Verdun-sur-le-doubs, France
A Study to Investigate Tonlamarsen for the Treatment of Adults With Uncontrolled Hypertension
Phase
2Span
141 weeksSponsor
Kardigan, Inc.Gurnee, Illinois
Recruiting
A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis
Phase
2Span
163 weeksSponsor
SanofiGurnee, Illinois
Recruiting
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
The protocol consists of 2 studies. Study 1 includes induction and maintenance treatment, and Study 2 includes only induction treatment. Each study has its own hypotheses and outcome measures that will be assessed independently.
Phase
3Span
284 weeksSponsor
Merck Sharp & Dohme LLCGurnee, Illinois
Recruiting
A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Crohn's Disease.
Phase
2Span
233 weeksSponsor
SanofiGurnee, Illinois
Recruiting
A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis
Phase
2Span
183 weeksSponsor
Boehringer IngelheimGurnee, Illinois
Recruiting
A Study to Investigate Weight Management With Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Adults With Obesity or Overweight
Phase
2Span
119 weeksSponsor
Eli Lilly and CompanyGurnee, Illinois
Recruiting
A Study to Assess the Efficacy and Safety of Induction Therapy With RO7790121 in Participants With Moderately to Severely Active Ulcerative Colitis
Phase
3Span
264 weeksSponsor
Hoffmann-La RocheGurnee, Illinois
Recruiting
A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)
Phase
3Span
265 weeksSponsor
Eli Lilly and CompanyGurnee, Illinois
Recruiting
Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/African American and Hispanic Participants With Elevated Lp(a) and Established ASCVD
CTQJ230A12303 is a randomized, double-blind, placebo-controlled, multi-center, Phase IIIb study to evaluate the efficacy ( measured by reduction of the Lp(a) levels) and safety of pelacarsen (TQJ230) 80mg s.c. QM compared to placebo in US Black/African American and US Hispanic participants, with established atherosclerotic cardiovascular disease (ASCVD) as evidenced by history of coronary heart disease, cerebrovascular disease or symptomatic peripheral artery disease (PAD) and elevated levels of Lp(a).
Phase
3Span
151 weeksSponsor
Novartis PharmaceuticalsGrandwood Park, Illinois
Recruiting
A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial)
The duration per participant will be up to 152 weeks.
Phase
4Span
210 weeksSponsor
SanofiGurnee, Illinois
Recruiting