Forchheim, Germany Clinical Trials

A listing of Forchheim, Germany clinical trials actively recruiting patients volunteers.

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Found 46 clinical trials
Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

The primary objective of Part 1 of the study is to determine if BIIB093 improves functional outcome at Day 90 as measured by the modified Rankin Scale (mRS) when compared with placebo in participants with Large Hemispheric Infarction (LHI). The secondary objectives of Part 1 of the study are to …

thrombectomy
ischemic stroke
glyburide
infarct
glibenclamide
Research Site
 (9.4 away) Contact site
  • 213 views
  • 21 Jun, 2021
  • +221 other locations
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizumab-based parent studies who roll-over into this extension study. This study will consist of three phases: 1) First Course Phase, 2) Survival Follow-up Phase or 3) Second Course Phase. …

pembrolizumab
metastasis
mk-3475
major surgery
Universit tsklinikum Erlangen ( Site 2408)
 (8.7 away) Contact site
  • 510 views
  • 20 Jun, 2021
  • +263 other locations
Efficacy and Safety of Nefecon in Patients With Primary IgA (Immunoglobulin A) Nephropathy

The overall aim of the study is to evaluate the efficacy, safety, and tolerability of Nefecon 16 mg per day in the treatment of patients with primary IgAN (Immunoglobulin A nephropathy) at risk of progressing to end-stage renal disease (ESRD), despite maximum tolerated treatment with renin-angiotensin system (RAS) blockade using …

Universitaetsklinikum Erlangen, Medizinisches Klinik 4, Ulmenweg 18
 (8.7 away) Contact site
  • 735 views
  • 26 Jan, 2021
  • +153 other locations
Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017

The understanding of acute lymphoblastic leukemia (ALL) in childhood and adolescence has largely changed due to extensive genetic research in recent years: ALL is now considered to be a very heterogeneous disease group. The leukemia cells present themselves with quite differently activated regulatory mechanisms of the malignant phenotype. The introduction …

mercaptopurine
methotrexate
adult t-cell leukemia/lymphoma
etoposide
acute leukemia
Universitaets - Kinderklinik
 (8.7 away) Contact site
  • 562 views
  • 26 Jan, 2021
  • +167 other locations
Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

A global study to evaluate peri-operative pembrolizumab with chemotherapy versus placebo to pembrolizumab plus chemotherapy in cisplatin eligible patients.

Universitaetsklinikum Erlangen ( Site 0505)
 (8.7 away) Contact site
  • 58 views
  • 09 Jun, 2021
  • +190 other locations
PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation

Atrial fibrillation (AF) is the most common form of irregular heart rhythm. In people with AF, blood clots often form in the heart, which can travel to the brain. Blockage of brain arteries by these clots is a major cause of stroke. This type of stroke is called an ischaemic …

dabigatran
brain imaging
vascular disease
apixaban oral tablet
clot
University Hospital Erlangen
 (9.4 away) Contact site
  • 13 views
  • 25 Feb, 2021
  • +27 other locations
A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCON

This international, multi-center, randomized, double-blind, placebo-controlled Phase 3 trial will study the safety, tolerability, and efficacy of bardoxolone methyl in qualified patients with ADPKD. Approximately 300 patients will be enrolled.

systolic blood pressure
cyst
diastolic blood pressure
Universit tsklinikum Erlangen, Med4
 (8.7 away) Contact site
  • 270 views
  • 14 Jun, 2021
  • +125 other locations
Long-Term PF-06651600 for the Treatment of Alopecia Areata

This is a global Phase 3 study to evaluate the safety and effectiveness of an investigational study drug (called PF-06651600) in adults and adolescents (12 years and older) who have alopecia areata. Eligible patients from the prior studies B7931005 (NCT02974868) and B7981015 (NCT03732807) will have an opportunity to enroll as …

areata alopecia
alopecia universalis
alopecia
androgenic alopecia
alopecia totalis
Universitaetsklinikum Erlangen
 (8.7 away) Contact site
  • 1560 views
  • 13 Jun, 2021
  • +175 other locations
Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC

The GLORIA study is a Phase III, randomized, open-label study to prospectively evaluate the efficacy and safety of adagloxad simolenin (OBI 822)/OBI-821 in the adjuvant treatment of patients with high risk, early stage Globo-H Positive TNBC.

serum total bilirubin
erbb2
HER2
taxane
invasive breast cancer
Universitaetsklinikum Erlangen
 (8.7 away) Contact site
  • 309 views
  • 10 May, 2021
  • +125 other locations
Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

The purpose of this study is to assess the efficacy and safety of pembrolizumab (MK-3475) versus placebo in combination with neoadjuvant (pre-surgery) chemotherapy and adjuvant (post-surgery) endocrine therapy in the treatment of adults who have high-risk early-stage estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+/HER2-) breast cancer. The primary …

core needle biopsy
erbb2
EGFR
doxorubicin
HER2
Universitaetsklinikum Erlangen ( Site 1001)
 (8.7 away) Contact site
  • 188 views
  • 18 Jun, 2021
  • +285 other locations