Kfar-Sava, Israel Clinical Trials

A listing of Kfar-Sava, Israel clinical trials actively recruiting patients volunteers.

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Found 43 clinical trials
Immunotherapy (Nivolumab and Ipilimumab) Before and After Surgery for the Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

This phase I trial studies the side effects of nivolumab and ipilimumab before and after surgery in treating children and young adults with high grade glioma that has come back (recurrent) or is increasing in scope or severity (progressive). Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help …

cytotoxic chemotherapy
cancer
neutrophil count
growth factor
tumor progression
Sheba Medical Center
 (9.0 away) Contact site
  • 0 views
  • 12 Sep, 2021
  • +11 other locations
Safety and Tolerability Study of Oral ABBV-744 Tablet Alone or in Combination With Oral Ruxolitinib Tablet or Oral Navitoclax Tablet in Adult Participants With Myelofibrosis

Myelofibrosis (MF) is a bone marrow illness that affects blood-forming tissues in the body. MF disturbs the body's normal production of blood cells, causing extensive scarring in the bone marrow. This leads to severe anemia, weakness, fatigue, and an enlarged spleen. The purpose of this study is to see how …

Sheba Medical Center /ID# 222151
 (9.0 away) Contact site
  • 15 views
  • 22 Aug, 2021
  • +44 other locations
Safety and Preliminary Efficacy of JBH492 Monotherapy in Patients With Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkin's Lymphoma (NHL)

The purpose of the First-In-Human study is to assess safety, tolerability, pharmacokinetics (PK), immunogenicity and preliminary efficacy of JBH492 as single agent.

leukemia
lymphoma
hodgkin's disease
lymphoid leukemia
chronic lymphocytic leukemia
Novartis Investigative Site
 (9.7 away) Contact site
  • 5 views
  • 04 Aug, 2021
  • +10 other locations
A Study of WVT078 in Patients With Multiple Myeloma (MM)

The design of a phase I, open-label, dose finding study was chosen in order to establish a safe and tolerated dose of single agent WVT078 alone and in combination with WHG626 in patients relapses and/or refractory Multiple Myeloma (MM)

refractory multiple myeloma
immunomodulatory imide drug
proteasome inhibitor
Novartis Investigative Site
 (9.7 away) Contact site
  • 8 views
  • 15 Sep, 2021
  • +12 other locations
An Efficacy and Safety Study of Cofetuzumab Pelidotin in Participants With PTK7-Expressing Recurrent Non-Small Cell Lung Cancer

This study is being done to determine the efficacy and safety of cofetuzumab pelidotin in the PTK7-expressing, recurrent non-small cell lung cancer (NSCLC) population.

lung cancer
recurrent non-small cell lung cancer
bone marrow procedure
systemic therapy
platinum-based chemotherapy
Rabin Medical Center /ID# 217537
 (6.6 away) Contact site
  • 6 views
  • 15 Sep, 2021
  • +28 other locations
A Study of the Combination of Talquetamab and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

The purpose of this study is to identify the recommended Phase 2 regimen(s) (RP2R[s]) and schedule for the study treatment (Part 1) and to characterize the safety of the RP2R(s) for the study treatment (Part 2). The RP2R(s) will describe the combination doses and schedules of (tal+tec+dara) the treatment combinations …

carfilzomib
human chorionic gonadotropin
refractory multiple myeloma
bortezomib
lenalidomide
Sheba Medical Center
 (9.0 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +13 other locations
Phase Ib Study of Select Drug Combinations in Patients With Lower Risk MDS

The purpose of this study is to characterize the safety, tolerability and confirm the dose for select single agents and combinations in patients with lower risk (very low, low, and intermediate risk) MDS.

myelodysplasia
anemia
lenalidomide
Novartis Investigative Site
 (9.7 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +6 other locations
Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. The purpose of this study is to evaluate the safety and efficacy …

docetaxel
platinum-based chemotherapy
epidermal growth factor
platinum doublet
targeted therapy
Sheba Medical Center /ID# 225585
 (9.0 away) Contact site
  • 0 views
  • 08 Aug, 2021
  • +29 other locations
A Study Investigate the Safety Tolerability Pharmacokinetic and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic Syndrome

This study will investigate the safety and tolerability of SLN124 in patients with Thalassaemia or patients with Very Low- and Low-risk Myelodysplastic Syndrome after single ascending s.c. doses and multiple doses in healthy male and female subjects. Up to 7 cohorts of 56 patients with Thalassaemia and up to 7 …

Israel
 (9.0 away) Contact site
  • 0 views
  • 22 Aug, 2021
  • +27 other locations
A Study of JNJ-70218902 in Participants With Advanced Stage Solid Tumors

The purpose of this study is to determine the recommended Phase 2 dose(s) (RP2D[s]) and maximum tolerated dose (MTD) of JNJ-70218902 in Part 1, and to determine the safety of JNJ-70218902 RP2D(s) in Part 2.

solid neoplasm
targeted therapy
primary cancer
adenocarcinoma
Sourasky Medical Center
 (9.7 away) Contact site
  • 17 views
  • 15 Sep, 2021
  • +10 other locations