Fukuoka, Kurume, Japan Clinical Trials

A listing of Fukuoka, Kurume, Japan clinical trials actively recruiting patients volunteers.

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Found 68 clinical trials
A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy

The main aims of the study are: To check for side effects from TAK-994 and check what dose of TAK-994 participants can tolerate. To check what dose range provides adequate relief of narcolepsy symptoms. To check how much TAK-994 stays in the blood of participants, over time. The study will …

Kurume University Hospital
 (0.6 away) Contact site
  • 332 views
  • 04 Aug, 2021
  • +113 other locations
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizumab-based parent studies who roll-over into this extension study. This study will consist of three phases: 1) First Course Phase, 2) Survival Follow-up Phase or 3) Second Course Phase. …

metastasis
major surgery
pembrolizumab
mk-3475
Kurume University Hospital ( Site 3105)
 (0.6 away) Contact site
  • 522 views
  • 04 Aug, 2021
  • +267 other locations
Study to Gather Information About Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following a Recent Non Cardioembolic Ischemic Stroke Which Occurs When a Blood Clot Has Formed Somewhere in the Human Body (But Not in the Heart) Travelled to the Brain.

The purpose of this study is to try to find the best dose of the new drug BAY 2433334 to give to participants and to look at how well BAY 2433334 works on top of antiplatelet therapy in patients following a recent non cardioembolic ischemic stroke which occurs when a …

St.Mary's Hospital
 (1.0 away) Contact site
  • 45 views
  • 04 Aug, 2021
  • +261 other locations
Study of Amivantamab a Human Bispecific EGFR and cMet Antibody in Participants With Advanced Non-Small Cell Lung Cancer

The purpose of study is to evaluate the safety, pharmacokinetics, and preliminary efficacy of Amivantamab as a monotherapy and in combination with lazertinib, and to determine the recommended Phase 2 dose (RP2D) (monotherapy), recommended Phase 2 combination dose (RP2CD) (combination therapy), and to determine recommended Phase 2 Dose (RP2q3W) with …

growth factor
tyrosine
epidermal growth factor
kinase inhibitor
afatinib
Kurume University Hospital
 (0.6 away) Contact site
  • 0 views
  • 24 May, 2021
  • +105 other locations
A Study to Evaluate the Efficacy and Safety of Brivaracetam in Study Participants (>=16 to 80 Years of Age) With Epilepsy

The purpose of the study is to evaluate the efficacy of brivaracetam (BRV) compared to placebo (PBO) as adjunctive treatment in subjects (>=16 to 80 years of age) with partial seizures with or without secondary generalization despite current treatment with 1 or 2 concomitant antiepileptic drugs (AEDs) and to assess …

antiepileptics
seizure
brivaracetam
adjunctive treatment
partial seizure
Ep0083 126
 (0.0 away) Contact site
  • 840 views
  • 16 Jul, 2021
  • +110 other locations
Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma

This is a randomized, open-label, multi-center, global, Phase III study to assess the efficacy and safety of durvalumab plus tremelimumab combination therapy and durvalumab monotherapy versus sorafenib in the treatment of patients with no prior systemic therapy for unresectable HCC. The patients cannot be eligible for locoregional therapy.

durvalumab
cancer
sorafenib
systemic therapy
liver cancer
Research Site
 (0.0 away) Contact site
  • 272 views
  • 13 Jul, 2021
  • +247 other locations
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

This study, A3921210 is designed to evaluate the efficacy, safety and pharmacokinetics (PK) of tofacitinib in pediatric participants with moderately to severely active UC. In the US patients with prior TNFi failure or intolerance will be enrolled. Outside of the US, TNFi nave and TNFi experienced patients will be enrolled. …

mercaptopurine
remission
cancer
hematochezia
sulfasalazine
Kurume University Hospital
 (0.6 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +29 other locations
Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma (HCC) and Complete Radiological Response After Surgical Resection or Local Ablation (MK-3475-937 / KEYNOTE-937)

This study will evaluate the safety and efficacy of pembrolizumab (MK-3475) versus placebo as adjuvant therapy in participants with hepatocellular carcinoma (HCC) and complete radiological response after surgical resection or local ablation. The primary hypotheses of this study are that adjuvant pembrolizumab is superior to placebo with respect to: 1) …

ct scan
alpha fetoprotein
pembrolizumab
hepatitis
Kurume University Hospital ( Site 0119)
 (0.6 away) Contact site
  • 136 views
  • 04 Aug, 2021
  • +254 other locations
Study to Gather Information on Safety and Use of High Dose Aflibercept Injection Into the Eye in Patients With an Age Related Eye Disorder That Causes Blurred Vision or a Blind Spot Due to Abnormal Blood Vessels That Leak Fluid Into the Light Sensitive Lining Inside the Eye

In this study researchers want to learn more about changes in visual acuity (clarity of vision) with a high dose treatment with Aflibercept (Eylea) in patients suffering from neovascular age-related macular degeneration (nAMD). Neovascular AMD is an eye disease that causes blurred vision or a blind spot due to abnormal …

Kurume University Hospital
 (0.6 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +309 other locations
A Study to Test the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

The purpose of the study is to test the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS)

hidradenitis
abscess
bimekizumab
antibiotics
Hs0004 20170
 (0.0 away) Contact site
  • 342 views
  • 04 Aug, 2021
  • +100 other locations