Toulose, France Clinical Trials

A listing of Toulose, France clinical trials actively recruiting patients volunteers.

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Found 133 clinical trials
HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer

This study is designed to evaluate the antitumor activity of patritumab deruxtecan in participants with metastatic or locally advanced NSCLC with an activating EGFR mutation (exon 19 deletion or L858R) who have received and progressed on or after at least 1 EGFR TKI and 1 platinum-based chemotherapy-containing regimen.

Catalan Institute of Badalona Hospital Germans Trias i Pujol ICO
 (151.9 away) Contact site
  • 0 views
  • 19 Jul, 2021
  • +84 other locations
Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and demonstrate proof-of-concept of the efficacy of terminal complement inhibition in participants with LN (LN Cohort) or IgAN (IgAN Cohort).

angiotensin
immunosuppression
nephropathy
nephritis
proteinuria
Clinical Study Site
 (2.3 away) Contact site
  • 0 views
  • 08 Jul, 2021
  • +29 other locations
Study to Evaluate Adverse Events and Change in Disease Activity With Oral Tablets of Upadacitinib in Adult Participants With Non-Segmental Vitiligo

Vitiligo is a common chronic autoimmune disease that causes the body's immune system to attack its own pigment producing skin cells. This study is to evaluate how safe and effective upadacitinib is in participants with non-segmental vitiligo. Adverse effects and change in disease activity will be assessed. Upadacitinib is being …

Hopital Larrey - CHU de Toulouse /ID# 228196
 (2.0 away) Contact site
  • 0 views
  • 12 Jul, 2021
  • +41 other locations
Trastuzumab Deruxtecan in Participants With HER2-mutated Metastatic Non-small Cell Lung Cancer (NSCLC)

This study was designed to evaluate the safety and efficacy of trastuzumab deruxtecan in HER2-mutated metastatic non-small cell lung cancer (NSCLC) participants who had disease recurrence or progression during/after at least one regimen of prior anticancer therapy (second line or later) that must have contained a platinum-based chemotherapy drug.

erbb2
cancer chemotherapy
HER2
liquid biopsy
lung carcinoma
Hospital Universitario Vall d'Hebron
 (153.9 away) Contact site
  • 0 views
  • 18 Jul, 2021
  • +52 other locations
A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

The purpose of this study is evaluate the efficacy of teclistamab at the recommended Phase 2 dose (RP2D).

multiple myeloma
measurable disease
P le IUC Oncopole CHU
 (0.5 away) Contact site
  • 0 views
  • 31 May, 2021
  • +69 other locations
Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma

The primary purpose of this study is to evaluate the efficacy of LXH254 combinations in previously treated unresectable or metastatic melanoma

NRAS
trametinib
cytotoxic t-lymphocyte antigen 4
metastatic cutaneous melanoma
systemic therapy
Novartis Investigative Site
 (48.5 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +33 other locations
A Study to Test Long-term Treatment With Spesolimab in People With Palmoplantar Pustulosis (PPP) Who Took Part in Previous Studies With Spesolimab

This study is open to people with palmoplantar pustulosis who took part in previous clinical studies of a medicine called spesolimab. Participants who benefited from spesolimab treatment in the previous studies can join this study. The purpose of this study is to find out how safe spesolimab is and whether …

palmoplantar pustulosis
HOP l'Archet
 (289.7 away) Contact site
  • 7 views
  • 25 Jul, 2021
  • +66 other locations
Triple Combination of Pevonedistat and Venetoclax Plus Azacitidine in Adults With Acute Myeloid Leukemia Who Are Unfit for Intensive Chemotherapy

The purpose of this study is to determine whether the combination of pevonedistat + venetoclax + azacitidine improves event-free survival (EFS) compared with venetoclax + azacitidine in patients with newly diagnosed acute myeloid leukemia (AML) who are unfit for intensive chemotherapy.

venetoclax
ejection fraction
direct bilirubin
leukapheresis
gilbert's syndrome
Centre Hospitalier Universitaire de Clermont ferrand
 (169.8 away) Contact site
  • 2 views
  • 16 May, 2021
  • +58 other locations
A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease

The primary purpose of this study is to evaluate the effect of JNJ-63733657 versus placebo on cognitive decline using the Alzheimer's Disease Assessment Scale Cognitive subscale 13-item version (ADAS-Cog13).

alzheimer's disease
cognitive decline
cognitive assessment
dementia
H pital Pellegrin CHU Bordeaux
 (131.5 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +144 other locations
A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors

Researchers are looking for a better way to treat people with solid tumors. Before a treatment can be approved for people to take, researchers do clinical trials to better understand its safety and how it works. In this trial, the researchers want to learn about regorafenib taken together with nivolumab …

Institut Bergoni - Unicancer Nouvelle Aquitaine
 (131.0 away) Contact site
  • 0 views
  • 24 Jul, 2021
  • +42 other locations