Forchheim, Germany Clinical Trials

A listing of Forchheim, Germany clinical trials actively recruiting patients volunteers.

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Found 46 clinical trials
Study of IMMU-132 in HR+/HER2- MBC (TROPICS-02)

This is an open-label, randomized, multicenter Phase 3 study to compare the efficacy and safety of Sacituzumab Govitecan versus TPC in subjects with metastatic or locally recurrent inoperable HR+/HER2- MBC, after failure of at least 2, and no more than 4, prior chemotherapy regimens for metastatic disease.

metastasis
HER2
cancer chemotherapy
kidney function tests
capecitabine
Universit tsklinikum Erlangen
 (8.7 away) Contact site
  • 66 views
  • 05 Oct, 2020
  • +104 other locations
Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Phase III, double-blind, randomised study assessing the efficacy of capivasertib + fulvestrant vs placebo + fulvestrant for the treatment of patients with locally advanced (inoperable) or metastatic HR+/HER2- breast cancer following recurrence or progression on or after AI therapy.

Research Site
 (8.7 away) Contact site
  • 50 views
  • 28 Dec, 2020
  • +198 other locations
Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC

A Global Study to Determine the Efficacy and Safety of Durvalumab in Combination with Gemcitabine+Cisplatin for Neoadjuvant Treatment and Durvalumab Alone for Adjuvant Treatment in Patients with Muscle-Invasive Bladder Cancer

Research Site
 (8.7 away) Contact site
  • 147 views
  • 17 Jan, 2021
  • +245 other locations
A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety

The purpose of the study is to show the blood pressure lowering effect of aprocitentan, a new drug, when added to other anti-hypertensive drugs of patients with difficult to control (resistant) high blood pressure (hypertension), and to show that blood pressure reduction is kept for long period of time.

antihypertensive drugs
Universit tsklinikum Erlangen Klinische Forschungsstation (CRC)
 (8.7 away) Contact site
  • 1409 views
  • 25 Dec, 2020
  • +345 other locations
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-PD-(L) 1 agent (cohort 1) …

transitional cell carcinoma
pembrolizumab
adjuvant chemotherapy
docetaxel
renal function
Friedrich-Alexander Universitaet Urologische Universitaetskl
 (8.7 away) Contact site
  • 271 views
  • 12 Oct, 2020
  • +522 other locations
Efficacy and Safety of Nefecon in Patients With Primary IgA (Immunoglobulin A) Nephropathy

The overall aim of the study is to evaluate the efficacy, safety, and tolerability of Nefecon 16 mg per day in the treatment of patients with primary IgAN (Immunoglobulin A nephropathy) at risk of progressing to end-stage renal disease (ESRD), despite maximum tolerated treatment with renin-angiotensin system (RAS) blockade using …

Universitaetsklinikum Erlangen, Medizinisches Klinik 4, Ulmenweg 18
 (8.7 away) Contact site
  • 735 views
  • 25 Oct, 2020
  • +153 other locations
A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer

A phase III multi-center, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as adjuvant treatment in patients with HR+/HER2- Early Breast Cancer

Novartis Investigative Site
 (8.7 away) Contact site
  • 211 views
  • 25 Oct, 2020
  • +343 other locations
Linerixibat Long-term Safety and Tolerability Study

This is an open-label, non-comparator, global, multi-center, long-term safety study for evaluating safety and tolerability of linerixibat in participants with cholestatic pruritus in primary biliary cholangitis (PBC) who participated in a prior eligible clinical trial with linerixibat. Participants will be administered with 90 milligrams (mg) linerixibat orally twice daily. The …

cholangitis
cholestatic pruritus
GSK Investigational Site
 (8.7 away) Contact site
  • 0 views
  • 29 Dec, 2020
  • +20 other locations
Dendritic Cells Plus Autologous Tumor RNA in Uveal Melanoma

Patients suffering from uveal melanoma (typed positive for monosomy 3 and without evidence for metastases) will be vaccinated over a period of 2 years with Dendritic Cell loaded with autologous Tumor RNA. 200 patients will be included. The Trial is an open multicenter Phase III Trial.

metastasis
therapeutic autologous dendritic cells
University Hospital Department of Ophtalmology
 (8.7 away) Contact site
  • 16 views
  • 12 Jan, 2020
  • +9 other locations
Dasatinib Holiday for Improved Tolerability

Treatment optimization for patients with chronic myeloid leukemia (CML) with treatment nave disease (1st line) and patients with resistance or intolerance against alternative Abl-Kinase Inhibitors (2nd line) (DasaHIT Trial (Dasatinib Holiday for Improved Tolerability))

potassium
ponatinib
hydroxyurea
imatinib
dasatinib
Gemeinschaftspraxis Erlangen
 (9.5 away) Contact site
  • 11 views
  • 16 Sep, 2020
  • +79 other locations