Dublin 4, Ireland Clinical Trials

A listing of Dublin 4, Ireland clinical trials actively recruiting patients volunteers.

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Found 138 clinical trials
Methoxyflurane Analgesia for Paediatric Injuries

This is a randomised, double-blind, multicentre, placebo controlled study to evaluate the safety and efficacy of methoxyflurane (Penthrox) for the treatment of acute pain in children and adolescents from 6 to less than 18 years of age (presenting to an Emergency Department with minor trauma). It is conducted as part …

methoxyflurane
penthrox
analgesia
pain in children
Our Lady's Children's Hospital
 (3.7 away) Contact site
  • 5 views
  • 06 Mar, 2021
  • +9 other locations
A Randomised Controlled Trial of Family Mediated Exercises (FAME) Following Stroke

The aim of the study is to evaluate the functional recovery in two groups of primary stroke patients presenting with moderate/severe disability over a six month period through the implementation of a randomised controlled trial. The first group or the experimental group will receive routine therapy and additional lower limb …

Beaumont Hospital
 (1.9 away) Contact site
  • 112 views
  • 07 Nov, 2020
  • +1 other locations
Epirubicin Oxaliplatin and Capecitabine or Docetaxel and Oxaliplatin in Treating Patients With Advanced Esophageal Cancer Gastroesophageal Junction Cancer or Stomach Cancer

RATIONALE: Drugs used in chemotherapy, such as epirubicin, oxaliplatin, capecitabine, and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet …

docetaxel
combination chemotherapy
capecitabine
tumor cells
epirubicin
Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital
 (1.8 away) Contact site
  • 134 views
  • 07 Nov, 2020
  • +2 other locations
Efficacy of Multimodal Opioid Therapy During Hepatic Resection Surgery

The patient population requiring hepatic resection can demonstrate an unpredictable risk of exhibiting peri-operative coagulopathy resulting either from the pre-operative hepatic pathophysiology or volume of parenchymal resection. Choice of analgesia can be severely limited. Currently, the most commonly described use of combined remifentanil infusion and intrathecal morphine has been in …

morphine
opioid
remifentanil
pain relieving
analgesia
St. Vincent's University Hospital
 (2.2 away) Contact site
  • 30 views
  • 07 Nov, 2020
  • 1 location
The Safety and Efficacy Of Psilocybin as an Adjunctive Therapy in Participants With Treatment Resistant Depression

A recent open label study of the effects of psilocybin in participants with treatment-resistant depression (TRD) showed rapid significant decrease of depressive symptoms after treatment with psilocybin coupled with psychological support. Over 40% of participants sustained response at 3 months. In this study, the aim is to explore effectiveness of …

Sheaf House, Tallaght Hospital
 (1.9 away) Contact site
  • 0 views
  • 28 Jul, 2021
  • +1 other locations
Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic Acid

Osteogenesis imperfecta (OI) is an inherited skeletal disorder characterised by increased risk of fragility fractures. Bisphosphonates are frequently prescribed for adult patients with OI with the aim of preventing fractures but the evidence base for efficacy is poor. Recent evidence suggests that the bone anabolic agent teriparatide (TPTD) increases bone …

teriparatide
bone mineral density
zoledronic acid
bisphosphonate
parathyroid hormone
St Vincent's Hospital
 (0.9 away) Contact site
  • 120 views
  • 22 Jan, 2021
  • +23 other locations
A Study to Evaluate the Pharmacokinetics Safety and Tolerability of Upadacitinib in Pediatric Participants With Severe Atopic Dermatitis

The objective of this study is to evaluate the safety, pharmacokinetics and tolerability of multiple doses of upadacitinib in pediatric participants with severe atopic dermatitis and to evaluate palatability of upadacitinib oral solution in pediatric participants (Cohorts 1 to 4 only).

calcineurin inhibitor
eczema
topical corticosteroid
atopy
topical agents
Our Lady's Children's Hospital /ID# 211199
 (3.7 away) Contact site
  • 239 views
  • 10 May, 2021
  • +18 other locations
Innovative Food Structures to Enhance Nutrient Bioavailability

This randomized controlled trial (RCT) will compare the change in vitamin D status (25-hydroxyvitamin D nmol/L) after a 4 week intervention with 4 groups: Vitamin D enriched (20ug) olive oil emulsion drink Vitamin D enriched (20ug) coconut oil emulsion drink Placebo emulsion drink Vitamin D supplement (20ug) Participants will be …

25-hydroxyvitamin d3
calcifediol
vitamins
calcidiol
vitamin d supplements
University College Dublin
 (1.9 away) Contact site
  • 283 views
  • 23 Jan, 2021
  • 1 location