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Montpellier Cedex 5, France Clinical Trials

A listing of Montpellier Cedex 5, France clinical trials actively recruiting patients volunteers.

RESULTS

Found (398) clinical trials

A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies

This is a global, multicenter, open-label safety extension study. Participants receiving single-agent trastuzumab emtansine or trastuzumab emtansine administered in combination with other agents in a Genentech/Roche-sponsored parent study who are active and deriving benefit at the closure of parent study are eligible for continued treatment in this study.

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Breast-Conserving Surgery Techniques in Treating Women With Breast Cancer

OBJECTIVES: Primary - Evaluate the percentage of histologically healthy margins maintained during resection in women with breast cancer. Secondary - Evaluate local recurrence at 5 years. - Evaluate aesthetic results. - Evaluate quality of life using the QLQC30 and BR23 questionnaires. OUTLINE: This is a multicenter study. Patients undergo oncoplastic ...

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Epoetin Beta in Patients Undergoing Chemotherapy for Solid Tumors

OBJECTIVES: Primary - Identify factors predictive of treatment failure in patients with solid tumors treated with epoetin beta while undergoing chemotherapy. Secondary - Evaluate the impact of achieving target hemoglobin levels (i.e., hemoglobin > 11 g/dL) after 8 weeks of treatment with epoetin beta. - Evaluate changes in hemoglobin levels ...

Phase N/A

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Usefulness of Anticoagulant Treatment in First Isolated Symptomatic Calf Vein Thrombosis

This study will compare the evolution of the infrapopliteal DVT into two groups of patients, one treated with LMWH (Nadroparine) + elastic compression during 6 weeks and the second one treated with a placebo + elastic compression during 6 weeks. Patients will be assigned to intervention groups by chance, and ...

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Sunitinib as First-Line Therapy in Treating Patients With Locally Advanced Metastatic Papillary Renal Cell Cancer

OBJECTIVES: Primary - To determine the objective tumor response rate in patients with locally advanced or metastatic papillary renal cell carcinoma treated with sunitinib malate. Secondary - To evaluate the safety of this drug in these patients. - To determine time-to-event variables of overall survival, time to disease progression, time ...

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Radiation Therapy Chemotherapy and Cetuximab Followed by Surgery Chemotherapy and Cetuximab in Treating Patients With Locally Advanced or Metastatic Rectal Cancer That Can Be Removed by Surgery

OBJECTIVES: Primary - Determine the complete remission rate at 6 months after neoadjuvant radiotherapy, capecitabine, and oxaliplatin (XELOX), and cetuximab followed by surgery, adjuvant FOLFOX 4, and cetuximab in patients with synchronous locally advanced or metastatic cancer of the rectum with resectable metastases (T3-4 Nx or T2 N+ M1). Secondary ...

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Capecitabine Irinotecan and Oxaliplatin in Treating Patients With Metastatic Cancer

OBJECTIVES: Primary - Determine the maximum tolerated dose and dose-limiting toxicities of capecitabine. Secondary - Determine the recommended phase II dose of capecitabine. - Define the toxicity profile. - Evaluate potential antitumor activity in terms of objective response, duration of response, and time to disease progression. - Evaluate the pharmacokinetic ...

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Fluorouracil Cisplatin Cetuximab and Radiation Therapy in Treating Patients With Esophageal Cancer That Can Be Removed by Surgery

OBJECTIVES: Primary - To determine the maximum tolerated dose of fluorouracil and cisplatin when administered with cetuximab concurrently with esophageal radiotherapy. (Phase I) - To determine the complete histological response rate (after surgical resection). (Phase II) Secondary - To determine progression-free survival and overall survival. (Phase II) - To determine ...

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Identification of Cardiovascular Risk Factors Linked to Renal Failure Progression

The aim of this study is to appreciate the relationship between: - extension of coronary calcifications and chronic renal failure progression - extension of coronary calcifications and levels of osteoprotegerin (bone disease marker) - cardiovascular risk factors and coronary calcifications - cardiovascular risk factors and existence of cardiovascular diseases

Phase N/A

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Biological Factors in Predicting Response to Treatment in Patients With Esophageal Cancer or Rectal Cancer

OBJECTIVES: Primary - Analyze various biological factors that can be used as markers to predict response to treatment and correlate with the signaling pathway of EGFR. Secondary - Establish a tissue bank to store information about the response to treatment and survival. OUTLINE: Patients undergo endoscopy, 11 biopsies of tumor ...

Phase N/A

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