Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters

Dublin 24, Ireland Clinical Trials

A listing of Dublin 24, Ireland clinical trials actively recruiting patients volunteers.

RESULTS

Found (61) clinical trials

Percutaneous Nephrostomy Versus Stent In Sepsis Trial

The obstructed kidney in the setting of urosepsis is a urological emergency. Stone manipulation in the setting of active, untreated infection with concomitant urinary tract obstruction can lead to life-threatening sepsis. Therefore, urgent decompression of the collecting system is warranted. There are two options for urgent decompression of an obstructed ...

Phase N/A

0.7 miles

Learn More »

A Long-Term Registry of Humira (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)

This is a registry study to evaluate the long-term safety and effectiveness of adalimumab in patients with moderately to severely active UC who are treated as recommended in the product label.

Phase N/A

0.73 miles

Learn More »

Evaluating the Side Effects and How Well Anticancer Drugs Work in Very Young Patients With Cancer

OBJECTIVES: - Investigate inter-individual variability in the pharmacokinetics of selected anticancer drugs in infants and children age < 2 years on current dosing schedules. - Compare drug exposures and degree of pharmacokinetic variability in children < 2 years with data obtained from published studies in older children. - Relate inter-individual ...

Phase N/A

4.6 miles

Learn More »

Pharmacokinetics of Dactinomycin in Young Patients With Cancer

OBJECTIVES: - Determine the pharmacokinetics (PKs) of dactinomycin in pediatric patients with cancer. - Determine the degree of interpatient variation in the PKs of this drug. - Determine the influence of characteristics such as age, tumor type, and concurrent therapy on drug PKs in these patients. - Correlate drug PKs ...

Phase N/A

4.6 miles

Learn More »

Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01

OBJECTIVES: - Determine the late effects of treatment and the quality-of-life of patients with germ cell tumors (GCT) previously treated on clinical trial CCLG-GC-1979-01 or CCLG-GC-1989-01. - Evaluate the late effects of carboplatin, etoposide, and bleomycin in patients treated on clinical trial CCLG-GC-1989-01. - Determine the toxicity of bleomycin and ...

Phase N/A

4.6 miles

Learn More »

CYP3A5 Gene as a Risk Factor for Kidney Damage in Young Patients With Cancer Treated With Ifosfamide

OBJECTIVES: Primary - To determine the CYP3A5 genotype in young patients with cancer who have received ifosfamide. - To document renal function and nephrotoxicity on one occasion between 1 month and 5 years after completion of ifosfamide treatment. - To determine the relationship between CYP3A5 genotype and ifosfamide nephrotoxicity. Secondary ...

Phase N/A

4.6 miles

Learn More »

Sleep Disturbance in Patients With End-Stage Renal Disease

Patients will not selected based on presence/absence of sleep disturbance. Patients will be prioritized for recruitment if they were active on the transplant waitlist or a change in RRT modality is planned. Patients will be selected for inclusion if they were >16 years old, competent to independently undertake the informed ...

Phase N/A

4.67 miles

Learn More »

Proof -of -Concept Study To Stratify Targeted Therapies Adapted To Molecular Profiling

In the light of the development of high-throughput technologies enabling a biology-based reclassification of tumors and the increasing number of available specifically targeting anticancer agents the era of "precision medicine" has begun. Several clinical precision medicine trials with the aim of stratifying treatment according to molecular profiles (for example in ...

Phase N/A

4.87 miles

Learn More »

Optimum Duration of Compression Stockings After Endovenous Varicose Vein Surgery

The Nice Guidelines for Varicose Veins, published by the NHS in 2013, questioned the clinical benefit of stockings after endovenous ablation, and if there is benefit, how long the stockings should be worn for. Three randomised controlled trials have addressed these issues: Bakker and colleagues randomised 69 patients into two ...

Phase N/A

5.0 miles

Learn More »

Inhaler Adherence in Severe Unstable Asthma

The investigators hypothesize that aligning adherence, inhaler technique and digitally recorded PEF to inform patients and as the basis of prescribing decisions achieves better inhaler adherence and technique and also allows physicians to make appropriate prescribing decisions, compared to current best practice. The investigators will compare two asthma education interventions, ...

Phase N/A

5.09 miles

Learn More »