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PARIS cedex 14, France Clinical Trials

A listing of PARIS cedex 14, France clinical trials actively recruiting patients volunteers.

RESULTS

Found (28) clinical trials

Intratumoral/Intralesional Administration of MK-4621/JetPEI With or Without Pembrolizumab in Participants With Advanced/Metastatic or Recurrent Solid Tumors (MK-4621-002)

The purpose of this study is to evaluate safety and tolerability, pharmacokinetics (PK), and preliminary antitumor activity of intratumoral (IT) / intralesional injections of MK-4621 delivered via the JetPEIin vivo linear polyethylenimine nucleic acid delivery system (MK-4621/JetPEI) as monotherapy and in combination with pembrolizumab in participants with advanced/metastatic solid tumors.

Phase

0.91 miles

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The purpose of this study is to assess the clinical activity and safety of INCMGA00012 in participants with metastatic merkel cell carcinoma (MCC).

Phase

1.56 miles

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Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus.

This is a double-blind, multi-centre, randomised, vehicle-controlled, within-subject trial. The trial is designed to establish the efficacy and safety of delgocitinib cream in the treatment of adult subjects with discoid lupus erythematosus (DLE).

Phase

1.56 miles

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Firibastat or Ramipril After Acute Myocardial Infarction for Prevention of Left Ventricular Dysfunction

At Inclusion Visit (Visit 2 [within 72 hours after acute MI]), subjects will be randomly assigned to 1 of the following 3 treatment groups in a 1:1:1 ratio: Group 1: Subjects will receive 50 mg firibastat BID for 2 weeks and then 100 mg BID for 10 weeks Group 2: ...

Phase

1.81 miles

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Pharmaco-metabolomic Effects of Statins: METASTATINE

The aim of this prospective double blind placebo-controlled study is to evaluate the acute effects of statins on microbiota and its derived metabolites at 2 and 6 weeks.

Phase

1.81 miles

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Monitoring the Antiphospholipid Syndrome:TOXicity of Drugs (APSTOX)

Several drugs and chemotherapies seem to have an impact on the immune system and are responsible of a wide range of immune side effects such as antiphospholipid syndrome. Those are poorly described, due to the modificationof the pharmacopeia, and the recent recognition of several of these adverseevents. This study investigates ...

Phase N/A

1.81 miles

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Evolution of Empathy and Emotional Intelligence During a Doctor-patient Relationship Training

Extended description of the protocol, including more technical information (as compared to the Brief Summary) if desired. Do not include the entire protocol; do not duplicate information recorded in other data elements, such as eligibility criteria or outcome measures. (Limit: 32,000 characters) Example Sudden out-of-hospital cardiac arrest (OOH-CA) remains a ...

Phase N/A

2.12 miles

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Efficacy of Non-instrumental Pleural Chest Physiotherapy

Pleural effusions are defined by an abnormal amount of fluid in the pleural space. Those complicating a pneumonia are commonly encountered in pneumology departments, and their number are increasing. If not quickly treated, complications often occur: pleural adhesions, pleural thickening which can lead to a restrictive lung disease, or even ...

Phase N/A

2.4 miles

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Safety and Efficacy of Itacitinib in Combination With Corticosteroids for Treatment of Graft-Versus-Host Disease in Pediatric Subjects

The purpose of this study is to evaluate itacitinib in combination with corticosteroids for the treatment of Grades II to IV acute graft-versus-host disease (aGVHD) in steroid-naive pediatric participants.

Phase

2.82 miles

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Diabeloop for Kids

An open-label, three-center, randomized, two-session, 4 days inpatient and 6-week follow-up home study phase, crossover study comparing Diabeloop closed-loop (CL) system and sensor-augmented pump (SAP) therapy. The follow-up home study phase will be done only in French centers for a sub study. During this session, patient wearing the closed-loop system ...

Phase N/A

2.88 miles

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