Clermont Ferrand cedex 01, France Clinical Trials

A listing of Clermont Ferrand cedex 01, France clinical trials actively recruiting patients volunteers.

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Found 456 clinical trials
A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine

The main purpose of this study is to evaluate the efficacy and safety of galcanezumab for the preventive treatment of chronic migraine in participants 12 to 17 years of age. The primary objective is to demonstrate the superiority of galcanezumab versus placebo in the reduction of monthly migraine headache days …

APHM H pital de la Timone
 (204.2 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +78 other locations
Atogepant for Prophylaxis of Migraine in Participants Who Failed Previous Oral Prophylactic Treatments.

This study will assess the safety, tolerability, and efficacy of Atogepant 60 mg compared with placebo in episodic migraines in participants who previously failed 2 to 4 classes of oral prophylactic treatments.

CHU Gabriel Montpied
 (1.6 away) Contact site
  • 0 views
  • 19 Jul, 2021
  • +134 other locations
Double Immune Checkpoint Inhibitors in PD-L1-positive Stage IV Non-small Lung CancEr

Non Small Cell lung cancer (NSCLC) remains the first cause of death by cancer in the World. For the patients presenting a NSCLC stage IV, the median of survival is about 15 months today. The chemotherapy with platinum is the standard treatment for these patients but immunotherapy showed these efficacy …

nivolumab
pd-l1
cancer
metastasis
tumor cells
Clermont Ferrand - CHU
 (1.6 away) Contact site
  • 22 views
  • 25 Jan, 2021
  • +45 other locations
An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma

The overall aim of this project is to improve the outcome of patients diagnosed with ependymoma by improving and harmonising the staging and the standard of care of this patient population and to improve the investigators understanding of the underlying biology thereby informing future treatment. The program will evaluate new …

CHU Clermont- Ferrand - H pital Estaing
 (2.1 away) Contact site
  • 25 views
  • 24 Jan, 2021
  • +61 other locations
Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: My Own Specific Treatment

The MOST Plus study is a two-period phase II clinical trial, conducted in patients with all types of progressive solid tumors after at least 1 prior systemic treatment regimen for advanced disease (in the absence of a validated second line therapy). The main goal of this study is to evaluate …

Centre Jean Perrin
 (1.4 away) Contact site
  • 0 views
  • 11 Feb, 2021
  • +11 other locations
Familial Dysglobulinemia

Multiple Myeloma (MM) is a malignant proliferation of monoclonal plasma cells. Myeloma accounts for almost 14% of all hematologic cancers and is essentially incurable. Myeloma commonly evolves from a precursor disease, Monoclonal gammopathy of undetermined significance (MGUS). Despite intensive study, the etiology of MGUS and myeloma are unknown and no …

D partement d'H matologie l'Institut de Canc rologie de la Loire
 (65.2 away) Contact site
  • 26 views
  • 25 Jan, 2021
  • +46 other locations
Pembrolizumab Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

This is a randomized, double-blind, study that compares pembrolizumab with placebo given as adjuvant therapy in participants with high-risk locally advanced cutaneous squamous cell carcinoma (LA cSCC) that have undergone surgery with curative intent in combination with radiotherapy. The primary hypothesis is that pembrolizumab is superior to placebo in increasing …

pembrolizumab
cancer
adjuvant therapy
mk-3475
CH Lyon Sud Hospices Civils de Lyon ( Site 0350)
 (83.6 away) Contact site
  • 69 views
  • 01 Aug, 2021
  • +146 other locations
Trial of Andexanet in ICH Patients Receiving an Oral FXa Inhibitor

Randomized, controlled clinical trial evaluating the efficacy and safety of andexanet versus usual standard of care in patients with intracranial hemorrhage anticoagulated with a direct oral anticoagulant

CHU Edouard Herriot, Anaesthesia-resuscitation
 (84.0 away) Contact site
  • 19 views
  • 17 Jul, 2021
  • +180 other locations
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-programmed death ligand 1(PD-[L]1) agent …

adjuvant chemotherapy
pembrolizumab
advanced urothelial carcinoma
renal function
transitional cell carcinoma
Centre Jean Perrin
 (1.4 away) Contact site
  • 271 views
  • 01 Aug, 2021
  • +592 other locations
Impact of a PCT(Procalcitonin) Rapid Test -Based Approach on ATB (Antibiotics) Use in Children With Fever Without Source

Because a newly available point-of-care test may have real interest especially for children in the Emergency Department (ED) setting, by limiting painful and stressful venipunctures and decreasing the length of stay in the ED, the investigators hypothesize that integrating this new capillary Procalcitonin (PCT) rapid test in the DIAFEVER CPR …

Chu Saint Etienne
 (66.8 away) Contact site
  • 14 views
  • 25 Jan, 2021
  • +27 other locations