San Giovanni Rotondo (FG), Italy Clinical Trials

A listing of San Giovanni Rotondo (FG), Italy clinical trials actively recruiting patients volunteers.

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Found 63 clinical trials
PN-943 in Adults With Moderate to Severe Active Ulcerative Colitis (UC)

The purpose of the study is to evaluate the safety, tolerability, and clinical efficacy of PN-943 450 mg twice daily [BID] and PN-943 150 mg BID, compared with placebo BID, in subjects with moderate to severe active Ulcerative Colitis (UC).

Protagonist Investigational Site
 (93.5 away) Contact site
  • 0 views
  • 20 Jul, 2021
  • +81 other locations
The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy

This is a randomized, prospective, multicenter, Proof of Concept, Phase II clinical trial Study. The main objective of the study is to evaluate the efficacy (meant as overall response rate ORR) of TT (targeted Therapy) vs SoC (standard of Care) in patients with progressive disease (recurrent and/or metastatic) of breast …

Irccs Oncologico Istituto Tumori Giovanni Paolo Ii - Bari
 (71.6 away) Contact site
  • 0 views
  • 16 May, 2021
  • +41 other locations
A Trial That Compare Two Treatments in Newly Diagnosed Myeloma Patients Not Eligible for Transplant

The combination of lenalidomide plus low-dose dexamethasone (Rd) is considered the new standard for elderly newly diagnosed multiple myeloma (NDMM) patients. The combination carfilzomib plus lenalidomide-dexamethasone (KRd) in relapsed-refractory MM patients improved the progression-free survival (PFS) of approximately 1 year compared to standard Rd treatment. In a small phase 2 …

Ospedale Oncologico Regionale
 (53.8 away) Contact site
  • 0 views
  • 28 Jan, 2021
  • +41 other locations
The Efficacy of Upper Limb Rehabilitation With Exoskeleton in Patients With Subacute Stroke.

Loss of arm function is a common and distressing consequence of stroke. Neurotechnology-aided rehabilitation could be a promising approach to accelerate the recovery of upper limb functional impairments. This multicentre randomized controlled trial is aimed at assessing the efficacy of robot-assisted upper limb rehabilitation in subjects with sub-acute stroke following …

Azienda Ospedaliero Universitaria Ospedali Riuniti
 (19.3 away) Contact site
  • 0 views
  • 27 Jan, 2021
  • +7 other locations
Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Colorectal Carcinoma. CHECK Study.

This is a phase III randomized, multicenter study with two different arm: experimental: prophylactic surgery plus HIPEC CO2 performed with mitomycin comparator: standard surgery Adjuvant treatment after surgery is mandatory except for documented cases of non-eligibility. Patient will be randomized in a 1:1 ratio. Randomization will be done during surgery …

IRCCS Istituto Tumori Giovanni Paolo II
 (71.6 away) Contact site
  • 0 views
  • 28 Jun, 2021
  • +15 other locations
Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Gastric Carcinoma.GOETH Study

This is a phase III randomized, multicenter study with two different arm: experimental: prophylactic surgery plus HIPEC CO2 performed with mitomycin and cisplatin comparator: standard surgery Adjuvant treatment after surgery is mandatory except for documented cases of non-eligibility in both arms. Patient will be randomized in a 1:1 ratio. Randomization …

immunostimulants
mitomycin
gastric carcinoma
carcinoma
cancer chemotherapy
IRCCS Istituto Tumori Giovanni Paolo II
 (71.6 away) Contact site
  • 0 views
  • 28 Jun, 2021
  • +11 other locations
A Multicenter Clinical Trial of Daratumumab in Combination With Gemcitabine Dexamethasone and Cisplatin in Patients With Relapsed/Refractory CD38 Positive PTCL-NOS Angioimmunoblastic T-cell Lymphoma AITL and Other Nodal Lymphomas of T Follicular Helper Cells Origin

FIL_Dara-GDP is a phase II, open label, multicenter clinical trial. The sponsor of this clinical trial is Fondazione Italiana Linfomi (FIL). The primary objective is to evaluate the efficacy of 4 courses of D-GDP (Daratumumab in combination with Gemcitabine, Cisplatin, Dexamethasone) in terms of complete response in patients with peripheral …

IRCCS Istituto Tumori Giovanni Paolo II - U.O.C Ematologia
 (71.6 away) Contact site
  • 0 views
  • 27 Mar, 2021
  • +19 other locations
Study of STI571 in the Treatment of Patients With Idiopathic Hypereosinophilic Syndrome (HES) and Eosinophilic Leukemias

The purpose of this study is to assess the clinical anti-proliferative activity of STI571 (Glivec®, Novartis, Pharma) in patients with HES defined as: 1. Idiopathic Hypereosinophilic Syndrome (secondary HES), defined as a peripheral blood eosinophilia greater than 1,500 cells/µL for longer than 6 months, absence of other apparent aetiologies for …

myelomonocytic leukemia
leukemia
chronic myelomonocytic leukemia
bone marrow procedure
bone marrow transplant
Dipartimento di Biochimica e Biotecnologie Mediche - Universit degli Studi di Napoli "Federico II"
 (98.1 away) Contact site
  • 10 views
  • 07 Nov, 2020
  • +13 other locations
Timing to Minimally Invasive Surgery After Neoadjuvant Chemoradiotherapy for Rectal Cancer

The trial is a multicenter, prospective, randomized controlled, unblinded, parallel-group trial comparing standard and delayed surgery after neoadjuvant chemoradiotherapy for the curative treatment of rectal cancer. Three-hundred and thirty-two patients will be randomized on an equal basis to either robotic-assisted/standard laparoscopic rectal cancer surgery after 8 weeks or robotic-assisted/standard laparoscopic …

chemoradiotherapy
low anterior resection
adenocarcinoma
cancer surgery
abdominoperineal resection
Ente Ecclesiastico ospedale generale Regionale Miulli
 (80.2 away) Contact site
  • 1 views
  • 01 Feb, 2021
  • +15 other locations
Sequential Chemotherapy and Blinatumomab to Improve MRD Response and Survival in Acute Lymphoblastic Leukemia

The present study aims at analyzing the response to treatment of adult patients homogeneously treated with supportive care, chemotherapy and blinatumomab.

lymphoid leukemia
corticosteroids
blinatumomab
cancer
UOC Ematologia Ospedale " Monsignor Raffaele Dimiccoli"
 (39.1 away) Contact site
  • 16 views
  • 24 Jan, 2021
  • +72 other locations