Saint-Priez en Jarez, France Clinical Trials

A listing of Saint-Priez en Jarez, France clinical trials actively recruiting patients volunteers.

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Found 67 clinical trials
Study of IMMU-132 in HR+/HER2- MBC (TROPICS-02)

This is an open-label, randomized, multicenter Phase 3 study to compare the efficacy and safety of Sacituzumab Govitecan versus TPC in subjects with metastatic or locally recurrent inoperable HR+/HER2- MBC, after failure of at least 2, and no more than 4, prior chemotherapy regimens for metastatic disease.

cancer chemotherapy
metastasis
eribulin
capecitabine
vinorelbine
Institut de Canc rologie Lucien Neuwirth
 (0.0 away) Contact site
  • 66 views
  • 05 Oct, 2020
  • +104 other locations
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-PD-(L) 1 agent (cohort 1) …

vinflunine
docetaxel
transitional cell carcinoma
pembrolizumab
adjuvant chemotherapy
Institut de Canc rologie de Loire
 (0.0 away) Contact site
  • 271 views
  • 12 Oct, 2020
  • +522 other locations
Double Immune Checkpoint Inhibitors in PD-L1-positive Stage IV Non-small Lung CancEr

Non Small Cell lung cancer (NSCLC) remains the first cause of death by cancer in the World. For the patients presenting a NSCLC stage IV, the median of survival is about 15 months today. The chemotherapy with platinum is the standard treatment for these patients but immunotherapy showed these efficacy …

tumor cells
ipilimumab
metastasis
gilbert's syndrome
cancer
CH Lyon Sud - Pneumologie
 (29.7 away) Contact site
  • 22 views
  • 18 Oct, 2020
  • +45 other locations
Efficacy and Safety of Nefecon in Patients With Primary IgA (Immunoglobulin A) Nephropathy

The overall aim of the study is to evaluate the efficacy, safety, and tolerability of Nefecon 16 mg per day in the treatment of patients with primary IgAN (Immunoglobulin A nephropathy) at risk of progressing to end-stage renal disease (ESRD), despite maximum tolerated treatment with renin-angiotensin system (RAS) blockade using …

Chu St Etienne-Hopital Nord, Service de Nephrologie Dialyse Transplantation renale, Av. Albert Raimond
 (0.5 away) Contact site
  • 735 views
  • 25 Oct, 2020
  • +153 other locations
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)

The purpose of the study is to determine if the combination of niraparib with Abiraterone Acetate (AA) plus prednisone compared with AA plus prednisone in participants with deleterious germline or somatic Homologous Recombination Repair (HRR) gene-mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC) provides superior efficacy in improving radiographic progression-free survival (rPFS).

Institut de Canc rologie de Loire
 (0.0 away) Contact site
  • 0 views
  • 23 Nov, 2020
  • +348 other locations
A Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

The primary objective is to assess the efficacy of nemolizumab (CD14152) compared to placebo in participants greater than or equal to (>=) 18 years of age with prurigo nodularis (PN) after a 16-week treatment period.

Galderma Investigational Site
 (2.4 away) Contact site
  • 0 views
  • 26 Nov, 2020
  • +62 other locations
Balloon to Induce Labor in Generous Women.

The rate of obesity increases continuously in France as in many developing countries.The risk of cesarean delivery is increased in obese compared to normal-weight women and postpartum complications as infections, thromboembolic events and related maternal death, are more common among obese women who deliver by cesarean than both normal-weight women …

CHU St Etienne
 (2.4 away) Contact site
  • 0 views
  • 02 Nov, 2020
  • +17 other locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

hemodynamic evaluation
macitentan 10 mg
right heart catheterization
macitentan
ventricular septal defect
Centre Hospitalier Universitaire - de Nice - Hopital Pasteur
 (186.2 away) Contact site
  • 37 views
  • 29 Nov, 2020
  • +217 other locations
REduced Dose Versus Full-dose of Direct Oral Anticoagulant After uNprOvoked Venous thromboEmbolism.

Patients with unprovoked venous thromboembolism (VTE) or VTE associated with persistent risk factors have a high risk of recurrence after stopping anticoagulation. In these patients, international guidelines recommend indefinite anticoagulation. However, prolonged use of warfarin or DOAC at therapeutic dose is associated with a significant risk of bleeding. Consequently, it …

apixaban
rivaroxaban
anticoagulants
warfarin
aspirin
CHU de Saint Etienne - H pital Nord
 (2.4 away) Contact site
  • 7 views
  • 05 Jan, 2020
  • +40 other locations
Assessment of the Efficacy Safety and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

This study will be conducted to evaluate the efficacy, safety, and tolerability of AVP-786 compared to placebo, for the treatment of agitation in participants with dementia of the Alzheimer's type.

Centre Hospitalier Universitaire de Saint- tienne - H pital Nord
 (2.4 away) Contact site
  • 379 views
  • 01 Nov, 2020
  • +220 other locations