Hennigsdorf, Germany Clinical Trials

A listing of Hennigsdorf, Germany clinical trials actively recruiting patients volunteers.

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Found 251 clinical trials
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Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis (MF) is a bone marrow illness that affects blood-forming tissues in the body. MF disturbs the body's normal production of blood cells, causing extensive scarring in the bone marrow. This leads to severe anemia, weakness, fatigue, and an enlarged spleen. The purpose of this study is to assess …

Charite Campus Virchow-Klinikum /ID# 223949
 (8.8 away) Contact site
  • 164 views
  • 29 Apr, 2021
  • +224 other locations
Efficacy and Safety of Pembrolizumab (MK-3475) With Lenvatinib (E7080/MK-7902) vs. Docetaxel in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) and Progressive Disease (PD) After Platinum Doublet Chemotherapy and Immunotherapy (MK-7902-008/E7080-G000-316/LEAP-008)

This study will evaluate the efficacy and safety of pembrolizumab (MK-3475) with lenvatinib (E7080/MK-7902) vs. docetaxel in participants with metastatic non-small cell lung cancer (NSCLC) and progressive disease (PD) after platinum doublet chemotherapy and treatment with one prior anti-PD-1/PD-L1 monoclonal antibody (mAb). The primary hypotheses of this study are that …

metastasis
measurable disease
progressive disease
mk-3475
pembrolizumab
Vivantes Klinikum Spandau ( Site 0505)
 (5.9 away) Contact site
  • 122 views
  • 12 Jun, 2021
  • +147 other locations
Multiple Dose Safety and Efficacy of LKA651 in Patients With Diabetic Macular Edema

To evaluate the safety and efficacy of LKA651 in patients with macular edema from diabetic macular edema (DME),

type 2 diabetes mellitus
spectral domain optical coherence tomography
lucentis
diabetes
Novartis Investigative Site
 (8.8 away) Contact site
  • 126 views
  • 24 May, 2021
  • +22 other locations
Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure

The objective of the study is to demonstrate that in patients with chronic heart failure who receive optimal medical treatment for this condition and have indication for Cardiac Resynchronisation Therapy, the implantation of a pacemaker (index group) is not inferior to defibrillator (control group) with respect to all-cause mortality.

cardiac resynchronization therapy
ejection fraction
cardiomyopathy
medical therapy
Vivantes Klinikum Spandau
 (5.9 away) Contact site
  • 2 views
  • 16 Jun, 2021
  • +349 other locations
Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

A Phase 3, 22-week, Multi-center, Randomized Withdrawal Study of ampreloxetine in Treating Symptomatic Neurogenic Orthostatic Hypotension in Subjects with Primary Autonomic Failure

Charite - Campus Virchow-Klinikum, Klinik fur Neurologie
 (8.8 away) Contact site
  • 11 views
  • 23 May, 2021
  • +89 other locations
Elotuzumab in Combination With Carfilzomib Lenalidomide and Dexamethasone (E-KRd) Versus KRd in MM

Of the next-generation compounds, the monoclonal antibodies (moAbs) have recently attracted a lot of interest in MM. The anti-SLAMF7 directed moAb elotuzumab has completed phase III trials in MM patients. One phase III trial in MM patients with one to three prior lines of therapy compared elotuzumab-Rd with standard Rd. …

Vivantes Klinikum Spandau
 (5.9 away) Contact site
  • 8 views
  • 03 Mar, 2021
  • +57 other locations
A Study to Evaluate the Safety Tolerability and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis

This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS) and to assess the pharmacokinetics (PK) of BIIB017 in pediatric participants with RRMS in Part 1. In Part 2, the study will evaluate the long-term safety of BIIB017 and further …

relapsing multiple sclerosis
interferon
magnetic resonance imaging brain
Research Site
 (8.8 away) Contact site
  • 109 views
  • 02 Apr, 2021
  • +69 other locations
A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adult Participants With Moderate to Severe Ulcerative Colitis

This phase 2b study is designed to have all subjects go into a 12 week induction period to compare different doses of study drug against placebo. After induction is complete all subjects will receive active therapy for 40 weeks, followed by a 12 week follow up period.

Deutsches Rotes Kreuz Schwesternschaft Berlin Gemeinn tzige Krankenhaus GmbH
 (8.3 away) Contact site
  • 32 views
  • 01 Jun, 2021
  • +240 other locations
A Study of Baricitinib (LY3009104) in Participants From 2 Years to Less Than 18 Years Old With Active JIA-Associated Uveitis or Chronic Anterior Antinuclear Antibody-Positive Uveitis

The reason for this study is to see if the study drug baricitinib given orally is safe and effective in participants with active juvenile idiopathic arthritis (JIA)-associated uveitis or chronic anterior antinuclear antibody-positive uveitis from 2 years to less than 18 years old.

corticosteroid therapy
ly3009104
steroid therapy
adalimumab
methotrexate
Charit Universit tsmedizin Berlin
 (8.8 away) Contact site
  • 9 views
  • 17 Jun, 2021
  • +39 other locations
A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer Compared to Nab-paclitaxel+Gemcitabine Treatment

The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxaliplatin compared to nab-paclitaxel + gemcitabine treatment in improving the overall survival of patients not previously treated for …

Charit - Universitaetsmedizin Berlin
 (8.8 away) Contact site
  • 31 views
  • 12 Jun, 2021
  • +271 other locations