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Casetelnau le Lez, France Clinical Trials

A listing of Casetelnau le Lez, France clinical trials actively recruiting patients volunteers.

RESULTS

Found (437) clinical trials

Activity and Safety Study of BKM120 in Monotherapy in Patient With Metastatic Head and Neck Cancer Recurrent or Progressive

BKM120 is a PI3K inhibitor. The PI3K/Protein kinase B (AKT) signalling pathway deregulation is frequently observed in Head and neck cancer. In addition to its role in tumor genesis, the PI3K/AKT pathway seems to be involved in resistance to cetuximab. In this context, the study proposal is to evaluate the ...

Phase

1.85 miles

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Comparison FOLFIRINOX Panitumumab vs mFOLFOX6 Panitumumab in RAS/B-RAF Wild-type Metastatic Colorectal Cancer Patients

PRIMARY OBJECTIVE: Evaluation of complete response rate on treatment combining FOLFIRINOX and panitumumab SECONDARY OBJECTIVE(S): Overall Survival Progression free survival Secondary resection Early tumor shrinkage (ETS) Depth of response (DpR) Safety profile (NCI CTCAE v 4.03 classification) Diagnostic performance of ccfDNA analysis compared to the tumor-tissue analysis (current gold standard)

Phase

1.85 miles

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Influence of Intestinal Microbiota Implantation in Preterm Infants on Microbiota and Immune Orientation at 3 Years

The secondary objectives are to study the links between changes of the intestinal microbiota premature infants in terms of: changing diversity of the microbiota in the first 6 weeks of life; changes in the bacterial community (UniFrac study) during the first 6 weeks of life; diversity of the microbiota up ...

Phase N/A

1.85 miles

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Effect of Intratumoral Injection of Gene Therapy for Locally Advanced Pancreatic Cancer

Pancreatic adenocarcinoma is the fifth leading cause of cancer related deaths in Western countries. The sole curative treatment is surgical resection. Unfortunately, curative surgery is possible in only 10 to 15 % of cases. In a palliative way, the remaining patients can be treated with chemotherapy in locally advanced (Gemcitabine) ...

Phase

1.85 miles

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Binge Eating Disorder and Obesity : Functional MRI Study

The aim of this functional neuroimaging study is to analyze brain responses to visual food cues in obese (body mass index > 97th percentile) adolescents with BED (according to the criteria Marcus and Kalarchian) compared with healthy control adolescents in two situations : hunger et satiety. Fifteen obese adolescents (12/16 ...

Phase N/A

1.85 miles

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Comparative Efficacy Study of Titratable Versus Active Mandibular Advancement Splint in Sleep Apnea

Sleep apnea is a common disorder that occurs in 3-10 % of the adult population. This disorder disrupts the architecture and quality of sleep. Continuous positive airway pressure (CPAP) therapy is the standard treatment, but in some cases, it can not be used (patient refusal or intolerance). In these cases, ...

Phase N/A

1.85 miles

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Assessment of the "Appui Parental": A Program of Early Support to Parenthood

Objective: the main objective of this study is to determine the efficiency of Appui Parental program by evaluating its impact on the development of children aged from 0 to 3 years. The secondary objectives are to study the effects of the intervention on: the mother-child interactions, the degree of therapeutic ...

Phase N/A

1.85 miles

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Efficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)

Gastrointestinal stromal tumours (GISTs) are rare mesenchymal neoplasms, mostly diagnosed between 55 and 60 years of age, which account for 5% of all sarcomas. Worldwide annual incidence is approximately 12 cases per million people, corresponding to approximately 800 new cases per year in France. A large majority of GISTs harbour ...

Phase

1.85 miles

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MEMENTO-VAScular COmponents of Dementia

Alzheimer's disease (AD) is a neurodegenerative disorder thought to be caused by the accumulation of the peptide amyloid beta and the hyperphosphorylated tau protein in the brain. There are increasing arguments in favor of an important role of vascular damages in the development and progression of AD. The time course ...

Phase N/A

1.85 miles

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Double Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLC

The purpose of this study is to find out whether it is better to receive a new drug, MEDI4736, or better to receive no further treatment after surgery (and possibly chemotherapy) for lung cancer.

Phase

1.85 miles

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