Forchheim, Germany Clinical Trials

A listing of Forchheim, Germany clinical trials actively recruiting patients volunteers.

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Found 129 clinical trials
Intensive Rhythm Monitoring to Decrease Ischemic Stroke and Systemic Embolism - the Find-AF 2 Study

Patients who have suffered a stroke are having an increased risk of having recurrent stroke in the future. This risk of stroke is increased by atrial fibrillation, which often "comes and goes" (called paroxysmal) and hence escapes routine diagnostics. The hypothesis of Find-AF 2 is that enhanced (evaluation in a …

fibrillation
electrocardiogram
anticoagulation therapy
stroke
embolism
Universit tsklinikum Erlangen
 (8.7 away) Contact site
  • 0 views
  • 17 Sep, 2021
  • +52 other locations
Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss

The purpose of this study is to determine whether treatment with alpelisib in combination with nab-paclitaxel is safe and effective in subjects with advanced triple negative breast cancer (aTNBC) who carry either a PIK3CA mutation (Study Part A) or have PTEN loss (Study Part B1) or PTEN loss without PIK3CA …

PTEN
mammogram
metastasis
paclitaxel
breast cancer
Novartis Investigative Site
 (8.7 away) Contact site
  • 5 views
  • 20 Sep, 2021
  • +153 other locations
Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients

The purpose of this study is to compare the efficacy and safety of eflornithine in combination with lomustine, compared to lomustine taken alone, in treating patients whose anaplastic astrocytoma has recurred/progressed after radiation and temozolomide chemotherapy.

karnofsky performance status
anaplastic astrocytoma
temozolomide
lomustine
flair
Universtaetsklinikum Erlangen - Neurologische Klinik
 (8.7 away) Contact site
  • 0 views
  • 25 May, 2021
  • +119 other locations
SPYRAL HTN-ON MED Study

The purpose of this study is to test the hypothesis that renal denervation decreases blood pressure and is safe when studied in the presence of up to three standard antihypertensive medications.

24-hour ambulatory blood pressure monitoring
renal angiogram
systolic blood pressure
antihypertensive drugs
ambulatory blood pressure monitoring
Universit tsklinikum Erlangen
 (8.7 away) Contact site
  • 0 views
  • 17 Sep, 2021
  • +75 other locations
Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis (PBC) is a serious, life-threatening, bile acid related liver disease of unknown cause. Without treatment, it frequently progresses to liver fibrosis and eventual cirrhosis requiring liver transplantation or resulting in death. The investigational drug, Obeticholic Acid (OCA) is a modified bile acid and FXR agonist that is …

obeticholic acid
immune globulin
fibrosis
cholangitis
chenodeoxycholic acid
Friedrich-Alexander-Uniersitat Erlangen
 (8.7 away) Contact site
  • 402 views
  • 27 May, 2021
  • +322 other locations
Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis

To evaluate the safety and efficacy of fingolimod vs. interferon beta-1a i.m. in pediatric patients with multiple sclerosis (MS)

MRI
fingolimod
interferon
Novartis Investigative Site
 (8.7 away) Contact site
  • 72 views
  • 22 Sep, 2021
  • +99 other locations
Study to Assess Efficacy and Safety of Cx601 Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)

The purpose of this study is to evaluate the combined remission of complex perianal fistulas, defined as the clinical assessment at Week 24 of closure of all treated external openings that were draining at baseline despite gentle finger compression, and absence of collections greater than (>) 2 centimeter (cm) (in …

tumour necrosis
infliximab
endoscopy
diarrhea
crohn's disease
Universitatsklinikum Erlangen
 (8.7 away) Contact site
  • 202 views
  • 28 May, 2021
  • +177 other locations
A Trial to Evaluate the Safety and Efficacy of CLDN6 CAR-T +/- CLDN6 RNA-LPX

This is a Phase I/IIa, FIH, open-label, multicenter, dose escalation trial with expansion cohorts to evaluate safety and preliminary efficacy of CLDN6 CAR-T +/- CLDN6 RNA-LPX in patients with CLDN6-positive relapsed or refractory advanced solid tumors.

kidney function test
measurable disease
solid tumor
Universit tsklinikum Erlangen - H matologie & Intrinsische Onkologie - Medizinische Klinik 5
 (8.7 away) Contact site
  • 1 views
  • 23 Jun, 2021
  • +5 other locations
Tofacitinib for Reduction of Spinal Inflammation in Patients With Psoriatic ArthritiS PresenTing With Axial InvOlvement

To evaluate the efficacy of Tofacitinib in reducing inflammation in the sacroiliac joints and spine on magnetic resonance imaging (MRI) in patients with active Psoriatic Arthritis (PsA) with axial Involvement (BASDAI [Bath Ankylosing Spondylitis Disease Activity Index] 4 and total backpain 4 despite treatment with NSAIDs plus evidence of active …

arthritis
NSAID
spondylitis
steroidal anti-inflammatory drugs
ankylosing spondylitis
Uniklinikum, Med. Klinik 3
 (8.7 away) Contact site
  • 0 views
  • 05 Feb, 2021
  • +18 other locations
Influence of Probiotics on Clinical Parameters the Oral Microbiome and the Immune System During an Orthodontic Treatment in Adult Patients

Orthodontic treatment with fixed appliances can be necessary to correct malocclusions in adolescence or adulthood. It its known that orthodontic treatment induces aseptic pseudo-inflammatory reactions. However, studies could show that an increase of certain inflammatory cytokines during orthodontic treatment correlated with a higher risk of root resorption. Moreover, it has …

Department of Orthodontics and Orofacial Orthopedics
 (8.7 away) Contact site
  • 0 views
  • 26 Jan, 2021
  • 1 location