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Toulose, France Clinical Trials

A listing of Toulose, France clinical trials actively recruiting patients volunteers.

RESULTS

Found (94) clinical trials

A Study of Daratumumab Monotherapy in Previously Untreated Patients With Stage 3B Light Chain (AL) Amyloidosis

The current study aims to investigate daratumumab as a monotherapy in patients with stage 3B AL amyloidosis who have not received prior therapy. Approximately 40 subjects will receive primary therapy with daratumumab. Subject participation will include a Screening Phase, a Treatment Phase, a Post-Treatment Observation Phase, and a Long-term Follow-up ...

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Safety and Efficacy of Ponatinib Followed by Imatinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase

TREATMENT PLAN : All eligible patients will be treated: During the induction Phase (Month 1 to Month 6) with ponatinib (30mg/day) single agent; then During the consolidation Phase (Month 7 to Month 36) with imatinib (400mg/day) single agent; then From M36 : Patients with stable MR4.5 (i.e. since at least ...

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A Study of Cusatuzumab Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia Who Are Not Candidates for Intensive Chemotherapy

AML is a heterogeneous disease characterized by uncontrolled clonal expansion of hematopoietic progenitor cells. As the most common form of acute leukemia, AML accounts for the largest number of annual deaths from leukemia. Over 95 percent (%) of AML blasts harvested from newly diagnosed AML participants expressed Cluster of Differentiation ...

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A 4-week Study to Test Different Doses of BI 1265162 in Adolescents and Adults With Cystic Fibrosis Using the Respimat Inhaler - BALANCE - CF 1

The primary objective of this trial is to assess the efficacy, safety and pharmacokinetics of twice daily inhaled doses of BI 1265162 delivered by Respimat inhaler versus placebo in adolescents and adult patients with cystic fibrosis.

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Dulaglutide and Insulin MicrosecretiON in Type 1 Diabetes

Some patients with type 1 diabetes (T1D) can still have some remaining insulin-positive cells in the pancreas and secrete little amounts of insulin. Despite the presence of residual beta cells, the HbA1C levels remain at high levels due to functional defects of insulin secretion associated with glucotoxicity. Previous trials have ...

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Association of Radiochemotherapy and Immunotherapy for the Treatment of Unresectable Oesophageal caNcer

ARION study will randomize 120 patients, in 12 centers in France, according to a ratio 1:1 in the following arm of treatment: Standard and experimental arm: Definitive modulated-intensity radiotherapy will be delivered according to boost integrated technique 5 days a week for 5 weeks at a dose of: 50 Gy ...

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A Study of Neoadjuvant Nivolumab + Abemaciclib or Palbociclib + Anastrozole in Post-Menopausal Women and Men With Primary Breast Cancer

A randomized multi-arm study evaluating the safety and efficacy of abemaciclib or palbociclib and anastrozole with or without nivolumab in participants with ER+/HER2- breast cancer

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Effects of JNJ-53718678 in Adult and Adolescent Participants Who Had a Hematopoietic Stem Cell Transplantation and Who Are Infected With Respiratory Syncytial Virus (RSV)

RSV is recognized as major respiratory pathogen in infants and young children and causes upper and lower respiratory illness among all age groups, often going undiagnosed. Immunocompromised (IC) participants have a reduced ability to combat infection due to an impaired or weakened immune system. Within the IC population, HSCT recipients ...

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Study of DS-8201a an Antibody Drug Conjugate for Advanced Breast Cancer Patients With Biomarkers Analysis

The main objective is to evaluate the anti-tumor activity of DS-8201a in three cohorts of advanced breast cancer patients: Cohort 1: HER2 over-expressing (HER2 IHC3+ or HER2 IHC2+/ISH+) Cohort 2: HER2 low-expressing (IHC1+ or IHC2+/ISH-) Cohort 3: HER2 non-expressing (IHC0+)

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Efficacy and Safety Study of ABX464 as Maintenance Therapy in Patients With Moderate to Severe Ulcerative Colitis

This study is an open-label study aiming at evaluating the long-term safety and the efficacy profile of ABX464 given once a day (o.d) at 50 mg in subjects who have been previously enrolled in the ABX464-103 clinical study (induction study) and who are willing to continue their treatment. All subjects ...

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