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Caen cedex, France Clinical Trials

A listing of Caen cedex, France clinical trials actively recruiting patients volunteers.

RESULTS

Found (176) clinical trials

Study of Predictive Factors of Progression of Motor Neurone Disease

This is a prospective observational multicentric French study of a cohort of 1000 ALS patients, 100 neurological controls and 200 healthy controls followed from the first signs to the end of the disease. The aim of the present study is therefore to determine the clinical, biological, imaging, and electrophysiological biomarkers …

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Multi-modal Neuroimaging in Alzheimer's Disease

The three main objectives of this project are: To Identify, compare and combine the predictive markers of AD, To better understand the pathophysiologic mechanisms of AD, To study the ability of different neuroimaging techniques to monitor AD's evolution. For these purposes, detailed neuropsychological evaluations, biological measures and brain structural & …

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Follow-up of a National Cohort of Melanoma Stage IV and Unresectable Stage III Patients

Melanoma is the first cancer in terms of increasing frequency in France. Prevention can be efficient in detecting melanoma with good prognosis but mortality remains unchanged and 15 to 20% of patients still die from melanoma. Indeed metastatic melanoma is a heterogeneous highly and multiple mutations driven cancer which is …

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UroCCR Database: French Research Network for Kidney Cancer

The UroCCR database is a national medico-scientific network focused on therapeutic management and applied research in kidney cancer. Secondary objectives: - Evaluate and compare different surgical approaches in the treatment of kidney cancer, - Evaluate and compare safety/efficacy of different drugs in the treatment of kidney cancer.

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Study of the Effect of the Benfluorex

More than 5 million persons in France exposed, in last years, to the taking of the Benfluorex. Arisen, at certain patients, of a valvulopathy characterized by mitrals and/or aortic leaks Withdrawal of the French market: nov. 2009 Only a percentage limited by exposed patients developed a severe valvulopathy (1/1000), whereas …

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Assessment of Attentional and Executive Disorders in Multiple Sclerosis Using Techniques of Virtual Reality

Since many years cognitive disorders are a main topic of clinical research in Multiple Sclerosis (MS) as there could be observed early on in the disease and could induce with time in patients significant socio-professional burden. Today assessment of cognitive dysfunction in MS is still based on traditional pencil-paper task …

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National Register of Oesophageal Atresia

The esophageal atresia is a group of birth defects including a break in continuity of the esophagus with or without persistent communication with the trachea (tracheoesophageal fistula), sometimes associated (from 50%) of other malformations (heart, kidney, digestive ...). The current prognosis for this ailment is good. However he persists a …

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SArcopenia Mobility PHYsical Activity and Post-operative Risk of Bladder Carcinoma in the Elderly

Sarcopenia is associated with lower prognosis in solid tumors, but this has not been studied in bladder carcinoma requiring cystectomy. According to EWGSOP recommendations, the diagnosis of sarcopenia is based on walking speed, grip strength and muscle mass. These three elements can easily be measured (specially muscle mass measurement by …

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Mucormycosis in ICU

Mucormycosis is an invasive fungal infection affecting patients with various clinical conditions especially patients with heavy immunosuppression or patients with trauma or extensive burns. The incidence of Mucormycosis is currently increasing reaching 7% of invasive fungal infections in some immunocompromised patients. Because of its aggressive nature, Mucormycosis is associated with …

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Observatoire Des Patients Atteints de Laminopathies et Emerinopathies (Observatory for PAtients With Laminopathies and Emerinopathies)

Laminopathies and emerinopathies are complex group of rare disorders due to mutations in A-type lamins (LMNA) and Emerin (EMD) genes. Among them, disorders affecting skeletal and/or cardiac muscles are the most frequent clinical manifestations, with cardiac disease being a major cause of death. Remarkable progress has been made in the …

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