Forchheim, Germany Clinical Trials

A listing of Forchheim, Germany clinical trials actively recruiting patients volunteers.

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Found 127 clinical trials
Early Versus Emergency Left Ventricular Assist Device Implantation in Patients Awaiting Cardiac Transplantation

The aim of the study is to assess whether, in patients who are listed for cardiac transplantation in transplantable (T) status, early implantation of a left ventricular assist device is superior to the current therapeutic strategy of medical heart failure therapy and assist device implantation only after serious deterioration of …

Universit tsklinikum Erlangen - Herzchirurgische Klinik
 (8.7 away) Contact site
  • 31 views
  • 23 Jan, 2021
  • +42 other locations
Dendritic Cells Plus Autologous Tumor RNA in Uveal Melanoma

Patients suffering from uveal melanoma (typed positive for monosomy 3 and without evidence for metastases) will be vaccinated over a period of 2 years with Dendritic Cell loaded with autologous Tumor RNA. 200 patients will be included. The Trial is an open multicenter Phase III Trial.

metastasis
therapeutic autologous dendritic cells
University Hospital Department of Ophtalmology
 (8.7 away) Contact site
  • 16 views
  • 09 May, 2021
  • +11 other locations
ENDURE - Efficacy and Safety of AOP2014 With CML Patients in Remission

A randomized, open-label assessor blinded, multi-center, controlled phase II Trial to evaluate the efficacy of AOP2014 administered bi-weekly subcutaneously (s.c.) in preventing molecular relapse (loss of MMR) in CML patients, who discontinue ABL tyrosine kinase inhibitor therapy (TKI) in deep molecular remission of MR4 or better (MR4.5, or MR5).

Universit tsklinikum Erlangen
 (8.7 away) Contact site
  • 22 views
  • 25 Jan, 2021
  • +47 other locations
Dasatinib Holiday for Improved Tolerability

Treatment optimization for patients with chronic myeloid leukemia (CML) with treatment nave disease (1st line) and patients with resistance or intolerance against alternative Abl-Kinase Inhibitors (2nd line) (DasaHIT Trial (Dasatinib Holiday for Improved Tolerability))

bosutinib
potassium
hydroxyurea
imatinib
nilotinib
Gemeinschaftspraxis Erlangen
 (9.5 away) Contact site
  • 11 views
  • 05 Feb, 2021
  • +79 other locations
Modulation of Tissue Sodium in Hemodialysis Patients

Salt (NaCl) intake is implicated in causing hypertension and cardiovascular disease, the commonest cause of death worldwide. The investigators recently established that Na+ is stored in tissues, bound to glycosaminoglycans (GAGs) in skin and muscle. The resulting local hypertonicity leads to immune cell-driven induction of local tissue electrolyte clearance via …

Nephrology Department, University Hospital Erlangen
 (8.7 away) Contact site
  • 9 views
  • 27 Jan, 2021
  • 1 location
Radiotherapy With Double Checkpoint Blockade of Locally Advanced HNSCC

First-line treatment of locally advanced HNSCC with double checkpoint blockade and radiotherapy dependent on intratumoral CD8+ T cell Infiltration.

Erlangen, Universit tsklinikum Strahlenklinik
 (8.7 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +13 other locations
Gluten Free Diet in IBS

Patients with irritable bowel syndrome (IBS) often benefit from dietary changes. The effect of a gluten-free diet (GFD) on clinical symptom improvement and psychological well-being will be checked in patients with IBS. In addition, the stimulatory potential of gluten on peripheral blood monocytes will be determined. Responders will be provoked …

Department of Medicine 1, Hector Center for Nutrition, Exercise and Sports, Friedrich-Alexander-University Erlangen-Nuremberg
 (9.5 away) Contact site
  • 0 views
  • 03 Feb, 2021
  • 1 location
Effect of Evolocumab on Vascular Function

This is a phase IV, randomized (1:1), prospective, double-blind, placebo controlled, parallel-group, single center study at the Clinical Research Unit (CRC) of the Department of Nephrology and Hypertension, with its two separate locations: Nrnberg, Kreuzburger Str. 2, 90471 Nrnberg, and Erlangen, Ulmenweg 18, 91054 Erlangen The results of this study …

angiography
fasting
coronary artery stenosis
peripheral vascular disease
stroke
Clinical Research Center, Department of Nephrology and Hypertension, University of Erlangen-Nuremberg
 (8.7 away) Contact site
  • 0 views
  • 12 May, 2021
  • 1 location
A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

The purpose of study is to compare bladder intact-event free survival (BI-EFS) in participants receiving TAR-200 in combination with cetrelimab versus concurrent chemoradiotherapy.

bladder tumor
conjugated bilirubin
radical cystectomy
gilbert's syndrome
neutrophil count
Waldkrankenhaus St. Marien -Urologische Universit tsklinik
 (8.7 away) Contact site
  • 0 views
  • 03 Jun, 2021
  • +301 other locations
Efficacy and Safety of Brodalumab Compared With Guselkumab in the Treatment of Plaque Psoriasis After Inadequate Response to Ustekinumab

The trial investigates the efficacy and safety of brodalumab against guselkumab in treatment for patients with moderate-to-severe plaque psoriasis who still have some remaining symptoms after ustekinumab treatment.

guselkumab
ustekinumab
plaque psoriasis
LEO Pharma Investigational Site
 (8.7 away) Contact site
  • 0 views
  • 02 Jun, 2021
  • +70 other locations