St Priest-En-Jarez, France Clinical Trials

A listing of St Priest-En-Jarez, France clinical trials actively recruiting patients volunteers.

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Found 17 clinical trials
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)

The purpose of the study is to determine if the combination of niraparib with Abiraterone Acetate (AA) plus prednisone compared with AA plus prednisone in participants with deleterious germline or somatic Homologous Recombination Repair (HRR) gene-mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC) provides superior efficacy in improving radiographic progression-free survival (rPFS).

Institut de Canc rologie de Loire
 (0.0 away) Contact site
  • 02 Aug, 2021
  • +397 other locations
Active Surveillance With or Without Apalutamide Treatment in Low Risk Prostate Cancer

Many prostate cancer are slow or non progressive forms that would never impair quality or quantity of like of life if undetected. For this localized prostate cancer, the recommendation is an active surveillance, however often experienced by the patient as a lack of care. Thus the introduction of new potent …

Chu Saint Etienne
 (0.9 away) Contact site
  • 23 Jan, 2021
  • +10 other locations
Efficacy of Repeat Stereotactic Radiation in Patients With Intraprostatic Tumor Recurrence

Stereo-Re-Pro aims to provide further evidence of Stereotactic Body Radiotherapy (SBRT) as a supplementary non-invasive curative treatment for local recurrence following radiotherapy. The objective of the first part of the trial (Phase I) is to select the recommended dose for salvage SBRT (either 5 x 6 Gy, 6 x 6 …

Institut de Canc rologie Lucien Neuwirth
 (0.5 away) Contact site
  • 25 Jan, 2021
  • +14 other locations
Prostate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in Hormone-sensitive Patients

INDICATION: Oligometastatic hormone-sensitive prostate cancer patients. METHODOLOGY: Open label, double arm, randomized 1:1, multicenter phase III study. PRIMARY OBJECTIVE: To assess the efficacy of ablative radiotherapy (SBRT applied to all oligometastases) administered to all gross tumor sites (metastases and prostate if applicable), in oligometastatic hormone-sensitive prostate cancer patients.

CHU Lyon Sud
 (26.5 away) Contact site
  • 18 Jun, 2021
  • +20 other locations
Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer

This is a 2x2 factorial randomized, multicenter, international, open phase III trial. The primary objective is to evaluate the benefit of acetylsalicylic acid and atorvastatin on overall survival (OS) (main endpoint) for patients with castrate-resistant prostate cancer starting first line treatment for CRPC

Institut de Canc rologie Lucien Neuwirth
 (0.5 away) Contact site
  • 01 Aug, 2021
  • +19 other locations
Erectile Dysfunction in Good Prognosis Prostate Cancer : Comparison Between Brachytherapy and Stereotactic Body Radiotherapy

The TEMPOS-GEniToUrinary Group (GETUG) study is a multicenter, randomized-controlled medico-economic study comparing brachytherapy to SBRT in low and intermediate risk prostate cancer, particularly focused on the issue of erectile dysfunction. A total of 240 potent patients are randomized in two arms. The experimental arm consists of SBRT delivering 7.25 Gy …

adenocarcinoma of prostate
Institut de Canc rologie Lucien Neuwirth
 (0.5 away) Contact site
  • 23 Jan, 2021
  • +24 other locations
Reference Curve on Bone Mineral Density in Men

In men, the hope of lower life, the absence of equivalent of menopause and the existence of a higher peak bone mass are the three factors that explain the lower incidence of osteoporosis in men.

bone densitometry
CHU de Saint Etienne
 (2.4 away) Contact site
  • 07 Mar, 2021
  • +2 other locations
Combined Apalutamide Radiotherapy and LHRH Agonist in Prostate Cancer Patients After Prostatectomy

This is a multicenter, randomized, open label, phase III study comparing the efficacy and safety of apatulamide combined with concomitant prostate-bed salvage radiotherapy (SRT) and androgen deprivation therapy (ADT) versus concomitant prostate-bed SRT and ADT in high-risk postprostatectomy biochemically relapsed prostate cancer patients.

androgen suppression
antiandrogen therapy
Centre Hospitalier Emile ROUX
 (38.2 away) Contact site
  • 26 Jan, 2021
  • +21 other locations
Comparison of Intermittent Androgen Deprivation Therapy With or Without Irradiation Recovery in Prostate Cancer Patients

Metastatic prostate cancer has traditionally been regarded as an incurable dissemination of disease, and treatment is focused on delaying progression rather than eliminating all tumor burden. Local therapies, and specifically radiotherapy, have been directed at quality of life endpoints and not at improving survival. However, advances in imaging and systemic …

androgen suppression
metastatic prostate cancer
prostate cancer metastatic
antiandrogen therapy
Centre L on B rard
 (29.5 away) Contact site
  • 23 Jan, 2021
  • +21 other locations
Physical Activity Experiment on Male Prostate Cancer Patients

Prostate cancer is the most common cancer in France (56,841 cases in 2012). Although the benefits of physical activity (PA) in cancer patients are currently well established in the scientific literature, several studies have shown that this population is not sufficiently active. Strengthen patient adherence to prevention counseling by the …

CHU Saint-Etienne
 (2.4 away) Contact site
  • 25 Feb, 2021
  • +4 other locations