Forchheim, Germany Clinical Trials

A listing of Forchheim, Germany clinical trials actively recruiting patients volunteers.

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Found 129 clinical trials
Hyper-Thermia Enhanced Anti-tumor Efficacy of Trabectedin

This trial compares trabectedin alone to trabectedin in combination with regional hyperthermia in patients with high-risk soft tissue sarcoma. The study is designed to demonstrate a significant benefit for sarcoma-therapy by adding regional hyperthermia.

ifosfamide
soft tissue sarcoma
gastrointestinal stromal tumor
trabectedin
neutrophil count
Universit tsklinikum Erlangen
 (8.7 away) Contact site
  • 82 views
  • 22 Jan, 2021
  • +6 other locations
Frontline Asciminib Combination in Chronic Phase CML

Adult male and female patients with newly diagnosed Philadelphia chromosome positive (Ph+) and/or BCR-ABL1 positive CML can be included in the study until 3 months after diagnosis. A <4 week pretreatment with hydroxyurea is permitted. Patients treated for <6 weeks with nilotinib 300 mg BID, imatinib 400 mg QD, or …

imatinib
chronic phase chronic myeloid leukemia
philadelphia chromosome
hydroxyurea
dasatinib
Universit tsklinikum Erlangen
 (8.7 away) Contact site
  • 0 views
  • 25 Aug, 2021
  • +36 other locations
Protein Supplementation and HIIT: Impact on Cardiorespiratory Fitness

The aim of this study is to investigate the effects of an 8-week high-intensity interval training (HIIT) or HIIT plus resistance training program combined with post-exercise protein supplementation on cardiorespiratory fitness and cardiometabolic risk indices in previously untrained individuals.

Department of Medicine 1, Hector Center for Nutrition, Exercise and Sports, Friedrich-Alexander-University Erlangen-Nuremberg
 (9.5 away) Contact site
  • 0 views
  • 24 Jan, 2021
  • 1 location
A Study to Test Long-term Treatment With Spesolimab in Patients With Fistulising Crohn's Disease Who Took Part in Previous Trials

The main objectives of this study are to evaluate the long-term safety of spesolimab in patients with perianal fistulising Crohn's disease who have completed treatment in parent trials and to evaluate the long-term efficacy of spesolimab in patients with perianal fistulising Crohn's disease, who have completed treatment in parent trials

crohn's disease
fistulising crohn's disease
remission
Universit tsklinikum Erlangen
 (8.7 away) Contact site
  • 0 views
  • 17 Sep, 2021
  • +2 other locations
BIO|CONCEPT.ECG-Library

The aim of the study is to collect data from surface ECGs by using Holter ECG recordings from patients with different forms of diagnosed arrhythmias and/or specific ECG characteristics from heart diseases to support the development of new sensing and detection algorithms for implants.

coronary disease
ventricular extrasystoles
infarct
depression
holter monitor
Universit tsklinikum Erlangen
 (9.4 away) Contact site
  • 3 views
  • 10 Sep, 2021
  • +8 other locations
Tissue K+ in Primary Hyperaldosteronism

Recent human studies found tissue sodium storage in patients with hyperaldosteronism that could be detected non-invasively by 23Na-MRI. Tissue sodium accumulation could be mobilized upon treatment of hyperaldosteronism. Besides, former animal studies applying chemical electrolyte analysis indicate that this aldosterone induced sodium storage might be accompanied by intracellular potassium loss. …

electrolytes
aldosterone
potassium
hyperaldosteronism
Nephrology Department, University Hospital Erlangen
 (8.7 away) Contact site
  • 0 views
  • 27 Jan, 2021
  • +1 other locations
Evaluation of Therapeutic Response in Spinal Muscular Atrophy Using Multispectral Optoacoustic Tomography (MSOT) and Magnetic Resonance Imaging (MRI)

This study aims to refine the capability of Multispectral Optoacoustic Tomography (MSOT) and Magnet Resonance Imaging (MRI) to characterise the molecular composition of muscle tissue non-invasively and to evaluate the therapeutic response in patients with spinal muscular atrophy (SMA) over time.

spinal muscular atrophy type i
optoacoustic tomography
muscle atrophy
spinraza
University Hospital Erlangen
 (8.7 away) Contact site
  • 0 views
  • 23 Jan, 2021
  • 1 location
TCR Modified T Cells MDG1011 in High Risk Myeloid and Lymphoid Neoplasms

This is a multicentre, non-randomized, open-label, Phase I/II clinical trial of MDG1011, an investigational medicinal product (IMP), consisting of patient-derived autologous T cells, persistently transduced with a Preferentially Expressed Antigen in Melanoma (PRAME)-specific human leukocyte antigen (HLA)-A*02:01-restricted T cell receptor (TCR).

Clinical trial site 102
 (9.4 away) Contact site
  • 3 views
  • 23 Jan, 2021
  • +9 other locations
Radiotherapy With Pembrolizumab in Metastatic HNSCC

Randomized phase II study of immune stimulation with Pembrolizumab and radiotherapy in second line therapy of metastatic head and neck squamous cell carcinoma.

pembrolizumab
squamous cell carcinoma
measurable disease
metastatic head and neck squamous cell carcinoma
Erlangen, Universit tsklinikum Strahlenklinik
 (8.7 away) Contact site
  • 4 views
  • 26 Jan, 2021
  • +16 other locations
International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)

The HIT-HGG-2013 trial offers an innovative high-quality diagnostics and science program for children and adolescents >3 years, suffering from one of the following types of high grade gliomas glioblastoma WHO grade IV (GBM) diffuse midlineglioma histone 3 K27M mutated WHO grade IV (DMG) anaplastic astrocytoma WHO grade III (AA) diffuse …

glioblastoma multiforme
malignant glioma
astrocytoma
epilepsy
temozolomide
Universit tsklinikum Erlangen
 (8.7 away) Contact site
  • 44 views
  • 30 Jan, 2021
  • +48 other locations