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Kashiwa-city, Japan Clinical Trials

A listing of Kashiwa-city, Japan clinical trials actively recruiting patients volunteers.

RESULTS

Found (31) clinical trials

A Study of E7130 in Participants With Solid Tumors

The primary objective of this study is to evaluate the tolerability and safety profile of E7130 in participants with advanced solid tumors.

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Evaluation of SAR408701 in Japanese Patients With Advanced Malignant Solid Tumors

The study duration per participant will include a period to assess eligibility (screening period) of up to approximately 4 weeks (28 days), a treatment period and an End-of-Treatment (EOT) visit around 30 days after the last administration of IMP, and at least one follow-up (FU) visit after the EOT visit.

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A Study to Evaluate TAK-931 in Participants With Advanced Nonhematologic Tumors

The drug being under investigation in this study is called TAK-931. The effect of TAK-931 is being evaluated in up to 100 participants who have nonhematologic (solid) neoplasms. This study will look at the safety, tolerability, and PK to determine the maximum tolerated dose (MTD) of TAK-931. This multi-center trial ...

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Special Combination of OBP-301 and Pembrolizumab

Phase 1a part: To evaluate safety and tolerability in combination of OBP-301 and Pembrolizumab in patient with advanced or metastatic solid tumor and to determine recommended dose in phase 1b part. Phase 1b part: To evaluate safety and potential efficacy in combination of OBP-301 and Pembrolizumab in patients in expanded ...

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Study of E7389 Liposomal Formulation in Subjects With Solid Tumor

The maximum tolerated dose (MTD) of E7389 liposomal formulation (E7389-LF) will be determined in the dose escalation part. Safety, pharmacokinetics (PK) and efficacy will be assessed using treatment regimen evaluated in dose escalation part in participants with breast cancer in the expansion part 1 and in participants with adenoid cystic ...

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A Phase 1 Study of TAK-788 in Japanese Patients

The drug being tested in this study is called TAK-788. TAK-788 is being tested to treat Japanese participants with NSCLC. This study will look at the safety, efficacy, tolerability and PK of TAK-788 orally administered once daily, and will determine a RP2D. The study will enroll approximately 28-33 participants. All ...

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A Study of E7386 in Combination With Other Anticancer Drug in Participants With Solid Tumor

The primary objective of this study is to assess the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of E7386 in combination with other anticancer drug(s).

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Evaluation of Orally Administered SAR439859 in Japanese Postmenopausal Patients With Advanced Breast Cancer

The duration of the study for an individual participant will include a period to assess eligibility (screening period) of up to 4 weeks (28 days), a treatment period of at least 1 cycle (28 days) of study treatment, and an End of Treatment (EOT) visit at least 30 days (or ...

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Study Evaluating Safety Tolerability and PK of AMG 757 in Adults With Small Cell Lung Cancer

This is an open-label, ascending, multiple dose, phase 1 study evaluating AMG 757 administered as a short term intravenous (IV) infusion in subjects with small cell lung cancer. AMG 757 is a Half Life Extended (HLE) Bispecific T cell engager (BiTE) targeting delta-like protein 3 (DLL3)

Phase

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A Study to Evaluate the Safety Pharmacokinetics Pharmacodynamics and Immunogenicity of JNJ-63723283 an Anti-Programmed Cell Death (PD)-1 Monoclonal Antibody as Monotherapy or in Combination With Erdafitinib in Japanese Participants With Advanced Solid Cancers

The primary purpose of this study is to identify the recommended Phase 2 dose (RP2D) of JNJ-63723283 as a monotherapy (Phase 1a part) and to identify the RP2D of JNJ-63723283 when administered in combination with Erdafitinib (Phase 1b part).

Phase

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