Saint-Priez en Jarez, France Clinical Trials

A listing of Saint-Priez en Jarez, France clinical trials actively recruiting patients volunteers.

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Found 18 clinical trials
Study of the Impact of a Targeted Decolonization of S. Aureus Persistent Carriers

S. aureus nasal carriage is a well-known risk factor for S. aureus infections in hemodialysis (HD) patients. Strains of carriage and infections are the same in >80% of cases We recently shown that persistent carriers of S. aureus, not intermittent ones are at increased risk of staphylococcal infections in HD. …

ARTIC42
 (2.4 away) Contact site
  • 5 views
  • 18 Nov, 2020
  • +18 other locations
A Study of the Safety and Efficacy of Risankizumab in Adult Participants With Plaque Psoriasis Who Have Had a Suboptimal Response to Secukinumab or Ixekizumab

This study will evaluate whether adult participants with moderate to severe plaque psoriasis who have been treated with secukinumab or ixekizumab for at least 6 months and are experiencing a suboptimal response may benefit from switching to risankizumab with regard to skin symptoms, quality of life symptoms and psoriasis symptoms. …

ixekizumab
secukinumab
Hopital Nord /ID# 214618
 (0.5 away) Contact site
  • 49 views
  • 05 Nov, 2020
  • +63 other locations
Intensive Treatment to Reach the Target With Golimumab in ulcErative coliTis - In-TARGET

PHASE: IV TYPE OF STUDY: With direct benefit DESCRIPTIVE: multicenter, open-label, uncontrolled trial INCLUSION CRITERIA: Adults with moderate to severe ulcerative colitis who failed corticosteroids and immunosupressive therapy, or are intolerant to immunosuppressors. All included patients will be nave to anti-TNF therapy. Active disease at golimumab treatment initiation defined as …

thiopurines
asacol
corticosteroids
mesalamine
pancolitis
CHU de Saint Etienne- Hopital Nord
 (0.5 away) Contact site
  • 2 views
  • 27 May, 2019
  • +18 other locations
Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis

Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by inflammatory arthritis and enthesitis involving the spine. AxSpA prevalence is around 0.17% of the French population. Tumor necrosis factor (TNF) was the first target defined in axSpA. Since one third of axSpA patients failed to the first TNF blocker, many …

certolizumab pegol
fusion protein
anti-rheumatic drugs
DMARD
golimumab
CHU Saint-Etienne
 (2.4 away) Contact site
  • 17 views
  • 28 May, 2020
  • +24 other locations
EFFICACI : EFFicacy of Intravenous Infliximab Versus Vedolizumab After Failure of subCutaneous Anti-TNF in Patients With UlCerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that results from immune dysregulation. Arguably, the development of Tumor Necrosis Factor (TNF) antagonists (including infliximab, adalimumab and golimumab) revolutionized the management of immune-mediated chronic diseases in the past two decades. However, about one third of patients will not respond …

steroid therapy
colectomy
tumour necrosis
proctitis
golimumab
Centre Hospitalier Universitaire de Saint-Etienne
 (2.4 away) Contact site
  • 2 views
  • 10 Nov, 2019
  • +17 other locations
Comparison of Low and Intermediate Dose Low-molecular-weight Heparin to Prevent Recurrent Venous Thromboembolism in Pregnancy

This is a randomized-controlled open-label trial comparing two different doses of low-molecular-weight heparin (LMWH) in pregnant patients with a history of previous venous thromboembolism (VTE). Both doses are recommended doses in the 2012 guidelines of the American College of Chest Physicians (ACCP), but it is not known which dose is …

dalteparin
estrogen
heparin
venous thromboembolism
enoxaparin
Hopital Nord, CHU de Saint Etienne
 (2.4 away) Contact site
  • 263 views
  • 08 Jul, 2019
  • +73 other locations
A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder

The primary objective is to evaluate the efficacy of monthly 225 mg sc fremanezumab in adult patients with migraine and major depressive disorder (MDD) The secondary objectives are to evaluate the efficacy of monthly 225 mg sc of fremanezumab in adult patients with migraine and MDD on the reduction of …

depression
fremanezumab
major depressive disorder
body mass index
headache
Teva Investigational Site 35265
 (31.6 away) Contact site
  • 360 views
  • 23 Nov, 2020
  • +60 other locations
A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

Study 20170703 is a phase 4, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of erenumab against placebo in subjects with chronic migraine (CM) who have a history of at least 1 preventive treatment failure and are diagnosed with medication overuse headache (MOH).

common migraine
migraine with aura
headache
chronic migraine
erenumab
Research Site
 (2.4 away) Contact site
  • 359 views
  • 04 Nov, 2020
  • +75 other locations
Weight-Adjusted vs Fixed Low Doses of Low Molecular Weight Heparin For Venous Thromboembolism Prevention in COVID-19

Worldwide observational studies indicate a significant prothrombogenic effect associated with SARS-CoV-2 infection with a high incidence of venous thromboembolism (VTE), notably life-threatening pulmonary embolism. According to recommendations for acute medical illnesses, all COVID-19 hospitalized patients should be given VTE prophylaxis such as a low molecular weight heparin (LMWH). A standard …

heparin
venous thromboembolism
enoxaparin
pneumonia
covid-19
St Etienne Academic Hospital
 (2.4 away) Contact site
  • 7 views
  • 02 Dec, 2020
  • +17 other locations
Value of Pharmacokinetic Assays in the Prediction of Induction and Maintenance Therapeutic Response in Crohn's Disease

Vedolizumab (VDZ) is a monoclonal antibody which has shown its efficacy in Crohn's disease by inducing and maintaining clinical response/remission. The French marketing authorization was obtained for Crohn's disease in patients in failure with anti-TNF (Tumor Necrosis Factor) agents. For Crohn's disease patients treated with vedolizumab, a strong association between …

immunosuppressive agents
antibiotics
corticosteroids
mesalamine
colitis
Chu Saint Etienne
 (2.4 away) Contact site
  • 0 views
  • 26 Aug, 2020
  • +6 other locations