Dublin 4, Ireland Clinical Trials

A listing of Dublin 4, Ireland clinical trials actively recruiting patients volunteers.

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Found 134 clinical trials
An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is a Phase 3, open-label, multicenter extension study to evaluate safety and efficacy of ozanimod in subjects with moderately to severely active Crohn's Disease.

crohn's disease
remission
Beaumont Hospital
 (4.1 away) Contact site
  • 1037 views
  • 22 Feb, 2021
  • +807 other locations
INTense ExeRcise for surviVAL Among Men With Metastatic Prostate Cancer (INTERVAL - GAP4)

To determine if supervised high intensity aerobic and resistance training increases overall survival compared to self-directed exercise in patients with metastatic prostate cancer.

enzalutamide
positron emission tomography
bone scan
adenocarcinoma
serum testosterone
Trinity University
 (1.9 away) Contact site
  • 1838 views
  • 25 Jan, 2021
  • +27 other locations
International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma

The study PNET 5 MB has been designed for children with medulloblastoma of standard risk (according to the risk-group definitions which have been used so far; e.g. in PNET 4). With the advent of biological parameters for stratification into clinical medulloblastoma trials, the -catenin status will be the only criterion …

medulloblastoma
nervous
metastasis
residual tumor
Our Lady's Children's Hospital
 (3.1 away) Contact site
  • 90 views
  • 21 Jan, 2021
  • +56 other locations
Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours

Add-Aspirin aims to assess whether regular aspirin use after standard curative therapy can prevent recurrence and improve survival in individuals with non-metastatic common tumours. The question will be assessed in four different tumour types (breast, colorectal, gastro-oesophageal and prostate) by means of parallel cohorts within an overarching trial protocol. Eligible …

aspirin
erbb2
adenocarcinoma of colon
liver metastasis
adjuvant chemotherapy
Beaumont Hospital
 (1.9 away) Contact site
  • 1429 views
  • 02 Mar, 2021
  • +83 other locations
A Phase I/II Study of Betalutin for Treatment of Relapsed Non-Hodgkin Lymphoma

This study is a phase I/II open-label study in patients with relapsed indolent NHL (Part A) or relapsed/refractory FL (Part B). Part A of the study assessed the safety and preliminary efficacy. This seamless design study now has four parts: 1) Part A, Ph I - dose escalation, 2) Part …

rituximab
alkylating agent
platelet count
follicular lymphoma
refractory follicular lymphoma
 (1.9 away) Contact site
  • 402 views
  • 11 Apr, 2021
  • +156 other locations
Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations

This is an open-label, multicenter, multinational, Phase 2 basket study exploring the efficacy and safety of neratinib as monotherapy or in combination with other therapies in participants with HER (EGFR, HER2) mutation-positive solid tumors.

St. Vincent's University Hospital
 (1.1 away) Contact site
  • 83 views
  • 26 Sep, 2021
  • +72 other locations
Abatacept for the Treatment of Relapsing Non-Severe Granulomatosis With Polyangiitis (Wegener's)

Multi-center, randomized, double-blind, placebo-controlled trial to evaluate the efficacy of abatacept to achieve sustained glucocorticoid-free remission in patients with relapsing non-severe granulomatosis with polyangiitis (Wegener's) (GPA) . Participants will be randomized 1:1 to receive either abatacept 125 mg or placebo administered by subcutaneous injection once a week. Participants will continue …

cavities
remission
urinary sediment
eosinophilic granulomatosis
anca
St. Vincent's University Hospital
 (1.9 away) Contact site
  • 197 views
  • 28 Apr, 2021
  • +25 other locations
Study of the Efficacy and Safety of Immune Globulin Intravenous (Human) Flebogamma 5% DIF in Patients With Post-polio Syndrome

This is a multicenter, prospective, randomized, placebo-controlled, double-blind, parallel group clinical trial with adaptive dose selection in subjects with post-polio syndrome (PPS). The main purpose of this study is to select a dose of Flebogamma 5% DIF and confirm the efficacy of the selected Flebogamma 5% DIF dose by assessing …

Beaumont Hospital
 (3.5 away) Contact site
  • 167 views
  • 09 Sep, 2021
  • +55 other locations
Phase III Radium 223 mCRPC-PEACE III

The objective of this randomized phase III open label trial is to assess if upfront combination of enzalutamide and Ra223 improves radiological progression-free survival compared to enzalutamide single agent in asymptomatic or mildly symptomatic castration resistant prostate cancer patients metastatic to bone.

neutrophil count
dexamethasone
enzalutamide
diphosphonates
bone scan
St. Vincent's University Hospital
 (1.9 away) Contact site
  • 504 views
  • 25 Jan, 2021
  • +57 other locations
Study of SRP-4045 and SRP-4053 in Participants With Duchenne Muscular Dystrophy (DMD)

The main objective of this study is to evaluate the efficacy of SRP-4045 and SRP-4053 compared to placebo in participants with DMD with out-of-frame deletion mutations amenable to skipping exon 45 and exon 53, respectively.

corticosteroids
muscular dystrophy
duchenne muscular dystrophy
deletion mutation
forced vital capacity
The Children's University Hospital
 (2.3 away) Contact site
  • 0 views
  • 25 Aug, 2021
  • +80 other locations