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Nanterre, France Clinical Trials

A listing of Nanterre, France clinical trials actively recruiting patients volunteers.

RESULTS

Found (23) clinical trials

Osseointegration of THA Grafted by PolyNASS (ACTISURF-CERAFIT ) Versus Non-grafted THA (CERAFIT

The infection rate after Total Hip Arthroplasty (THA) is about 1%. It is a serious condition, with high morbidity, sometimes fatal, requiring costly treatment. The treatment is difficult because "biofilm" forms very early after the bacterial contamination of the prosthesis. Prevent infection means reduce or prevent the formation of bacterial …

Phase N/A

0.39 miles

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Comparison of the 6-minute Walking Test in a Corridor and on a Non-motorized Treadmill

The Six-Minute Walk Test (6-WT) is a standardized test to assess a person's functional ability to walk as far as they can in six minutes. It is widely used in the assessment of functional disability in response to medical intervention in respiratory and cardiac conditions. This test requires a corridor …

Phase N/A

1.47 miles

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PREdiction of Chronic LUng Allograft Dysfunction

Chronic lung allograft dysfunction (CLAD) is the leading cause of long-term mortality after lung transplantation. Several risk factors for CLAD have been identified, but the exact pathophysiology and triggering molecular factors remain largely unknown. Moreover, in clinical practice, no integration of the different risk factors is achieved. CLAD is therefore …

Phase N/A

1.57 miles

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Radiotherapy of Multiple Brain Metastases Using AGuIX

The occurrence of brain metastases is a common event in the history of cancer and negatively affects the life expectancy of patients. Their incidence varies between 15 and 50% according to the histologic types. Surgery, stereotactic radiosurgery, radiotherapy and chemotherapy are the main treatments currently proposed. For patients with multiple …

Phase

3.11 miles

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WALANT Technique (Wide Awake Local Anesthesia No Tourniquet) for Carpal Tunnel Release.

This is a multicenter, prospective, randomized, open-label study assessing the interest of the association of the WALANT local infiltration technique with analgesic troncular blocks (TRONC) at the wrist, for the endoscopic CTR. This study compares two groups: CONTROL group (usual technique) : TRONC (using a long-acting LA : Ropivacaine) + …

Phase N/A

3.11 miles

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TWICE-IRI: Optimization of Second-line Therapy With Aflibercept Irinotecan (Day 1 or Day 1 3) 5-Fluorouracile and Folinic Acid in Patients With Metastatic Colorectal Cancer. A Randomized Phase III Study.

Background - Rationale Aflibercept The addition of aflibercept to the standard FOLFIRI regimen as second-line therapy was evaluated in a large phase III study (EFC10262-VELOUR). This combination significantly improved both PFS (4.7 to 6.9 months, HR=0.76; P=<0.001) and OS (12.1 to 13.5 months, HR=0.82; P=0.003). In the evaluable population (86.5%), …

Phase

3.3 miles

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Domatinostat in Combination With Avelumab in Patients With Advanced Merkel Cell Carcinoma Progressing on Anti-PD-(L)1

This phase II trial studies how well domatinostat (4SC-202) works in combination with avelumab in adult patients with advanced unresectable and/or metastatic Merkel Cell Carcinoma that have progressed on a previous therapy with an anti-PD-(L)1 antibody

Phase

3.81 miles

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Multispectral Imaging Endoscopy in Digestive Inflammation

This is a comparative, prospective, non randomized, controled, mono-centric study. Eligible patients: patients planned to undergo an upper gastrointestinal endoscopy or a rectosigmoidoscopy with biopsy in the digestive endoscopy unit of Hpital Ambroise Par. For patients accept participating to the study and sign the informed consent, they will be enrolled …

Phase N/A

4.2 miles

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Embolization of the Middle Meningeal Artery for the Prevention of Chronic Subdural Hematoma Recurrence in High Risk Patients (EMPROTECT)

Introduction: chronic SDHs are some of the most frequently encountered neurosurgical emergencies. The gold standard treatment of symptomatic chronic SDHs is burr-hole surgery followed by temporary closed system drainage. Post-operative recurrence rates may be as high as 10 to 20% and are a major source of morbidity and repeated surgery. …

Phase N/A

4.22 miles

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LOC-R01 Study of Lenalidomide and Ibrutinib in Association With Rituximab-Methotrexate Procarbazine Vincristin (R-MPV)

The objective of this proposal is to test the feasibility and efficacy of two targeted induction chemotherapies obtained by adding either Lenalidomide or Ibrutinib to a standard Rituximab-High Dose (HD) Methotrexate (MTX) based induction chemotherapy regimen. The R-MPV regimen is chosen as the backbone chemotherapy because of its wide use …

Phase

6.23 miles

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