Caen cedex, France Clinical Trials

A listing of Caen cedex, France clinical trials actively recruiting patients volunteers.

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Found 11 clinical trials
Investigation of Radium-223 Dichloride (Xofigo) a Treatment That Gives Off Radiation That Helps Kill Cancer Cells Compared to a Treatment That Inactivates Hormones (New Antihormonal Therapy NAH) in Patients With Prostate Cancer That Has Spread to the Bone Getting Worse on or After Earlier NAH

Researchers in this study want to compare how well drug radium-223 dichloride (Xofigo) and new (novel) anti-hormonal (NAH) therapy work in participants with prostate gland cancer which has spread to the bone and progressed on or after one line of NAH therapy. Meanwhile researchers want to compare the safety of …

Centre Eug ne Marquis - Rennes Cedex
 (93.4 away) Contact site
  • 09 Jun, 2021
  • +144 other locations
Multicenter Randomized Two-arms Study Evaluating the BK Viral Clearance in Kidney Transplant Recipients With BK Viremia.

BK virus nephropathy (BKVN), a consequence of the strong immunosuppressive therapy given after kidney transplantation, represents a growing problem in the kidney transplant (KT) setting. In recent cohorts, BKVN concerns up to 10% of kidney transplant recipients and early signs of BK virus (BKV) infection as development of asymptomatic viruria …

CHU C te de Nacre
 (0.8 away) Contact site
  • 23 Jan, 2021
  • +9 other locations
Oral Anticoagulation in Haemodialysis Patients

Guidelines recommend oral anticoagulation with vitamin K antagonists for atrial fibrillation whenever the CHADS2VASC score is superior or equal to 2. As there are no specific guidelines for the hemodialysis patients with atrial fibrillation, the general guidelines apply. However, several retrospective studies suggest that these patients do not benefit from …

Service de N phrologie
 (64.1 away) Contact site
  • 25 Jan, 2021
  • +38 other locations
Phone-based Safety Monitoring of Baclofen Prescriptions for Alcohol Use Disorder

BACLOPHONE is a prospective multicenter cohort study, conducted in two nearby French regions (Hauts-de-France and Normandie). BACLOPHONE consists of the monthly phone-based monitoring of 792 patients during their first year of baclofen prescription for alcohol use disorder. The main objective of the study is to determine the rate of patients …

psychotropic drugs
University Hospital of Rouen
 (68.4 away) Contact site
  • 24 Jan, 2021
  • +18 other locations
Cognition and HRQoL in Adults With Highly-active RMS in Year 3 and 4 After Initial Mavenclad Dose (CLARIFY MS Extension)

The purpose of the study is the evaluation of the effect of a treatment for highly-active relapsing multiple sclerosis (RMS). This is the extension study to CLARIFY MS (NCT03369665), to assess cognitive impairment and health related quality of life (HRQoL) in participants with highly active RMS, at 4 years after …

relapsing multiple sclerosis
Centre Universitaire de Rouen
 (68.4 away) Contact site
  • 04 Jun, 2021
  • +62 other locations
Identification of New Immune Factors Specific of Relapse in Childhood B Lineage Acute Lymphoblastic Leukemia

B-acute lymphoblastic leukaemia (ALL) is the most common childhood malignancy. Despite enhancement of childhood B-ALL outcome, relapses remain difficult to treat. Several studies in adult acute myeloid leukaemia have shown that proliferation of immunosuppressive cells -particularly T regulatory (Treg) cells and deficient natural killer (NK) cells- was associated with poor …

b acute lymphoblastic leukemia
immunosuppressive agents
childhood all
University Hospital of Reims
 (92.0 away) Contact site
  • 23 Jan, 2021
  • +18 other locations
EFFICACI : EFFicacy of Intravenous Infliximab Versus Vedolizumab After Failure of subCutaneous Anti-TNF in Patients With UlCerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that results from immune dysregulation. Arguably, the development of Tumor Necrosis Factor (TNF) antagonists (including infliximab, adalimumab and golimumab) revolutionized the management of immune-mediated chronic diseases in the past two decades. However, about one third of patients will not respond …

tumour necrosis
tumor necrosis factor alpha
Centre Hospitalier de Saint-Malo
 (82.2 away) Contact site
  • 26 Jan, 2021
  • +23 other locations
Comparison of Two Strategies for the Management of Atrial Fibrillation After Cardiac Surgery

Postoperative atrial fibrillation is a common complication after cardiac surgery with a rate of 30%. However, management of postoperative atrial fibrillation is controversial. Two strategies are recommended : heart rate control using a betablocker or rhythm control with amiodarone. Landiolol is a new-generation beta-blocker with a short half-life, which was …

coronary artery bypass graft
heart surgery
beta-adrenergic blocking agents
Caen University Hospital
 (0.8 away) Contact site
  • 23 Jan, 2021
  • 1 location
Initiation of First-line Antiretroviral Treatment With TENOFOVIR ALAFENAMIDE - EMTRICITABINE - BICTEGRAVIR at the First Clinical Contact in France: Trial IMEA 055 - FAST

Evaluation of antiretroviral treatment adherence using determination of Bictegravir, Emtricitabine and Tenofovir with new HIV patients in France

Hopital Raymond Poincare
 (117.9 away) Contact site
  • 24 Jan, 2021
  • +15 other locations
A Trial COmparing staNdard of Care Versus Treat to Target With telemonitoRing and Patient Education in Patients With Ulcerative cOlitis Initiating Adalimumab

PHASE: IV DESCRIPTIVE: Randomized, interventional, open label multicenter trial POPULATION: Moderate to severe ulcerative colitis STUDY TREATMENTS: Patients will all receive Adalimumab 160/80/40mg EOW until V1 (W14) followed by 40mg EOW until V2 (W26) and could be optimized up to 80mg EOW (or 40 EW according to patient and/or investigator …

anti-tnf-alpha therapy
CHU Rennes H pital Pontchaillou
 (94.4 away) Contact site
  • 02 Jun, 2021
  • +34 other locations