Casetelnau le Lez, France Clinical Trials

A listing of Casetelnau le Lez, France clinical trials actively recruiting patients volunteers.

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Found 622 clinical trials
Respiratory Drive in Patients With Univentricular Congenital Heart Disease

The aim is to evaluate the correlation between the respiratory control to hypercapnia at rest and the VE/VCO2 slope measured during cardiopulmonary exercise testing. The hypothesis is that patient with univentricular congenital heart disease have a increasing of respiratory drive like chronic heart failure. This increasing of respiratory drive could …

Institut Saint-Pierre
 (7.4 away) Contact site
  • 23 Jan, 2021
  • 1 location
A Trial COmparing staNdard of Care Versus Treat to Target With telemonitoRing and Patient Education in Patients With Ulcerative cOlitis Initiating Adalimumab

PHASE: IV DESCRIPTIVE: Randomized, interventional, open label multicenter trial POPULATION: Moderate to severe ulcerative colitis STUDY TREATMENTS: Patients will all receive Adalimumab 160/80/40mg EOW until V1 (W14) followed by 40mg EOW until V2 (W26) and could be optimized up to 80mg EOW (or 40 EW according to patient and/or investigator …

CHU Montpellier - H pital Saint Eloi
 (7.5 away) Contact site
  • 02 Jun, 2021
  • +34 other locations
Cost-utility Study of a Group of Compensatory Cognitive Remediation in Schizophrenia

Significant cognitive impairment (executive functions, memory, attention) is common in schizophrenia affecting up to 80% of patients. But pharmacological treatments (typical and atypical antipsychotic) do not have impact on cognitive functioning. For over 20 years, alternative non-pharmacological therapeutics have been developed in schizophrenia. These techniques called cognitive remediation specifically target …

cognitive remediation
cognitive impairment
cognitive deficits
typical antipsychotic
cognitive training
Montpellier University Hospital
 (7.5 away) Contact site
  • 28 Jan, 2021
  • +9 other locations
Mouth Opening Prevention Education Nutrition (OPEN)

In France, 11 316 new cases of upper aero-digestive tract cancer were estimated in 2012. These cancers are treated with a triple-therapy combining surgery, radiotherapy and chemotherapy/targeted therapies. Treatment-induced sequelae are often burdensome: reduction in mouth opening, eventually on to trismus, limitation of lips and tongue mobility, deterioration in oral …

squamous cell carcinoma
dental caries
Centre Regional de Lutte Contre le Cancer - Centre Val d'Aurelle
 (1.9 away) Contact site
  • 24 Jan, 2021
  • +6 other locations
A Clinicobiological Database in Metastatic Digestive Cancers

Creation of a collection of blood samples that will be collected before and then under treatment in patients with digestive adenocarcinoma during the 1st and 2nd metastatic line and which, depending on scientific progress, can be used for research projects aimed at developing tailored patient management strategies.

gastrointestinal cancer
adenocarcinoma of the colon
Institut r gional du cancer de Montpellier
 (1.9 away) Contact site
  • 25 Jan, 2021
  • +1 other locations
Efficacy of Intradiscal Injection of BM-MSC in Subjects With Chronic Low Back Pain (LBP) Due to Lumbar Degenerative Disc Disease (DDD) Unresponsive

This will be a multicenter, prospective, double blind, randomized phase 2/3 trial comparing culture-expanded allogeneic adult BM-MSCs with sham-treated controls. This trial will evaluate the efficacy of intradiscal injection of BM-MSCs in chronic low back pain due to lumbar degenerative disc disease (DDD) unresponsive to conventional therapy . Visual analog …

back pain
intervertebral disc degeneration
conservative management
low back pain
UH Montpellier
 (7.5 away) Contact site
  • 24 Jan, 2021
  • +2 other locations
Microglial Activation in Narcolepsy Type 1 and Kleine-Levin Syndrome: Positron Emission Tomography (PET) Study in [18F] DPA-714

Type 1 narcolepsy (NT1) is a chronic sleep disorder caused by the selective and irreversible loss of neurons from the hypothalamus, which synthesizes a neurotransmitter: hypocretin (Hcrt) / orexin. The exact cause of this destruction is still unknown, but the autoimmune hypothesis is strongly favored, involving the interaction of genetic …

University Hospital of Montpellier
 (1.9 away) Contact site
  • 25 Jan, 2021
  • 1 location
PD-1 Inhibitors and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer

Overall survival (OS) of patients with advanced (stage IIIB/IV) non-small-cell lung cancer (NSCLC) remains short after the first line of treatment with a median OS of 12.2 months in non squamous NSCLC and 9.2 months in squamous NSCLC . In this setting the programmed death 1/ligand 1 (PD-1/-L1) were targeted …

cancer chemotherapy
measurable disease
Centre de canc rologie du grand Montpellier-Clinique Clementville
 (1.9 away) Contact site
  • 25 Jan, 2021
  • +8 other locations
Evaluation of the Nonmotor Symptomatology of Parkinsonian Patients Treated With Two Strategies Related to Apomorphine Pump Therapy in French Hospitals

There is currently no consensus on the adequate concomitant treatment to apomorphine pump in Parkinson's disease (PD). In practice, some centers withdraw all dopaminergic agonists when initiating apomorphine pump therapy, whereas others combine the two. To date, there has been no study led to determine the best strategy for efficiently …

motor symptoms
dopamine agonists
H pital Gui de Chauliac
 (7.5 away) Contact site
  • 24 Jan, 2021
  • +9 other locations
CT Air-trapping for the Early Identification of Benralizumab Responders Among Eosinophilic Asthma Patients

BenraliScan aims to obtain thoracic computed tomography imaging data to predict the future level of patient response to a monoclonal antibody. Because the clinical responses under study can take many months to manifest, early identification of patients most-likely to benefit from treatment and treatment rule-out for others will save considerable …

other asthma
forced expiratory volume
University Hospitals of Montpellier
 (1.9 away) Contact site
  • 26 Jan, 2021
  • +1 other locations