanese subjects genotyped as poor metabolizers (PM) and …

SOUSEIKAI Sumida Hospital
 (8.7 away) Contact site
  • 0 views
  • 12 May, 2021
  • 1 location
Study to Evaluate the Pharmacokinetics (PK) of E7090 and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants

The primary purpose of the study is to evaluate the effects of mild and moderate hepatic impairment on PK of E7090 after a single dose administration.

moderate hepatic insufficiency
e7090
electrocardiogram
body mass index
Eisai Trial Site #3
 (5.9 away) Contact site
  • 406 views
  • 03 Jun, 2021
  • +3 other locations