Sha Tin, Hong Kong Clinical Trials

A listing of Sha Tin, Hong Kong clinical trials actively recruiting patients volunteers.

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Found 23 clinical trials
A Study to Evaluate the Reactogenicity Safety Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' HBV (Hepatitis B Virus) Viral Vector Vaccines and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection.

A First-Time-In-Human study on GSK's therapeutic vaccines to evaluate the reactogenicity, safety, immunogenicity and efficacy on reduction of serum HBV surface antigen in HBV suppressed subjects under nucleo(s)tide treatment.

hepatitis b e antigen
hepatitis b surface
vaccination
cirrhosis
hepatitis b core antibody
GSK Investigational Site
 (8.7 away) Contact site
  • 16 views
  • 05 Jun, 2021
  • +33 other locations
Safety Efficacy and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors

This study will be conducted to assess the safety and tolerability of BOS172738 when administered to patients with advanced solid tumors with rearranged during transfection (RET) gene alterations and also to establish the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) of BOS172738.

Prince of Wales Hospital
 (4.4 away) Contact site
  • 33 views
  • 05 Mar, 2021
  • +28 other locations
Rollover Study for Continued Safety and Tolerability in Subjects Treated With Spartalizumab Alone or in Combination With Other Study Treatments

The purpose of this study is to continue to assess safety and tolerability, and to allow continued access to study treatment for subjects already receiving spartalizumab as single agent or in combination with other study treatments.

Novartis Investigative Site
 (4.4 away) Contact site
  • 0 views
  • 12 Jun, 2021
  • +33 other locations
Study of Safety and Tolerability of DCR HBVS

DCR-HBVS will be evaluated for safety and efficacy in healthy volunteers and chronic hepatitis B patients.

liver disease
chronic hepatitis
Queen Mary Hospital (The University of Hong Kong)
 (4.4 away) Contact site
  • 150 views
  • 25 Jan, 2021
  • +8 other locations
A Study to Evaluate Safety and Immunogenicity of DelNS1-nCoV-RBD LAIV for COVID-19

To investigate the safety and immunogenicity profile of of a novel nasal spray investigational vaccine, which is a potential prophylactic vaccine for current pandemic disease COVID-19.

HKU Phase 1 Clinical Trials Centre
 (4.4 away) Contact site
  • 0 views
  • 10 May, 2021
  • 1 location
A Study of EDP-514 in Patients With Chronic Hepatitis B Virus Infection Who Are Not Currently on Treatment

This is a randomized, double-blind, placebo-controlled study in viremic chronic hepatitis B subjects, assessing the safety, tolerability, pharmacokinetics and antiviral activity of 28 Days treatment with EDP-514.

Queen Mary Hospital
 (4.4 away) Contact site
  • 0 views
  • 16 May, 2021
  • +9 other locations
Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).

This is a Phase Ib, open label, dose escalation study of spartalizumab + LAG525 in combination with NIR178, capmatinib, MCS110, or canakinumab, followed by a dose expansion in adult patients with advanced or metastatic TNBC. During the dose-escalation part of each treatment arm, patients will be treated with fixed doses …

taxane
progesterone receptor
erbb2
estrogen
progesterone
Novartis Investigative Site
 (1609.2 away) Contact site
  • 44 views
  • 15 Jun, 2021
  • +12 other locations
Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal Gastroesophageal and Renal Cancers

This study will determine the pharmacodynamically-active dose of gevokizumab and the tolerable dose and preliminary efficacy of gevokizumab in combination with the standard of care anti-cancer therapy in patients with metastatic colorectal cancer, metastatic gastroesophageal cancer and metastatic renal cell carcinoma.

metastatic renal cell carcinoma
curative surgery
paclitaxel
metastatic cancer
oxaliplatin
Novartis Investigative Site
 (8.7 away) Contact site
  • 74 views
  • 02 Jun, 2021
  • +46 other locations
Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLC

The study purpose is to evaluate the safety, tolerability, and preliminary efficacy of the addition of INC280, trametinib, ribociclib, gefitinib, or LXH254 to EGF816 in adult patients with advanced EGFR-mutant NSCLC.

Novartis Investigative Site
 (385.3 away) Contact site
  • 7 views
  • 14 May, 2021
  • +9 other locations
A Study to Test Different Doses of BI 836880 Combined With BI 754091 in Patients With Advanced Non-small Cell Lung Cancer Followed by Other Types of Advanced Solid Tumours

This study has 2 parts. The first part is open to adults with advanced non-small cell lung cancer. The second part is open also to adults with other types of advanced cancer of the lung, brain, skin, and liver. The participants get a combination of two medicines called BI 836880 …

glioblastoma multiforme
alopecia
neuropathy
primary cancer
solid neoplasm
Queen Mary Hospital
 (4.4 away) Contact site
  • 17 views
  • 15 May, 2021
  • +62 other locations