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Juvisy sur Orge, France Clinical Trials

A listing of Juvisy sur Orge, France clinical trials actively recruiting patients volunteers.

RESULTS

Found (14) clinical trials

IDentification of Factors Predictive of Tofacitinib's Survival in Patient With Rheumatoid Arthritis

This is an observational, open-label, prospective, multi-centre, national study designed to evaluate the factors predictive of Tofacitinib's survival in patients with rheumatoid arthritis If catastrophisation is described as a distortion of the perception of pain involving a both emotional and cognitive component, pushing the patient to see only the worst, ...

Phase N/A

0.0 miles

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Intratumoral/Intralesional Administration of MK-4621/JetPEI With or Without Pembrolizumab in Participants With Advanced/Metastatic or Recurrent Solid Tumors (MK-4621-002)

The purpose of this study is to evaluate safety and tolerability, pharmacokinetics (PK), and preliminary antitumor activity of intratumoral (IT) / intralesional injections of MK-4621 delivered via the JetPEIin vivo linear polyethylenimine nucleic acid delivery system (MK-4621/JetPEI) as monotherapy and in combination with pembrolizumab in participants with advanced/metastatic solid tumors.

Phase

6.87 miles

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ANgiogenic Function at NOrmal TErm on Placenta

The objective of this study is to better understand the regulation of trophoblast expression of pro- and antiangiogenic factors such as placenta growth factor (PlGF) or Soluble FMS like tyrosin-kinase-1 (sFlt-1), and more particularly on human differentiated trophoblastic cells from "healthy" placentas. The measurement of the variation in gene and ...

Phase N/A

7.72 miles

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Safety and Efficacy of Emixustat in Stargardt Disease

The purpose of this study is to determine if emixustat hydrochloride reduces the rate of progression of macular atrophy compared to placebo in subjects with Stargardt disease.

Phase

7.72 miles

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Determinants of Frailty Among of Informal Caregivers of Demented Patient

Frailty, a transitional state between successful and pathological aging, may be benefit from early multi-interventional intervention. Fried's criteria are the more commonly used criteria to diagnose frailty : Loss of weight > 4.5 kg over one year, Self-reported exhaustion, Low muscle strength (handgrip <20% norm for age and sex), Low ...

Phase N/A

7.72 miles

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Comparison of Two Methods for Assessing Cough Capacity in Intensive Care Unit After Cardiac Surgery

Weaning from mechanical ventilation represents 50% of the time spent under mechanical ventilation (1). The risk factors identified in the failure to wean from mechanical ventilation are: left heart dysfunction with LVEF < 30%. an ineffective cough presence of resuscitation neuromyopathy mechanical ventilation time >7 days presence of a delirium ...

Phase N/A

7.8 miles

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A Study of Imlifidase in Patients With Guillain-Barr Syndrome

This is an open-label, single arm, multi-centre, phase II study of imlifidase in combination with standard care IVIg in patients with GBS. The study will recruit up to 30 patients who are eligible for IVIg treatment based on current practice (i.e. GBS disability score >3 and within 10 days of ...

Phase

8.09 miles

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Firibastat or Ramipril After Acute Myocardial Infarction for Prevention of Left Ventricular Dysfunction

At Inclusion Visit (Visit 2 [within 72 hours after acute MI]), subjects will be randomly assigned to 1 of the following 3 treatment groups in a 1:1:1 ratio: Group 1: Subjects will receive 50 mg firibastat BID for 2 weeks and then 100 mg BID for 10 weeks Group 2: ...

Phase

9.62 miles

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Pharmaco-metabolomic Effects of Statins: METASTATINE

The aim of this prospective double blind placebo-controlled study is to evaluate the acute effects of statins on microbiota and its derived metabolites at 2 and 6 weeks.

Phase

9.62 miles

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Monitoring the Antiphospholipid Syndrome:TOXicity of Drugs (APSTOX)

Several drugs and chemotherapies seem to have an impact on the immune system and are responsible of a wide range of immune side effects such as antiphospholipid syndrome. Those are poorly described, due to the modificationof the pharmacopeia, and the recent recognition of several of these adverseevents. This study investigates ...

Phase N/A

9.62 miles

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