Clermont Ferrand cedex 01, France Clinical Trials

A listing of Clermont Ferrand cedex 01, France clinical trials actively recruiting patients volunteers.

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Found 461 clinical trials
A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine

The main purpose of this study is to evaluate the efficacy and safety of galcanezumab for the preventive treatment of chronic migraine in participants 12 to 17 years of age. The primary objective is to demonstrate the superiority of galcanezumab versus placebo in the reduction of monthly migraine headache days …

APHM H pital de la Timone
 (204.2 away) Contact site
  • 13 Jun, 2021
  • +75 other locations
Atogepant for Prophylaxis of Migraine in Participants Who Failed Previous Oral Prophylactic Treatments.

This study will assess the safety, tolerability, and efficacy of Atogepant 60 mg compared with placebo in episodic migraines in participants who previously failed 2 to 4 classes of oral prophylactic treatments.

CHU Gabriel Montpied
 (1.6 away) Contact site
  • 12 Jun, 2021
  • +134 other locations
Eradication of Residual Disease by Preemptive Immunointervention After Allogeneic Hematopoietic Stem Cells Transplantation in Chronic Lymphocytic Leukemia

Usually Chronic lymphocytic leukemia (CLL) is a disease of the elderly patients. However, the diagnosis in young patients become more frequently with poor prognosis. The identification of new prognostic factors permits early determination of the high risk population and provide them the therapeutic intensification. Allogeneic transplantation of hematopoietic stem cells …

graft versus host disease
cell transplantation
residual tumor
  • 07 Nov, 2020
  • 1 location
Vitrification and Slow Freezing for Cryopreservation of Blastocyst

Improvement in the treatment of infertility by Assisted Reproductive Techniques (ART) allows single embryo transfer to be applied without compromising pregnancy rates after the first in vitro fertilization (IVF) or Intra Cytoplasmic Sperm Injection (ICSI) attempt in women less than 36 years old with good embryo quality. The policy of …

embryo transfer
in vitro fertilization
reproductive techniques
single embryo transfers
embryo culture
  • 07 Nov, 2020
  • 1 location
Evaluation of Botulinum Toxin Injection Efficacy in the Treatment of Head Essential Tremor

Essential head tremor (HT) does not usually respond to drug treatment such as propranolol or primidone or to surgical treatment such as deep brain stimulation of the thalamic ventralis intermedius nucleus. Botulinum toxin (Btx) is widely used and efficient in the treatment of blepharospasm and cervical dystonia. Btx prevents the …

H pital neurologique
 (84.0 away) Contact site
  • 23 Jan, 2021
  • +16 other locations
Allogeneic Hematopoietic Stem Cell Transplantation

To assess the engraftment of hematopoietic stem cells following reduced-intensity conditioning in children presenting with solid tumors or hematological malignancy by evaluating post-transplantation chimerism and hematological reconstitution. To study acute and/or chronic graft-versus-host reaction (incidence and severity) and immune reconstitution, post-transplantation To study the effectiveness of the protocol on tumor …

myeloablative conditioning
solid tumor
  • 07 Nov, 2020
  • 1 location
Per-Operative Radiotherapy by Papillon +TM in Localized Breast Cancer

Phase II study; open recruitment, multicentrique. The aim of this clinical research is to evaluate faisability and toxicity of the per-operative radiotherapy using PAPILLON + TM device for localized breast cancers patients over 65 years.

Centre Antoine Lacassagne
 (249.1 away) Contact site
  • 04 Jun, 2021
  • +1 other locations
Lorlatinib After Failure of First-line TKI in Patients With Advanced ROS1-positive NSCLC (ALBATROS)

ROS1 rearrangements are present in 1-2% of NSCLC cases and define a distinct molecular subgroup. Like ALK (anaplastic lymphoma kinase) rearrangements in NSCLC, ROS1 fusions confer sensitivity to the inhibitor crizotinib. Crizotinib, which is a tyrosine kinase inhibitor (TKI), has been shown to be effective in tumors in several retrospective …

Clermont-Ferrand - CHU
 (1.3 away) Contact site
  • 07 Jun, 2021
  • +38 other locations
Food Matrices Based on Fruit Pastes as Vectors of Carbohydrates for the Prevention and Management of Protein-energy Undernutrition in the Elderly (Fruisenior)

To develop more natural fruit pastes matrices that can effectively act as carbohydrate vectors in the elderly population and that are part of a normal diet while maintaining the pleasure of eating.

  • 15 Jun, 2021
  • 1 location
Efficacy of Repeat Stereotactic Radiation in Patients With Intraprostatic Tumor Recurrence

Stereo-Re-Pro aims to provide further evidence of Stereotactic Body Radiotherapy (SBRT) as a supplementary non-invasive curative treatment for local recurrence following radiotherapy. The objective of the first part of the trial (Phase I) is to select the recommended dose for salvage SBRT (either 5 x 6 Gy, 6 x 6 …

Institut de Canc rologie Lucien Neuwirth
 (65.2 away) Contact site
  • 25 Jan, 2021
  • +14 other locations