Radeberg, Germany Clinical Trials

A listing of Radeberg, Germany clinical trials actively recruiting patients volunteers.

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Found 72 clinical trials
Daratumumab Retreatment in Participants With Multiple Myeloma Who Have Been Previously Treated With Daratumumab

The purpose of this study is to compare the efficacy (rate of very good partial response [VGPR] or better as best response as defined by the International Myeloma Working Group [IMWG] criteria) of daratumumab subcutaneous (Dara-SC) in combination with carfilzomib and dexamethasone (Kd) with the efficacy of Kd in participants …

refractory multiple myeloma
progressive disease
Universit tsklinik Carl Gustav Carus, Med. Klinik u. Poliklinik I
 (7.4 away) Contact site
  • 15 Sep, 2021
  • +163 other locations
Trial to Determine the Efficacy and Safety of JCAR017 in Adult Subjects With Aggressive B-Cell Non-Hodgkin Lymphoma

This open-label Phase 2 study will evaluate the safety and efficacy of modified T cells (JCAR017) administered to adult patients with aggressive B-cell non-Hodgkin lymphoma (NHL). The study will also help determine how long the modified T cells stay in the patient's body. Furthermore, changes in the patient's quality of …

gilbert's syndrome
hodgkin's disease
follicular lymphoma
b-cell lymphoma
Medizinische Kinik und Poliklinik I
 (7.4 away) Contact site
  • 25 Jun, 2021
  • +28 other locations
A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy

The purpose of the study is to evaluate the efficacy of perampanel as measured by the 50 percent (%) responder rate during the maintenance period of the core study for seizure frequency in participants with pediatric epileptic syndrome (Cohort 1) and partial-onset seizures (POS) (Cohort 2).

Fakultni nemocnice Plzen
 (97.5 away) Contact site
  • 12 Sep, 2021
  • +57 other locations
IMMUNOtherapy and Stereotactic ABlative Radiotherapy (IMMUNOSABR) a Phase II Study

This will be a phase II trial testing if the combination of stereotactic ablative body radiotherapy (SABR) and L19-IL2 improve the progression-free survival in patients with limited metastatic non-small cell lung cancer (NSCLC). The trial consists of one cohort with two arms; C-arm and an E-arm. Patients with oligometastatic disease …

neutrophil count
measurable disease
liver metastasis
stereotactic body radiation therapy
University Hospital Carl Gustav Carus
 (8.8 away) Contact site
  • 26 Jan, 2021
  • +19 other locations
Efficacy and Safety of LNP023 Compared With Rituximab in Subjects With Idiopathic Membranous Nephropathy

This is a randomized, open-label, two arm, parallel group, proof-of-concept, non-confirmatory study evaluating the efficacy and safety of LNP023 compared with rituximab in subjects with membranous nephropathy (MN) who are at high risk of disease progression defined on the basis of antibody anti-PLA2R titre and proteinuria.

kidney biopsy
Novartis Investigative Site
 (7.4 away) Contact site
  • 14 Jul, 2021
  • +30 other locations
Investigating the Combination of VB10.16 and Atezolizumab in Patients With HPV 16-positive Cervical Cancer

This phase IIa study is designed to evaluate the safety and efficacy of multiple dosing with VB10.16 immunotherapy in combination with atezolizumab in patients with advanced or recurrent non-resectable HPV16-positive cervical cancer, who failed or are not eligible for current standard of care.

measurable disease
human papilloma virus vaccine
University Clinic Carl Gustav Carus
 (8.8 away) Contact site
  • 13 May, 2021
  • +20 other locations
Domatinostat in Combination With Avelumab in Patients With Advanced Merkel Cell Carcinoma Progressing on Anti-PD-(L)1

This phase II trial studies how well domatinostat (4SC-202) works in combination with avelumab in adult patients with advanced unresectable and/or metastatic Merkel Cell Carcinoma that have progressed on a previous therapy with an anti-PD-(L)1 antibody

metastatic merkel cell carcinoma
Universit tsklinikum Dresden
 (8.8 away) Contact site
  • 05 Jul, 2021
  • +44 other locations
A Study of AZD4635 With Durvalumab and With Cabazitaxel and Durvalumab in Patients With mCRPC.

This is a Phase II, international, open-label, two-arm, non-randomised study of AZD4635 in participants with metastatic castration-resistant prostate cancer (mCRPC).

Research Site
 (7.4 away) Contact site
  • 20 Sep, 2021
  • +42 other locations
A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema

This study is conducted to select the THR-149 dose level (Part A of the study) and to assess the efficacy and safety of the selected dose level compared to aflibercept (Part B of the study).

macular edema
diabetic macular edema
optical coherence tomography
vascular endothelial growth factor
Universit tsklinikum Carl Gustav Carus Dresden
 (7.4 away) Contact site
  • 18 Sep, 2021
  • +38 other locations
TRIgyceride And Glucose Control With Epeleuton in Metabolic Syndrome Patients

To assess the efficacy and safety of orally administered Epeleuton capsules versus placebo, in the treatment of adult patients with hypertriglyceridemia and type 2 diabetes

type 2 diabetes mellitus
metabolic syndrome
hemoglobin a1c
Germany Site 7
 (8.8 away) Contact site
  • 17 Sep, 2021
  • +26 other locations