St Priest-En-Jarez, France Clinical Trials

A listing of St Priest-En-Jarez, France clinical trials actively recruiting patients volunteers.

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Found 18 clinical trials
Study of the Impact of a Targeted Decolonization of S. Aureus Persistent Carriers

S. aureus nasal carriage is a well-known risk factor for S. aureus infections in hemodialysis (HD) patients. Strains of carriage and infections are the same in >80% of cases We recently shown that persistent carriers of S. aureus, not intermittent ones are at increased risk of staphylococcal infections in HD. …

ARTIC42
 (2.4 away) Contact site
  • 5 views
  • 11 Feb, 2021
  • +18 other locations
Frequency and Intensity of Local Reactions in Patients Treated With 4% 5-FU vs 4% 5-FU Associated With an Emollient Cream: a Randomised Controlled Clinical Trial

Transient local skin reactions with topical Actinic Keratosis treatments such as 5-FluoroUracil (5-FU) often lead to non-adhesion from patients and thus to treatment failure. In regards to 5-FU treatment, these local reactions are related to the pharmacological action of the molecule. The current therapeutic challenge is to reduce the local …

CHU St Etienne Hopital Nord
 (2.4 away) Contact site
  • 0 views
  • 14 May, 2021
  • +23 other locations
Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis

Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by inflammatory arthritis and enthesitis involving the spine. AxSpA prevalence is around 0.17% of the French population. Tumor necrosis factor (TNF) was the first target defined in axSpA. Since one third of axSpA patients failed to the first TNF blocker, many …

biological therapy
rheumatoid arthritis
monoclonal antibodies
tumor necrosis factor
secukinumab
CHU Saint-Etienne
 (2.4 away) Contact site
  • 17 views
  • 25 Jan, 2021
  • +25 other locations
A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder

The primary objective is to evaluate the efficacy of monthly 225 mg sc fremanezumab in adult patients with migraine and major depressive disorder (MDD) The secondary objectives are to evaluate the efficacy of monthly 225 mg sc of fremanezumab in adult patients with migraine and MDD on the reduction of …

headache
body mass index
major depressive disorder
fremanezumab
depression
Teva Investigational Site 35265
 (31.6 away) Contact site
  • 360 views
  • 27 Apr, 2021
  • +64 other locations
A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

Study 20170703 is a phase 4, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of erenumab against placebo in subjects with chronic migraine (CM) who have a history of at least 1 preventive treatment failure and are diagnosed with medication overuse headache (MOH).

acute headache
botulinum toxin
hemiplegic migraine
preventive medication
experimental drug
Research Site
 (2.4 away) Contact site
  • 359 views
  • 09 Jun, 2021
  • +167 other locations
Weight-Adjusted vs Fixed Low Doses of Low Molecular Weight Heparin For Venous Thromboembolism Prevention in COVID-19

Worldwide observational studies indicate a significant prothrombogenic effect associated with SARS-CoV-2 infection with a high incidence of venous thromboembolism (VTE), notably life-threatening pulmonary embolism. According to recommendations for acute medical illnesses, all COVID-19 hospitalized patients should be given VTE prophylaxis such as a low molecular weight heparin (LMWH). A standard …

PCR test
covid-19
thromboembolism
venous thromboembolism
pneumonia
St Etienne Academic Hospital
 (2.4 away) Contact site
  • 7 views
  • 27 Jan, 2021
  • +17 other locations
Efficacy and Safety of Brodalumab Compared With Guselkumab in the Treatment of Plaque Psoriasis After Inadequate Response to Ustekinumab

The trial investigates the efficacy and safety of brodalumab against guselkumab in treatment for patients with moderate-to-severe plaque psoriasis who still have some remaining symptoms after ustekinumab treatment.

guselkumab
plaque psoriasis
ustekinumab
LEO Pharma Investigational Site
 (2.4 away) Contact site
  • 0 views
  • 02 Jun, 2021
  • +70 other locations
Comparison of Blood Pressure Control Achieved in Antihypertensive or Generic Drugs in Moderate to Severe Hypertensive Patients

Despite a large diffusion for generic anti-hypertensive, they are not currently used. Clinical validation studies could be better to convince users and prescribers than pharmacologic validation only. A pragmatic study to evaluate generic anti-hypertensive efficacy is proposed. It takes place in real conditions of care for hypertensive patients, for a …

antihypertensive drugs
hypertension
CHU de SAINT-ETIENNE
 (1.6 away) Contact site
  • 21 views
  • 11 Feb, 2021
  • +7 other locations
Evaluation of the Efficacy of Serotoninergic Antidepressants in Bulimia Nervosa According to Brain Serotonin Profile Determined by Positron Emission Tomography With [18F] MPPF.

Bulimia nervosa (BN) is a serious mental illness characterized by massive food crises followed by anxiety and compensatory behaviours (vomiting more often). Recent data show an increasing prevalence and a serious prognosis, due to excess mortality by suicide but also somatic complications. Two types of treatments are validated : serotoninergic …

anxiety
bulimia nervosa
suicide
ssri
vomiting
Chu Saint-Etienne
 (2.4 away) Contact site
  • 137 views
  • 26 Jan, 2021
  • +3 other locations
Comparison of Two Strategies of Glucocorticoid Withdrawal in Rheumatoid Arthritis Patients

The purpose of this study is to compare the proportion of patients who could withdraw from prednisone and hydrocortisone one year after a progressive decrease of GC (GC tapering) or a hydrocortisone replacement therapy in rheumatoid arthritis in remission or low disease activity.

remission
rheumatic diseases
prednisone
antirheumatics
prednisolone
Saint-Etienne Hospital
 (2.4 away) Contact site
  • 20 views
  • 11 Mar, 2021
  • +16 other locations