Forchheim, Germany Clinical Trials

A listing of Forchheim, Germany clinical trials actively recruiting patients volunteers.

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Found 127 clinical trials
The Elixir Bioadaptor vs. The Onyx Stent in De Novo Native Coronary Arteries

The objective of this study is to verify the safety and efficacy of the investigational device (ELX1805J) for the treatment of ischemic heart disease due to de novo, native coronary artery lesions

Universitatsklinikum Erlangen
 (8.7 away) Contact site
  • 25 Apr, 2021
  • +35 other locations
A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Patients With Metastatic Colorectal Cancer

This is a global, randomized, double-blind, placebo-controlled, multicenter phase 3 clinical trial to compare the efficacy and safety of fruquintinib plus best supportive care (BSC) versus placebo plus BSC in patients with refractory metastatic colorectal cancer (mCRC). 687 subjects will be randomized to one of the following treatment arms in …

microsatellite instability high
vascular endothelial growth factor
adjuvant therapy
Universitaetsklinikum Erlangen
 (8.7 away) Contact site
  • 30 Apr, 2021
  • +138 other locations
Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term Treatment of Two Dose Regimes of Secukinumab in Subjects With Hidradenitis Suppurativa

The purpose of this extension study is to evaluate maintenance of HiSCR response at Week 104 in either continuous or interrupted therapy (using a randomized withdrawal period) of two dose regimens and to assess long-term efficacy, safety and tolerability of secukinumab in subjects with moderate to severe hidradenitis suppurativa completing …

expanded access trial
Novartis Investigative Site
 (8.7 away) Contact site
  • 11 Jun, 2021
  • +168 other locations
SPYRAL DYSTAL Renal Denervation Global Clinical Study

The objective of this single arm interventional study is to determine if renal denervation performed in the distal main and first order branch renal arteries is as effective in reducing blood pressure as the procedural approach used in the SPYRAL HTN-OFF MED clinical study.

systolic blood pressure
antihypertensive drugs
ambulatory blood pressure monitoring
renal angiogram
Universitaetsklinikum Erlangen
 (9.4 away) Contact site
  • 11 May, 2021
  • +11 other locations
Ponatinib With Chemotherapy in Pediatric Participants With Relapsed Resistant or Intolerant Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) or Have the T315I Mutation

The purpose of the study is to determine the recommended phase 2 dose (RP2D) of ponatinib (tablet and age-appropriate formulation [AAF]) in combination with chemotherapy in Phase 1 and the efficacy of ponatinib in combination with chemotherapy as measured by the rate of complete remission (CR) at the end of …

Universitaetsklinik Erlangen Kinder- und Jugendklinik
 (8.7 away) Contact site
  • 15 May, 2021
  • +51 other locations
A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer

DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with other anti-cancer agents in patients with HER2-positive Metastatic Breast Cancer

Research site
 (8.7 away) Contact site
  • 04 Jun, 2021
  • +69 other locations
Radium-223 Dichloride Long-term Follow-up Program

Patients will be followed up in this study after prior treatment with BAY88-8223 / Radium-223 dichloride / Xofigo .

 (8.7 away) Contact site
  • 29 May, 2021
  • +130 other locations
A Multicentre European Study to Evaluate Granulox Used in the Treatment Pathway of Predominantly Chronic Venous Leg Ulcers (VLUs).

The investigation is designed as an open label, randomized, prospective, assessor blinded, multi centre investigation. 254 evaluable subjects will be randomized to either standard of care group or standard of care with Granulox added as an adjunct therapy in predominantly venous leg ulcer subjects. Standard of care wound management will …

wound care
systemic steroids
immunosuppressive agents
compression therapy
leg ulcer
University Hospital Erlangen
 (9.4 away) Contact site
  • 08 May, 2021
  • +36 other locations
Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss Without PIK3CA Mutation

The purpose of this study is to determine whether treatment with alpelisib in combination with nab-paclitaxel is safe and effective in subjects with advanced triple negative breast cancer (aTNBC) who carry either a PIK3CA mutation (Study Part A) or have PTEN loss without PIK3CA mutation (Study Parts B1 and B2)

breast cancer
Novartis Investigative Site
 (8.7 away) Contact site
  • 02 Jun, 2021
  • +135 other locations
Study of Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria Patients Who Completed a Previous Study With Ligelizumab

The purpose of this extension study is to establish efficacy and safety of ligelizumab. This will be assessed in adult and adolescent chronic spontaneous urticaria (CSU) patients who have completed a preceding ligelizumab study and have relapsed, following treatment in these preceding studies, despite standard of care H1-antihistamine (H1-AH) treatment. …

Novartis Investigative Site
 (8.7 away) Contact site
  • 09 Jun, 2021
  • +215 other locations