Rouen Cedex, France Clinical Trials

A listing of Rouen Cedex, France clinical trials actively recruiting patients volunteers.

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Found 56 clinical trials
Tislelizumab in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma

The primary objective of the study is to evaluate the efficacy of tislelizumab in participants with relapsed/refractory classical Hodgkin lymphoma, as measured by the overall response rate per the Lugano Classification, and as determined by the investigator.

chemotherapy regimen
measurable disease
refractory classical hodgkin lymphoma
brentuximab
lymphoma
Centre Henri-Becquerel
 (0.3 away) Contact site
  • 0 views
  • 28 Jun, 2021
  • +41 other locations
A Study of INCMGA00012 in Metastatic Merkel Cell Carcinoma (POD1UM-201)

The purpose of this study is to assess the clinical activity and safety of INCMGA00012 in participants with advanced/metastatic Merkel cell carcinoma (MCC).

Hopital Charles Nicolle Chu Rouen H pital
 (0.4 away) Contact site
  • 21 views
  • 26 Jan, 2021
  • +117 other locations
A Safety Efficacy and Systemic Exposure Study of CD5789 Cream in Adults and Adolescents With Lamellar Ichthyosis

This is a phase 2 randomized, multi-center, double-blind, vehicle controlled, 90 day, safety, efficacy, and systemic exposure study followed by a 90 day open-label extension of trifarotene cream in adults and adolescents with autosomal recessive ichthyosis with lamellar scale.

Dermatologie p diatrique
 (69.3 away) Contact site
  • 101 views
  • 12 Mar, 2021
  • +34 other locations
Lorlatinib After Failure of First-line TKI in Patients With Advanced ROS1-positive NSCLC (ALBATROS)

ROS1 rearrangements are present in 1-2% of NSCLC cases and define a distinct molecular subgroup. Like ALK (anaplastic lymphoma kinase) rearrangements in NSCLC, ROS1 fusions confer sensitivity to the inhibitor crizotinib. Crizotinib, which is a tyrosine kinase inhibitor (TKI), has been shown to be effective in tumors in several retrospective …

Rouen - CHU
 (0.2 away) Contact site
  • 0 views
  • 07 Jun, 2021
  • +38 other locations
Pilot and Phase 2 Study of the Efficacy of a Treatment Protocol With Dexamethasone Implant Loading Dose in Patients With Diabetic Macular Edema (LOADEX)

Nowadays, steroids and anti-VEGF are the first line treatment for diabetic macular edema. Ozurdex is the most frequently used steroid and has label for both first and second line treatment. Ozurdex treatment paradigm for patients with diabetic macular edema is to inject patient only in case of huge recurrence. The …

Clinique Mathilde
 (1.2 away) Contact site
  • 0 views
  • 18 Apr, 2021
  • +19 other locations
Stereotactic Radiotherapy for Cerebral Metastases With Recent Hemorrhagic Signal

This prospective 2-stage, non-randomized Phase 2 trial evaluates the safety and efficacy of FSRT for the management of hemorrhagic brain metastases

Centre Fran ois Baclesse
 (68.4 away) Contact site
  • 10 views
  • 31 Jul, 2021
  • +4 other locations
Phase II Study of Regorafenib as Maintenance Therapy

Multicenter double-blind placebo-controlled randomized Phase II study comparing regorafenib to placebo, as maintenance therapy in metastatic soft-tissue non-adipocytic sarcomas experiencing stable disease or response after 6 cycles of doxorubicin-based chemotherapy as 1st line chemotherapy.

Centre Henri Becquerel
 (0.3 away) Contact site
  • 2 views
  • 26 Jan, 2021
  • +28 other locations
Sequences Of REGorafenib And Trifluridine/Tipiracil in Patients With Metastatic Colorectal Cancer

A randomized, phase II study comparing the sequences of regorafenib and trifluridine/tipiracil, after failure of standard therapies in patients with metastatic colorectal cancer

adenocarcinoma of colon
anticoagulants
folfox regimen
adenocarcinoma
thromboplastin
Centre Fran ois Baclesse
 (68.4 away) Contact site
  • 0 views
  • 25 May, 2021
  • +20 other locations
Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated (RB SFCE 2009)

Postoperative Treatment of Unilateral Retinoblastoma After Primary Enucleation according to histopathological risk factors of the International Retinoblastoma Staging Working Group.

cyclophosphamide
carboplatin
vincristine
thiotepa
renal function
Hopital Nord Chu Amiens
 (59.4 away) Contact site
  • 36 views
  • 24 Jan, 2021
  • +27 other locations
Impact of a Bridge Device on the Loop Ileostomy

During the creation of an ileostomy, a bridge device is systematically placed in an aim to reduce wound and peritoneal contamination by stools. Nevertheless no evidence was reported to justify this issue. Moreover the placement of a bridge device increases the difficulty of nurse cares and is associated with its …

Beauvais hospital
 (43.9 away) Contact site
  • 0 views
  • 27 Jan, 2021
  • +2 other locations