Lille, France Clinical Trials

A listing of Lille, France clinical trials actively recruiting patients volunteers.

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Found 753 clinical trials
Pembrolizumab Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

This is a randomized, double-blind, study that compares pembrolizumab with placebo given as adjuvant therapy in participants with high-risk locally advanced cutaneous squamous cell carcinoma (LA cSCC) that have undergone surgery with curative intent in combination with radiotherapy. The primary hypothesis is that pembrolizumab is superior to placebo in increasing …

mk-3475
adjuvant therapy
cancer
pembrolizumab
CHRU de Lille - Hopital Claude Huriez ( Site 0355)
 (1.9 away) Contact site
  • 69 views
  • 29 Jul, 2021
  • +146 other locations
Tislelizumab in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Carcinoma

This is a randomized (1:1), double-blind, placebo-controlled, Phase 3 study designed to compare the efficacy and safety of tislelizumab or placebo plus chemotherapy as first-line (1L) therapy for locally advanced unresectable or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma.

Institut Hospitalier Franco-Britannique
 (124.3 away) Contact site
  • 38 views
  • 25 Jan, 2021
  • +193 other locations
Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS

The primary objective of the trial is to confirm the efficacy of glepaglutide in reducing parenteral support volume in patients with short bowel syndrome. Glepaglutide is the International Nonproprietary Name and USAN for ZP1848.

H pital Erasme
 (58.4 away) Contact site
  • 85 views
  • 05 May, 2021
  • +92 other locations
Long-term Safety Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

The purpose of this study is to collect long-term safety, tolerability, effectiveness and health outcomes data in eligible subjects who have participated in a Novartis ofatumumab clinical MS study. Vaccination sub-study The purpose of this research sub-study is to find out the effects of ofatumumab on the development of antibody …

tetanus
ofatumumab
pneumococcal conjugate vaccine
Novartis Investigative Site
 (41.8 away) Contact site
  • 234 views
  • 16 May, 2021
  • +260 other locations
A Study to Evaluate the Safety Tolerability and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis

This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS) and to assess the pharmacokinetics (PK) of BIIB017 in pediatric participants with RRMS in Part 1. In Part 2, the study will evaluate the long-term safety of BIIB017 and further …

magnetic resonance imaging brain
relapsing multiple sclerosis
interferon
Research Site
 (1.9 away) Contact site
  • 109 views
  • 27 Jul, 2021
  • +71 other locations
Study of Sasanlimab (PF-06801591) in Combination With Bacillus Calmette-Guerin (BCG) in Participants With High-Risk Non-Muscle Invasive Bladder Cancer

CREST: Combination of sasanlimab and alternative BCG Regimens to Evaluate outcomes with Subcutaneous anti-PD-1 Treatment Phase 3 Design with 3 study Arms (A, B and C). Arms A and B consists of two study drugs, PF-06801591 plus BCG. Arm C consists of one study drug, BCG. The study is designed …

Centre d'oncologie Bourgogne
 (1.2 away) Contact site
  • 10 views
  • 07 Jul, 2021
  • +216 other locations
Investigating Safety Tolerability Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours

A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents with solid tumours.

Research Site
 (1.2 away) Contact site
  • 16 views
  • 28 Jul, 2021
  • +19 other locations
A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adult Participants With Moderate to Severe Ulcerative Colitis

This phase 2b study is designed to have all subjects go into a 12 week induction period to compare different doses of study drug against placebo. After induction is complete all subjects will receive active therapy for 40 weeks, followed by a 12 week follow up period.

CHU d'Amiens-Picardie - SITE SUD
 (60.7 away) Contact site
  • 32 views
  • 30 Jul, 2021
  • +248 other locations
adaptatiVe Endovascular Strategy to the CloT MRI in Large Intracranial Vessel Occlusion

In the VECTOR trial, the aim is to analyze, in case of SVS+ occlusions, a first line Embotrap II added to CA combined strategy compare to CA alone strategy. Many practitioners are convinced that a first line strategy with CA alone is easy, safe, rapid and efficient. Maybe, after two, …

CHU Amiens-Picardie
 (60.7 away) Contact site
  • 0 views
  • 24 Jun, 2021
  • +28 other locations
Study of Cabozantinib as 2nd Line Treatment in Subjects With Locally Advanced or Metastatic Renal Cell Carcinoma (RCC) With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors

The overall objective of this study is to evaluate the efficacy and safety of cabozantinib as 2nd line treatment in subjects with unresectable, locally advanced or metastatic RCC with a clear-cell component, who progressed after prior Checkpoint Inhibitors (CPI) therapy with ipilimumab and nivolumab in combination or CPI combined with …

H pital priv Le Bois
 (1.2 away) Contact site
  • 2 views
  • 28 Jul, 2021
  • +77 other locations