Rouen Cedex 1, France Clinical Trials

A listing of Rouen Cedex 1, France clinical trials actively recruiting patients volunteers.

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Found 331 clinical trials
VASCular Impact of Angiogenic Treatment in Patients With Advanced Colorectal Cancer

Antiangiogenic treatments are used in many tumor locations such as metastatic colorectal cancer (mCRC) with a significant improvement in carcinological results on overall survival and / or progression-free survival. However, their use is characterized by an increase in side effects and in particular cardiovascular effects such as high blood pressure …

CHU de Rouen
 (0.2 away) Contact site
  • 03 Apr, 2021
  • 1 location
Validation Study on Eye Rubbing Questionnaire in Patients With or Suspected of Having a Keratoconus (KC)

KC is a degenerative disorder of the cornea. Keratoconus etiopathogenesis remains unclear and may rely on environmental and genetic factors. Usually considered as a rare disease (<1/2000), but the prevalence is nowadays growing worldwide up to 1/500. In that pathology, cornea progressively gets thinner, and there is a deformation of …

CHU de Rouen
 (0.2 away) Contact site
  • 04 Apr, 2021
  • +6 other locations
A Study to Assess the Effects of Brolucizumab in Adult Patients With Neovascular Age Related Macular Degeneration

Neovascular age-related macular degeneration (nAMD) is characterized by the presence of choroidal neovascularization (CNV). Choroidal neovascularization consists of abnormal blood vessels originating from the choroid and can lead to hemorrhage, fluid exudation, and fibrosis, resulting in photoreceptor damage and vision loss. The safety and efficacy of brolucizumab has been demonstrated …

Novartis Investigative Site
 (62.5 away) Contact site
  • 31 May, 2021
  • +45 other locations
Comparison of Medical Results of Testicular Sperm Extraction by Conventional Surgery and Microsurgical Track

To compare motile sperm extraction rate between microTESE and conventional TESE in 18-50 years-old men with non obstructive azoospermia.

University Hospital
 (67.8 away) Contact site
  • 26 Jan, 2021
  • +5 other locations
Involvement of Monocytic B1 and B2 Receptors in Inflammation and Chronic Vascular Disease in Patients With Hereditary Bradykinetic Angioedema

The objective is to compare the gene expression of B1 and / or B2 monocyte receptors between patients with hereditary bradykinetic angioedema and control subjects.

 (0.2 away) Contact site
  • 23 Jan, 2021
  • 1 location
Clinical Evaluation of Laryngeal Transplantation: Study of 3 Patients

The experience of face and hand composite tissue transplantations reported in the international community have mainly concerned trauma patients. Feasibility and individual benefit have been demonstrated for these indications, in properly selected patients. The first laryngeal transplantation also concerned a case of post-traumatic reconstruction. A certain number of patients, who …

Service ORL & Chirurgie Cervicofaciale - H pital Charles Nicolle - CHU Rouen
 (0.2 away) Contact site
  • 10 Jun, 2021
  • +5 other locations
Evaluate the Remission MAINtenance Using Extended Administration of Prednisone in Systemic Anti-neutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis.

Immunosuppressive therapy of granulomatosis with polyangiitis (GPA, Wegener's) and microscopic polyangiitis (MPA) has transformed the outcome from death to a strong likelihood of disease control and temporary remission. However, most patients have recurrent relapses that lead to damage and require repeated treatment associated with long-term morbidity and death. Rituximab has …

CHU Amiens-H pital Nord
 (61.6 away) Contact site
  • 23 Jan, 2021
  • +57 other locations
Evaluation of the Efficacy and Safety of Hyaluronic Acid Injection in Labia Majora for Volume Restoration

DESIRIAL PLUS is a CE-marketed hyaluronic acid (since 2011) whose registered indications are moderate hypotrophy, severe hypotrophy or atrophy of the vulvar Labia Majora by subcutaneous injections. The aim is to restore volume, rehydrate and add tone and tension to connective tissue areas by filling. In this study, 71 female …

Clinique de l'Europe
 (1.2 away) Contact site
  • 25 Jan, 2021
  • +7 other locations
Comparative Evaluation of Minimally Invasive "Tibial Tuberoplasty" Surgical Technique Versus Conventional Open Surgery for Tibial Plateau Fractures

PMSI (French Medico-Administrative Database) data shows more than 10000 proximal tibial fractures diagnosed in 2014 and 4055 lateral tibial plateau fractures operated in 2013 in France. 50% of these surgical fractures is related to the lateral condyle and causes split/depression (Schatzker 2) or pure depression (Schatzker 3). This high rate …

CHU d'Amiens
 (61.6 away) Contact site
  • 18 Apr, 2021
  • +16 other locations
Impact of a Bridge Device on the Loop Ileostomy

During the creation of an ileostomy, a bridge device is systematically placed in an aim to reduce wound and peritoneal contamination by stools. Nevertheless no evidence was reported to justify this issue. Moreover the placement of a bridge device increases the difficulty of nurse cares and is associated with its …

Beauvais hospital
 (43.9 away) Contact site
  • 27 Jan, 2021
  • +2 other locations