Epargny Metz-Tessy, France Clinical Trials

A listing of Epargny Metz-Tessy, France clinical trials actively recruiting patients volunteers.

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Found 18 clinical trials
Preoperative Stereotactic Radiosurgery for Brain Metastases

STEP is a French multicentre, prospective, non-randomized, phase II study designed to assess 6-months local control after pre-operative stereotactic radiosurgery (SRS) for patients with brain metastases

Centre Hospitalier d'Annecy-Genevois
 (0.6 away) Contact site
  • 0 views
  • 15 Aug, 2021
  • +7 other locations
Preemptive Therapy for High Risk Chronic Lymphoid Leukemia Stage A

Open label, single arm, multicenter phase II trial.

lymphoid leukemia
venetoclax
beta human chorionic gonadotrophin
lymphocytosis
gilbert's syndrome
Ch Annecy
 (3.2 away) Contact site
  • 14 views
  • 09 Jul, 2021
  • +23 other locations
PONAZA : A COMBINATION OF PONATINIB AND 5-AZACITIDINE IN CHRONIC MYELOGENOUS LEUKAEMIA IN ACCELERATED PHASE OR IN MYELOID BLAST CRISIS

This project is strategy aiming to improve the survival of patients with chronic myelogenous leukemia in advanced phase and myeloid blast crisis. The basis of this strategy is to add the demethylating agent 5-Azacitidine to the tyrosine kinase inhibitor ponatinib and evaluate its activity in 2 cohorts of patients with …

Centre Hospitalier Annecy Genevois
 (1.6 away) Contact site
  • 1 views
  • 25 Jan, 2021
  • +25 other locations
Safety and Efficacy of Ponatinib Followed by Imatinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase

The investigators hypothesize that, in newly diagnosed de novo chronic phase CML patients, an induction treatment with ponatinib for 6 months should increase the rate of patients reaching a stable MR4.5 allowing cessation of imatinib treatment. The investigators proposal is to conduct a multicenter, Phase II trial to evaluate the …

imatinib
anagrelide
hydroxyurea
philadelphia chromosome
dasatinib
Centre Hospitalier Annecy-Genevois
 (3.3 away) Contact site
  • 0 views
  • 22 Jul, 2021
  • +34 other locations
Impact of Pegfilgrastim on Trastuzumab Anti-tumor Effect and ADCC in Operable HER2+ Breast Cancer Breast Cancer

First preclinical data suggest that pegfilgrastim could constitute a potent adjuvant for immunotherapy with mAb possessing ADCC/ADCP properties as trastuzumab. Combined treatment of pegfilgrastim and trastuzumab should translate into an increased rate of pathological clinical response. Therefore the investigators' proposal is to evaluate the clinical and biological impact of pegfilgrastim …

platelet count
neutrophil count
breast cancer staging
paclitaxel
trastuzumab
Centre Hospitalier Annecy Genevois
 (1.6 away) Contact site
  • 8 views
  • 12 Sep, 2021
  • +12 other locations
Denosumab and Nivolumab Combination as 2d-line Therapy in Stage IV NSC Lung Cancer With Bone Metastases (DENIVOS)

Bone metastases are common in Non-Small Cell Lung Cancer (NSCLC). They most often occur during disease progression. It is thought that more than half of the patients with bone metastases will have at least 1 skeletal-related event (SRE, i.e. pathological fractures, medullary compression, analgesic radiotherapy, preventive and/or analgesic surgery and …

tumor cells
neutrophil count
stage iv non-small cell lung cancer
squamous cell carcinoma
bone scan
CH Annecy-Genevois
 (1.6 away) Contact site
  • 102 views
  • 25 Jan, 2021
  • +42 other locations
COlchicine for Left VEntricular Remodeling Treatment in Acute Myocardial Infarction

Inflammatory processes have been identified as key mediators of ischemia/ reperfusion injury in ST-segment elevation myocardial infarction. They add additional damage to the myocardium and are associated with clinical adverse events (heart failure and cardiovascular death) and poor myocardial recovery. All the different anti-inflammatory approaches to reduce reperfusion injury have …

percutaneous coronary intervention
ischemia
stemi
left bundle branch block
st elevation myocardial infarction
Centre Hospitalier d'Annecy
 (3.2 away) Contact site
  • 3 views
  • 24 May, 2021
  • +14 other locations
Study of Pixantrone in CD20+ Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma

This study will evaluate the efficacy of Pixantrone with rituximab, ifosfamide and etoposide as measured by the overall metabolic response rate after 2 cycles of treatment or at permanent treatment discontinuation.

Centre Hospitalier Annecy Genevois
 (1.6 away) Contact site
  • 7 views
  • 14 May, 2021
  • +26 other locations