Miskolc, Hungary Clinical Trials

A listing of Miskolc, Hungary clinical trials actively recruiting patients volunteers.

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Found 72 clinical trials
Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

The study will evaluate the efficacy and safety of trastuzumab deruxtecan (also known as T-DXd, DS-8201a), either alone or in combination with pertuzumab, in treating patients with Human epidermal growth factor receptor 2 (HER2)-positive breast cancer as a first line of treatment.

Research Site
 (1.4 away) Contact site
  • 2 views
  • 11 Sep, 2021
  • +224 other locations
A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the efficacy of ustekinumab dosing in inducing clinical remission (Global) and in maintaining clinical remission (US); to evaluate the safety profile and ustekinumab exposure (pharmacokinetics [PK]) in pediatric participants with moderately to severely active Crohn's disease.

ileitis
colitis
crohn's disease
remission
endoscopy
Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz
 (1.4 away) Contact site
  • 0 views
  • 08 Sep, 2021
  • +56 other locations
Zibotentan and Dapagliflozin for the Treatment of CKD (ZENITH-CKD Trial)

The purpose of the study is to assess efficacy, safety and tolerability of treatment with zibotentan and dapagliflozin in combination and alone, compared with placebo in participants with chronic kidney disease (CKD) with estimated glomerular filtration rate (eGFR) between 20 and 60 mL/min/1.73^2.

Research Site
 (1.4 away) Contact site
  • 19 views
  • 15 Sep, 2021
  • +151 other locations
Pembrolizumab Plus Lenvatinib for First-line Advanced/Metastatic Non-clear Cell Renal Cell Carcinoma (1L nccRCC) (MK-3475-B61)

This study is being performed as a single-arm open-label study in order to rapidly provide information on the potential benefits of the combination of pembrolizumab and lenvatinib in participants with previously untreated advanced/metastatic non-clear cell renal cell carcinoma.

measurable disease
clear cell renal cell carcinoma
carcinoma
pembrolizumab
progressive disease
Borsod-Aba j-Zempl n Megyei K zponti K rh z s Egyetemi Okta-Klinikai Onkol giai s Sug rter pi s C
 (1.4 away) Contact site
  • 0 views
  • 08 Sep, 2021
  • +55 other locations
A Study to Test the Safety and Tolerability of Brivaracetam in Pediatric Study Participants With Seizures

The purpose of the study is to evaluate the long-term safety and tolerability of brivaracetam.

electroencephalogram
brivaracetam
antiepileptics
seizure
Ep0156 247
 (90.5 away) Contact site
  • 0 views
  • 01 Sep, 2021
  • +23 other locations
A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (UC)

The purpose of this study is to evaluate: a) the efficacy of ustekinumab dosing in inducing clinical remission, b) safety profile of ustekinumab, and c) ustekinumab exposure (pharmacokinetics [PK]) in pediatric participants with moderately to severely active UC.

remission
endoscopy
Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz
 (1.4 away) Contact site
  • 0 views
  • 11 Sep, 2021
  • +57 other locations
Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure Obesity and Type 2 Diabetes

This study will look at how participants' daily life is affected by their heart failure. The study will also look at the change in participants' body weight. This study will compare the effect of semaglutide (a new medicine) compared to "dummy" medicine on body weight and heart failure symptoms. Participants …

Novo Nordisk Investigational Site
 (4.7 away) Contact site
  • 7 views
  • 22 Sep, 2021
  • +59 other locations
A Study of Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005)

The primary objective of this study is to compare belzutifan to everolimus with respect to progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as assessed by Blinded Independent Central Review (BICR) and to compare everolimus with respect to overall survival (OS). The hypothesis is …

clear cell renal cell carcinoma
everolimus
tyrosine
carcinoma
kinase inhibitor
Borsod-Abauj-Zemplen Megyei Kozponti Korhaz es Egyetemi Oktatokorhaz ( Site 0502)
 (1.4 away) Contact site
  • 168 views
  • 24 Sep, 2021
  • +182 other locations
Study on a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Compared to a Meningococcal Reference Vaccine and When Given Alone or With Two Other Vaccines in Healthy Adolescents

Primary Objective: To demonstrate the non-inferiority of the seroprotection rate (serum bactericidal assay using human complement [hSBA] titer 1:8) to meningococcal serogroups A, C, W, and Y following the administration of a single dose of MenACYW conjugate vaccine (Group 1) compared to a single dose of Nimenrix (Group 2) Secondary …

Investigational Site Number :3480002
 (1.9 away) Contact site
  • 0 views
  • 22 Aug, 2021
  • +29 other locations
Functional Respiratory Imaging Study

The purpose of this study is to evaluate the stepping-up effect from a double ICS/LABA DPI therapy to a triple DPI therapy on airway geometry and lung ventilation

CRU Hungary Ltd
 (0.8 away) Contact site
  • 0 views
  • 02 Aug, 2021
  • +7 other locations