Toulose, France Clinical Trials

A listing of Toulose, France clinical trials actively recruiting patients volunteers.

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Found 129 clinical trials
Efficacy of Neoadjuvant Chemotherapy in Terms of DFS in Patients With Localized Digestive Neuroendocrine Carcinomas

NEONEC is a single-phase, phase II study evaluating the efficacy of the 12-month neoadjuvant chemotherapy in patients with locally differentiated digestive NEC. The recommended chemotherapy is based on the current reference combination of platinum (cisplatin or carboplatin) and etoposide (VP16). For anorectal locations, radiochemotherapy is proposed to avoid the morbidity …

positron emission tomography
immunomodulator
who 2017
metastasis
ct scan
CHU Toulouse
 (0.0 away) Contact site
  • 0 views
  • 22 Jun, 2021
  • +8 other locations
ASTX727 and Donor Lymphocyte Infusions After Allogenic Stem Cell Transplantation in Very High Risk MDS or AML Patients

Study of early administration of ASTX727 associated with late Donor Lymphocyte Infusions after allogenic stem cell transplantation in very high risk MDS or AML patients

TP53
blast cells
cell transplantation
IUCT Oncopole - D partement d'h matologie - Service de greffe de cellules souches h matopo tiques
 (2.3 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +13 other locations
Darbepoetin Alpha in Myelodysplastic Syndromes (MDS)

This is an evaluation of the effectiveness of darbepoetin alpha in treating anemia of MDS patients with an International Prognostic Scoring System (IPSS) score of low or intermediate 1.

blood transfusion
refractory cytopenia with multilineage dysplasia
darbepoetin alfa
anemia
chronic myelomonocytic leukemia
CHRU Limoges
 (33.3 away) Contact site
  • 33 views
  • 07 Nov, 2020
  • +22 other locations
Evaluation of Lymphadenectomy and Chemotherapy TIP on Inguinal Lymph Nodes in Squamous Cell Carcinoma of the Penis (AFU-GETUG 25)

Squamous cell carcinoma of the penis is a rare tumor in Europe, whose prognosis and survival are influenced by metastatic lymph node involvement. Its frequency in France is estimated at less than 1% of human cancers. This spread follows a sequential process via the superficial and deep inguinal lymph nodes …

immunomodulator
metastasis
chemotherapy regimen
squamous cell carcinoma
cancer
Institut Claudius Regaud
 (0.5 away) Contact site
  • 15 views
  • 25 Jan, 2021
  • +17 other locations
A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas

INDICATION Metastatic bone sarcomas: conventional high grade osteosarcoma, Ewing sarcoma of bone, intermediate or high-grade chondrosarcomas and chordomas and either bone or soft tissue metastatic CIC-rearranged sarcomas

neutrophil count
lipase
ewing's sarcoma
sarcoma of bone
glomerular filtration rate
ICM Val d'Aurelle
 (119.3 away) Contact site
  • 10 views
  • 11 Apr, 2021
  • +18 other locations
First-line Gemcitabine/Cisplatin +/- Avelumab in Locally Advanced or Metastatic Bladder Carcinoma

This study will assess efficacy (based on response rate) and safety (based on grade 3 severe adverse effects) of the combination Gemcitabine Cisplatin (GC) + anti-PD-L1 (avelumab) in first-line treatment for locally advanced or metastatic urothelial bladder cancer patients, after 6 cycles of treatment (or at 18 weeks if less …

bladder carcinoma
gemcitabine
cisplatin/gemcitabine
metastasis
measurable disease
CHU de Bordeaux
 (131.0 away) Contact site
  • 20 views
  • 26 Jan, 2021
  • +19 other locations
COlchicine for Left VEntricular Remodeling Treatment in Acute Myocardial Infarction

Inflammatory processes have been identified as key mediators of ischemia/ reperfusion injury in ST-segment elevation myocardial infarction. They add additional damage to the myocardium and are associated with clinical adverse events (heart failure and cardiovascular death) and poor myocardial recovery. All the different anti-inflammatory approaches to reduce reperfusion injury have …

chest pain
myocardial infarction
infarct
reperfusion injury
percutaneous coronary intervention
CHU Arnaud de Villeneuve
 (121.2 away) Contact site
  • 3 views
  • 24 May, 2021
  • +14 other locations
Study of Inotuzumab Ozogamicin Combined to Chemotherapy in Older Patients With Philadelphia Chromosome-negative CD22+ B-cell Precursor ALL

The aim of the present EWALL-INO study is to confirm very promising results obtained with a combination of INO and mild chemotherapy in older de novo CD22+ B-ALL patients. For that purpose, safety and efficacy of a weekly INO administration combined to mild-intensity chemotherapy will be evaluated in a cohort …

CH Montpellier
 (121.2 away) Contact site
  • 10 views
  • 25 Jan, 2021
  • +31 other locations
Clinical and Biological Activity of an Anti-PD-L1 (Atezolizumab) in Operable Localised Soft Tissue Sarcomas Patients to be Treated With Radiotherapy

This multicentric, randomised, Phase II trial will use a pick-the-winner design in order to evaluate the clinical and biological activity of atezolizumab when combined with pre-operative or post-operative radiotherapy in STS patients. Following Inform Consent Form (ICF) signature, eligible patients will be randomised (1:1:1) to receive: Arm A: Radiotherapy followed …

Institut Bergonie
 (131.0 away) Contact site
  • 8 views
  • 13 May, 2021
  • +5 other locations
Efficacy Evaluation of Focused HIFU (High Intensity Focused Ultrasound) Therapy in Patients With Localized Intermediate Risk Prostate Cancer

The aim of the focal treatment HIFU is to destroy the cancer without causing side effects in contrast to radical treatments. Radical treatments (surgery or radiation therapy) are the standard therapies for patient with intermediate risk localized prostate cancer and good life expectancy (prostatectomy if life expectancy10 years) By destroying …

prostatectomy
multiparametric magnetic resonance imaging
CHU de Toulouse - H pital de Rangueil
 (3.0 away) Contact site
  • 5 views
  • 26 Jan, 2021
  • +23 other locations