Clermont Ferrand cedex 01, France Clinical Trials

A listing of Clermont Ferrand cedex 01, France clinical trials actively recruiting patients volunteers.

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Found 457 clinical trials
Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with confirmed VTE. This study is designed to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of edoxaban and to compare the efficacy and safety of edoxaban against standard of care in …

venous thromboembolism
heparin therapy
edoxaban
vitamin k antagonist
anticoagulants
CHU Clermont Ferrand - H pital d'Estaing
 (1.2 away) Contact site
  • 0 views
  • 28 Jan, 2021
  • +169 other locations
Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or S zary Syndrome (SS)

The purpose of this study is to determine whether resminostat will be able to delay or prevent worsening of disease in patients with advanced stage mycosis fungoides or Szary Syndrome that have recently achieved disease control with previous systemic therapy.

interferon
resminostat
chemotherapy regimen
mycosis
maintenance treatment
Centre Hospitalier Lyon-Sud
 (84.0 away) Contact site
  • 898 views
  • 01 Aug, 2021
  • +91 other locations
Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients

The purpose of the study is to evaluate efficacy and safety of Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-Edotreotide compared to targeted molecular therapy with Everolimus in patients with inoperable, progressive, somatostatin receptor-positive (SSTR+), neuroendocrine tumours of gastroenteric or pancreatic origin (GEP-NET).

everolimus
edotreotide
radionuclide therapy
measurable disease
progressive disease
Hospices civils de Lyon
 (87.7 away) Contact site
  • 220 views
  • 19 Apr, 2021
  • +82 other locations
A Comparative Study of 2 Doses of BM Autologous H-MSC+Biomaterial vs Iliac Crest AutoGraft for Bone Healing in Non-Union

ORTHOUNION is a multi-centre, open, comparative, randomized, clinical trial with three parallel arms that aims to compare the efficacy of three treatments to enhance bone healing in patients with long bone non-union.

Department of Orthopaedic Surgery, CHU Tours
 (159.0 away) Contact site
  • 20 views
  • 23 Jan, 2021
  • +18 other locations
Study to Assess Efficacy and Safety of Cx601 Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)

The purpose of this study is to evaluate the combined remission of complex perianal fistulas, defined as the clinical assessment at Week 24 of closure of all treated external openings that were draining at baseline despite gentle finger compression, and absence of collections greater than (>) 2 centimeter (cm) (in …

endoscopy
luminal
ulceration
certolizumab pegol
methotrexate
CHU de Clermont-Ferrand - Estaing
 (1.2 away) Contact site
  • 202 views
  • 28 May, 2021
  • +177 other locations
COsegregation of VARiants in the BRCA1/2 and PALB2 Genes

The aim of the COVAR project is to classify reliably a maximum of VUS of the French database in order to use them for the genetic counseling. The results obtained through this study will have a major impact on clinical management of the patients and their families conducting in some …

KIT
breast cancer
BRCA1
BRCA2
palb2
Centre Jean Perrin
 (1.4 away) Contact site
  • 16 views
  • 26 Jan, 2021
  • +76 other locations
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

The ALL SCTped 2012 FORUM is a multinational, multi-centre, controlled, prospective phase III study for the therapy and therapy optimisation for children and adolescents with ALL in complete morphological remission (CR, less than 5% bone marrow blasts, no blasts in cerebrospinal fluid, no other extramedullary leukemia), who have an indication …

transplant conditioning
thiotepa
fludarabine
thymoglobulin
busulfan
IHOP / Lyon, Service H matologie et d'Oncologie p diatrique
 (84.0 away) Contact site
  • 389 views
  • 25 Jan, 2021
  • +157 other locations
REduced Dose Versus Full-dose of Direct Oral Anticoagulant After uNprOvoked Venous thromboEmbolism.

Patients with unprovoked venous thromboembolism (VTE) or VTE associated with persistent risk factors have a high risk of recurrence after stopping anticoagulation. In these patients, international guidelines recommend indefinite anticoagulation. However, prolonged use of warfarin or DOAC at therapeutic dose is associated with a significant risk of bleeding. Consequently, it …

warfarin
apixaban
aspirin
anticoagulation therapy
anticoagulants
CHU de Clermont Ferrand - H pital Gabriel Montpied
 (1.3 away) Contact site
  • 7 views
  • 27 Jan, 2021
  • +58 other locations
Randomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over

Colorectal cancer occurs mainly in elderly patients. Recent estimation showed that in France more than 50% of the patients diagnosed with a colorectal cancer are 70 years old or more. Adjuvant chemotherapy has demonstrated a benefit on disease-free survival and overall survival after a stage III colon cancer resection. Nevertheless …

cancer
primary tumor
capecitabine
colon cancer
oxaliplatin
Institut de Canc rologie Lucien Neuwirth
 (65.2 away) Contact site
  • 31 views
  • 24 Jan, 2021
  • +202 other locations
Community-Acquired Pneumonia : Evaluation of Corticosteroids

Mortality of severe Community-Acquired Pneumonia (CAP) has not declined over time and is between 25 and 30% in sub-groups of patients. Corticosteroids (CTx) could down-regulate pulmonary and systemic inflammation, accelerate clinical resolution and decrease the rate of inflammation-associated systemic complications. Two recent meta-analyses suggest a positive effect on severe CAP …

antibiotic therapy
antibiotics
cough
purulent sputum
corticosteroids
Service de R animation M dicale Polyvalente, H pital G Montpied
 (2.1 away) Contact site
  • 4 views
  • 25 May, 2021
  • +64 other locations