Search Medical Condition
Please enter condition
Please choose location from dropdown
 

Waterford, Ireland Clinical Trials

A listing of Waterford, Ireland clinical trials actively recruiting patients volunteers.

RESULTS

Found (20) clinical trials

Plasma Biomarkers P-DAC V1

This study will involve two cohort groups, all patients involved will have PDAC. Cohort A: Target is 80 resectable PDAC patients who will receive standard treatment of chemotherapy +/- radiotherapy Cohort B: Cohort B1 = Target is 80 unresectable locally advanced PDAC patients who will receive standard treatment of chemotherapy ...

Phase N/A

0.0 miles

Learn More »

Plasma Biomarkers C-RAC ICORG 12-27 V1

Cohort A will consist of 100 CRAC patients with stage II/III resectable disease due for adjuvant chemotherapy. Cohort B will consist of 30 patients with stage II resectable disease for observation only. Both cohorts will have a follow up period of up to 2 years, post chemotherapy for cohort A ...

Phase N/A

0.0 miles

Learn More »

Anti-Mullerian Hormone Study. ICORG 10-16 V2

Type of Study: Translational Study Sample Type: A 10mL blood sample will be collected in red vacutainer tubes (no anticoagulant, no gel) from each patient at the designated time points +/- 7days. Blood should preferably be collected in the follicular phase of the menstrual cycle. Time of Sample procurement: 1st ...

Phase N/A

0.0 miles

Learn More »

Single Nucleotide Polymorphism(SNP)Study. ICORG 08-40 V4

Baseline assessment: Contact Lenses Medical History Previous chemotherapy Vital Signs (weight, height, Karnofsky Performance status, heart rate, blood pressure) Symptom Assessment (Pre-existing skin and/or eye conditions, CEA measurement (CRC only), Disease status (TNM Staging)) Planned chemotherapy regimen Radiotherapy Blood Sample: A 2ml blood sample should be collected in ethylenediamine-tetraacetic acid ...

Phase N/A

0.0 miles

Learn More »

A Translational Systems Medicine Approach to Provide Predictive Capacity for Therapy Response in Advanced or Metastatic Malignant Melanoma

This is an exploratory prospective translational multicentre study. Melanoma is the 5th most common cancer diagnosed in Ireland and its incidence among women and men is above the European average. Following treatment the elimination of cancer cells ultimately occurs by the activation of apoptotic cell death pathways. The SYS-ACT approach ...

Phase N/A

0.0 miles

Learn More »

TAILORx Tissue Bank

The primary objective is to develop a biobank, tissue microarrays (TMAs) and full face sections, which will be used to identify candidate/ novel biomarkers prognostic for disease relapse and predictive for endocrine and/or chemotherapy resistance. The secondary objectives are: To validate emerging signatures/biomarkers identified. To develop new assays for the ...

Phase N/A

0.0 miles

Learn More »

eSMART Trial to Evaluate ASyMS

Chemotherapy may cause distressing symptoms which can impact on patients' quality of life. Chemotherapy is frequently given on an outpatient basis therefore patients are often required to manage the symptoms they experience at home without direct supervision from healthcare professionals. This study aims to evaluate the impact of a mobile ...

Phase N/A

0.0 miles

Learn More »

Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer

Recent decades have witnessed a delay in childbearing for a variety of reasons including cultural, educational, and professional. As a consequence, breast cancer in young women often occurs before the completion of reproductive plans. Infertility has a significant impact on quality of life, resulting in substantial distress in younger women ...

Phase N/A

0.0 miles

Learn More »

Neoadjuvant Therapy in TRIPle Negative Breast Cancer With antiPDL1

Emerging evidence shows that many breast cancers with triple negative and basal like features have infiltration by mononuclear cells and lymphocytes. Irrespective of the entity of tumor infiltration by mononuclear cells, expression of immune regulatory checkpoints such as PD-1 and its ligand B7-H1 (or PD-L1) negatively affect the results of ...

Phase

0.0 miles

Learn More »

Comparison of Efficacy and Tolerability of Fulvestrant+Placebo vs Fulvestrant+Palbociclib as First Line Therapy for Postmenopausal Women With HR+ Metastatic BC Treated With 5 Years of Hormonal Therapy Remaining Disease Free More Than 12 Months After Completion or Have de Novo Metastatic Disease

This is an international, multicentre, double-blind, controlled, randomized phase II study comparing the efficacy and safety of fulvestrant in combination with palbociclib versus fulvestrant plus placebo in postmenopausal women with HR-positive/HER2-negative metastatic breast cancer who have received 5 years of endocrine therapy in the adjuvant setting as treatment for early ...

Phase

0.0 miles

Learn More »