Radeberg, Germany Clinical Trials

A listing of Radeberg, Germany clinical trials actively recruiting patients volunteers.

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Found 72 clinical trials
Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or S zary Syndrome (SS)

The purpose of this study is to determine whether resminostat will be able to delay or prevent worsening of disease in patients with advanced stage mycosis fungoides or Szary Syndrome that have recently achieved disease control with previous systemic therapy.

chemotherapy regimen
maintenance treatment
renal function test
Universitaetsklinikum Dresden
 (8.8 away) Contact site
  • 17 Sep, 2021
  • +91 other locations
A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)

This study will assess the antitumor activity, safety, tolerability, and pharmacokinetics (PK) of the Mesenchymal-epithelial Transition Factor (MET) inhibitor tepotinib combined with the 3rd generation EGFR inhibitor osimertinib in participants with advanced or metastatic non-small cell lung cancer (NSCLC).

growth factor
stage iv non-small cell lung cancer
lung carcinoma
epidermal growth factor
Universitaetsklinikum Carl Gustav Carus TU Dresden
 (7.4 away) Contact site
  • 12 Sep, 2021
  • +182 other locations
Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sj gren's Syndrome

This study will evaluate safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of multiple doses of CFZ533 (iscalimab) in patients with Sjgren's Syndrome.

Novartis Investigative Site
 (7.4 away) Contact site
  • 22 Aug, 2021
  • +74 other locations
A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

The purpose of this study is evaluate the efficacy of teclistamab at the recommended Phase 2 dose (RP2D).

measurable disease
multiple myeloma
Universit tsklinikum Carl-Gustav-Carus Dresden
 (7.4 away) Contact site
  • 19 Sep, 2021
  • +71 other locations
Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma

The primary purpose of this study is to evaluate the efficacy of LXH254 combinations in previously treated unresectable or metastatic melanoma

metastatic melanoma
targeted therapy
metastatic cutaneous melanoma
Novartis Investigative Site
 (7.4 away) Contact site
  • 27 Jul, 2021
  • +34 other locations
A Study to Evaluate the Effects of GLPG2737 in Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

This exploratory, randomized, double-blind, placebo-controlled, multicenter, proof of concept, Phase 2a study will evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of orally administered GLPG2737, for a treatment period of 52 weeks, in participants with rapidly progressing ADPKD.

Uniklinikum Dresden
 (7.4 away) Contact site
  • 11 Jul, 2021
  • +17 other locations
HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer

This study is designed to evaluate the antitumor activity of patritumab deruxtecan in participants with metastatic or locally advanced NSCLC with an activating EGFR mutation (exon 19 deletion or L858R) who have received and progressed on or after at least 1 EGFR TKI and 1 platinum-based chemotherapy-containing regimen.

University Cancer Center
 (7.4 away) Contact site
  • 21 Aug, 2021
  • +89 other locations
Efficacy Safety and Tolerability of AZD9977 and Dapagliflozin in Participants With Heart Failure and Chronic Kidney Disease

The purpose of the study is to evaluate the efficacy and safety of AZD9977 alone and AZD9977 in combination with dapagliflozin and to assess the dose-response relationship of placebo, AZD9977 alone, dapagliflozin alone and 3 doses of AZD9977 combined with dapagliflozin on urinary albumin to creatinine ratio (UACR). The study …

ejection fraction
natriuretic peptide
antihypertensive drugs
body mass index
Research site
 (9.3 away) Contact site
  • 29 Aug, 2021
  • +141 other locations
A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag

Oral selexipag is commercially available in several countries for the treatment of a particular group of pulmonary hypertension (PH) called pulmonary arterial hypertension (PAH). The aim of the present study is to investigate whether selexipag could be helpful to treat patients with another form of PH called sarcoidosis-associated pulmonary hypertension …

Universitatsklinikum Carl Gustav Carcus Dresden
 (7.4 away) Contact site
  • 12 Sep, 2021
  • +76 other locations
Study of TL-895 in Subjects With Myelofibrosis

This study evaluates TL-895, a potent, orally-available and highly selective irreversible tyrosine kinase inhibitor for the treatment of Myelofibrosis. Participants must be relapsed/refractory (e.g., having failed prior therapy), intolerant, or ineligible to receive JAKi treatment.

Universitaetsklinikum Carl Gustav Carus Dresden
 (8.8 away) Contact site
  • 22 Sep, 2021
  • +33 other locations