Forchheim, Germany Clinical Trials

A listing of Forchheim, Germany clinical trials actively recruiting patients volunteers.

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Found 46 clinical trials
Efficacy and Safety of Nefecon in Patients With Primary IgA (Immunoglobulin A) Nephropathy

The overall aim of the study is to evaluate the efficacy, safety, and tolerability of Nefecon 16 mg per day in the treatment of patients with primary IgAN (Immunoglobulin A nephropathy) at risk of progressing to end-stage renal disease (ESRD), despite maximum tolerated treatment with renin-angiotensin system (RAS) blockade using …

Universitaetsklinikum Erlangen, Medizinisches Klinik 4, Ulmenweg 18
 (8.7 away) Contact site
  • 735 views
  • 26 Jan, 2021
  • +153 other locations
Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017

The understanding of acute lymphoblastic leukemia (ALL) in childhood and adolescence has largely changed due to extensive genetic research in recent years: ALL is now considered to be a very heterogeneous disease group. The leukemia cells present themselves with quite differently activated regulatory mechanisms of the malignant phenotype. The introduction …

mercaptopurine
pegaspargase
thioguanine
acute leukemia
dexamethasone
Universitaets - Kinderklinik
 (8.7 away) Contact site
  • 562 views
  • 26 Jan, 2021
  • +167 other locations
Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

The primary objective of Part 1 of the study is to determine if BIIB093 improves functional outcome at Day 90 as measured by the modified Rankin Scale (mRS) when compared with placebo in participants with Large Hemispheric Infarction (LHI). The secondary objectives of Part 1 of the study are to …

thrombectomy
ischemic stroke
infarct
MRI
glibenclamide
Research Site
 (9.4 away) Contact site
  • 213 views
  • 13 Jun, 2021
  • +221 other locations
PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation

Atrial fibrillation (AF) is the most common form of irregular heart rhythm. In people with AF, blood clots often form in the heart, which can travel to the brain. Blockage of brain arteries by these clots is a major cause of stroke. This type of stroke is called an ischaemic …

apixaban oral tablet
dabigatran
vascular disease
apixaban
edoxaban
University Hospital Erlangen
 (9.4 away) Contact site
  • 13 views
  • 25 Feb, 2021
  • +27 other locations
Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

A global study to evaluate peri-operative pembrolizumab with chemotherapy versus placebo to pembrolizumab plus chemotherapy in cisplatin eligible patients.

Universitaetsklinikum Erlangen ( Site 0505)
 (8.7 away) Contact site
  • 58 views
  • 09 Jun, 2021
  • +190 other locations
A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCON

This international, multi-center, randomized, double-blind, placebo-controlled Phase 3 trial will study the safety, tolerability, and efficacy of bardoxolone methyl in qualified patients with ADPKD. Approximately 300 patients will be enrolled.

diastolic blood pressure
systolic blood pressure
cyst
Universit tsklinikum Erlangen, Med4
 (8.7 away) Contact site
  • 270 views
  • 09 Jun, 2021
  • +125 other locations
Long-Term PF-06651600 for the Treatment of Alopecia Areata

This is a global Phase 3 study to evaluate the safety and effectiveness of an investigational study drug (called PF-06651600) in adults and adolescents (12 years and older) who have alopecia areata. Eligible patients from the prior studies B7931005 (NCT02974868) and B7981015 (NCT03732807) will have an opportunity to enroll as …

pf-06651600
androgenic alopecia
alopecia totalis
alopecia universalis
areata alopecia
Universitaetsklinikum Erlangen
 (8.7 away) Contact site
  • 1560 views
  • 13 Jun, 2021
  • +175 other locations
Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS)

The purpose of this study is to demonstrate superiority of secukinumab at Week 16, based on Hidradenitis Suppurativa Clinical Response (HiSCR) rates versus placebo, along with the maintenance of efficacy of secukinumab at Week 52 in subjects with moderate to severe HS. Moreover, this study will also assess the safety …

hidradenitis
abscess
antiseptics
secukinumab
Novartis Investigative Site
 (8.7 away) Contact site
  • 909 views
  • 10 Jun, 2021
  • +112 other locations
Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term Treatment of Two Dose Regimes of Secukinumab in Subjects With Hidradenitis Suppurativa

The purpose of this extension study is to evaluate maintenance of HiSCR response at Week 104 in either continuous or interrupted therapy (using a randomized withdrawal period) of two dose regimens and to assess long-term efficacy, safety and tolerability of secukinumab in subjects with moderate to severe hidradenitis suppurativa completing …

expanded access trial
hidradenitis
secukinumab
Novartis Investigative Site
 (8.7 away) Contact site
  • 45 views
  • 11 Jun, 2021
  • +168 other locations
Efficacy of Secukinumab Compared to Ustekinumab in Adults With Active Psoriatic Arthritis and Failure of TNF -Inhibitor Treatment

The purpose of this study is to compare the safety and efficacy of secukinumab and ustekinumab in patients with active psoriatic arthritis who showed failure to previous TNF-inhibitor treatment

psoriatic plaque
ustekinumab
arthritis
rheumatoid factor
plaque psoriasis
Novartis Investigative Site
 (8.7 away) Contact site
  • 0 views
  • 04 Jun, 2021
  • +24 other locations