Hachioji, Japan Clinical Trials

A listing of Hachioji, Japan clinical trials actively recruiting patients volunteers.

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Found 87 clinical trials
A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression

This study is open to adults with depression (major depressive disorder) for whom standard treatment with antidepressants alone does not work sufficiently. The purpose of the trial is to find out whether a medicine called BI 1358894 helps to improve symptoms of depression. Four different doses of BI 1358894 are …

National Center Neurology and Psychiatry
 (10.0 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +64 other locations
Study to Gather Information on Safety and Use of High Dose Aflibercept Injection Into the Eye in Patients With an Age Related Eye Disorder That Causes Blurred Vision or a Blind Spot Due to Abnormal Blood Vessels That Leak Fluid Into the Light Sensitive Lining Inside the Eye

In this study researchers want to learn more about changes in visual acuity (clarity of vision) with a high dose treatment with Aflibercept (Eylea) in patients suffering from neovascular age-related macular degeneration (nAMD). Neovascular AMD is an eye disease that causes blurred vision or a blind spot due to abnormal …

Tokyo Medical University Hachioji Medical Center
 (2.8 away) Contact site
  • 0 views
  • 11 Jun, 2021
  • +309 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

mini-mental state examination
florbetapir
alzheimer's disease
flortaucipir
positron emission tomography
P-one clinic
 (1.0 away) Contact site
  • 79 views
  • 13 Jun, 2021
  • +382 other locations
Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease

The primary objective of the study is to determine if treatment with high-dose aflibercept (HD) at intervals of 12 or 16 weeks provides non-inferior best corrected visual acuity (BCVA) compared to aflibercept dosed every 8 weeks. The secondary objectives of the study are as follows: To determine the effect of …

aflibercept
diabetic macular edema
diabetic retinopathy
swelling
corrected visual acuity
Regeneron Study Site
 (2.8 away) Contact site
  • 17 views
  • 14 May, 2021
  • +199 other locations
Etrasimod Versus Placebo as Induction Therapy in Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to assess the efficacy of etrasimod on clinical remission in participants with moderately to severely active ulcerative colitis (UC).

remission
endoscopy
Sagamihara Kyodo Hospital
 (5.0 away) Contact site
  • 12 views
  • 06 Jun, 2021
  • +414 other locations
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%

The purpose of this study is to evaluate the effect of finerenone compared to placebo (a tablet without active substance) in the reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart Failure (HF) events, including HF hospitalization and urgent visits …

nt-probnp
diuretic therapy
natriuretic peptide
stroke
b-type natriuretic peptide
Minamino Cardiovascular Hospital
 (3.1 away) Contact site
  • 0 views
  • 22 May, 2021
  • +761 other locations
Study of Adjuvant ONO-4538 With Resected Gastric Cancer

The purpose of study is to evaluate the efficacy and safety of postoperative adjuvant chemotherapy with Nivolumab in combination with tegafur-gimeracil-oteracil potassium (S-1 therapy) or capecitabine + oxaliplatin (CapeOX therapy), in comparison with placebo in combination with S-1 therapy or CapeOX therapy, in pStage III gastric cancer (including esophagogastric junction …

capecitabine
adenocarcinoma
gastric adenocarcinoma
carcinoma
tegafur
Kanagawa Clinical Site
 (7.3 away) Contact site
  • 174 views
  • 25 Jan, 2021
  • +106 other locations
Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

The primary objective of Part 1 of the study is to determine if BIIB093 improves functional outcome at Day 90 as measured by the modified Rankin Scale (mRS) when compared with placebo in participants with Large Hemispheric Infarction (LHI). The secondary objectives of Part 1 of the study are to …

thrombectomy
infarct
glibenclamide
glyburide
MRI
Research Site
 (8.3 away) Contact site
  • 213 views
  • 13 Jun, 2021
  • +221 other locations
A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

This study is designed to evaluate the long-term efficacy and safety of mirikizumab in participants with moderately to severely active ulcerative colitis (UC).

mirikizumab
Kitasato University Hospital
 (9.8 away) Contact site
  • 257 views
  • 13 Jun, 2021
  • +607 other locations
Assessing the Impact of Lipoprotein (a) Lowering With TQJ230 on Major Cardiovascular Events in Patients With CVD

This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)

Novartis Investigative Site
 (3.1 away) Contact site
  • 130 views
  • 05 Jun, 2021
  • +498 other locations