Hamura,tokyo, Japan
Kaneka Endovascular Embolization and Protection
Assess and describe real world clinical data on i-ED coils Characterize the acute and long-term performance of iED coils when used for treating for an intracranial aneurysm May be used alone or in combination with other adjunctive device(s) Study Duration Anticipated timeline for study: Patient enrollment in 18 - 24 months Completion of follow-up 12 months after last patient enrolled
Phase
N/ASpan
151 weeksSponsor
Kaneka Medical America LLCGrand Blanc, Michigan
Recruiting
A Study to Evaluate Effectiveness and Safety of Deucravacitinib (BMS-986165) Compared With Placebo in Participants With Active Systemic Lupus Erythematosus
Phase
3Span
258 weeksSponsor
Bristol-Myers SquibbGrand Blanc, Michigan
Recruiting
The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)
Phase
2Span
135 weeksSponsor
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, GermanyGrand Blanc, Michigan
Recruiting
Different Doses of Naronapride Vs. Placebo in Gastroparesis
Phase
2Span
157 weeksSponsor
Dr. Falk Pharma GmbHFlint, Michigan
Recruiting
Randomized Trial Comparing Immediate Vs. Deferred Surgery for Symptomatic ERM
Phase
N/ASpan
254 weeksSponsor
Jaeb Center for Health ResearchGrand Blanc, Michigan
Recruiting
Grand Blanc, Michigan
Recruiting
Effect of Early Administration of TXA in Adult Hip Fractures
Phase
2/3Span
44 weeksSponsor
Ascension Genesys HospitalGrand Blanc, Michigan
Recruiting
Healthy Volunteers
Efficacy of Local Anesthetic Through Continuous Infusion
This study will evaluate the benefits of placing an analgesic pain pump in laparotomy incisions with the addition of intravenous/oral pain medications as needed versus using solely intravenous and oral pain medications as needed for post-operative pain management. The goal of this study will be to decrease the usage of narcotics in post-operative laparotomy patients by providing local incision pain relief. This will be a double blinded randomized control study with placebo with two groups of patients: One with a local anesthetic infusion pump filled with Bupivacaine, a local anesthetic, after laparotomy and the other group with an infusion pump filled with normal saline. The pain pumps will be placed in the OR. Post-operatively, all patients will have the standard pain regimen available to them during their stay. Surgeons will monitor the patient for 4 days post-operatively and the infusion pain pump will be removed on post-operative day 4. Investigator will then look back through each patient's records and gather the amount of pain medications that they requested during their stay. Both groups will then have their data collected in the same manner and placed for data analysis. - The standard pain regimen will include a morphine IV 4mg every 4 hours and Hydrocodone-acetominophen 5/325 Q6H PRN. If a patient controlled analgesia infusion pump is needed this will be considered a need for increase in pain management. Every patient will be started on this pain regimen post operatively. During their stay, If the patient requires an increase in their pain medication, the supervising attending will determine which drug will be added in improve their pain. At the end of the patients stay, the amount of narcotic usage will be compiled and turned into morphine equivalents in order to compare them with the control group.
Phase
3Span
156 weeksSponsor
Ascension Genesys HospitalGrand Blanc, Michigan
Recruiting
A Study of Baricitinib in Participants With Rheumatoid Arthritis
Phase
4Span
324 weeksSponsor
Eli Lilly and CompanyGrand Blanc, Michigan
Recruiting
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
Phase
3Span
475 weeksSponsor
Uppsala UniversityGrand Blanc, Michigan
Recruiting