CORBEIL-ESSONNES Cedex, France Clinical Trials

A listing of CORBEIL-ESSONNES Cedex, France clinical trials actively recruiting patients volunteers.

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Found 91 clinical trials
Familial Dysglobulinemia

Multiple Myeloma (MM) is a malignant proliferation of monoclonal plasma cells. Myeloma accounts for almost 14% of all hematologic cancers and is essentially incurable. Myeloma commonly evolves from a precursor disease, Monoclonal gammopathy of undetermined significance (MGUS). Despite intensive study, the etiology of MGUS and myeloma are unknown and no …

H pital Sud Francilien
 (0.0 away) Contact site
  • 25 Jan, 2021
  • +46 other locations
Extra Hospital Delivery Outside Medical Presence.

The purpose of this study is to prospectively evaluate a standardized procedure of medical regulation based on a validated predictive score of eminent delivery (SPIA) in comparison with usual inhomogeneous practices. This standardized procedure impacting the process of care production (when receiving the call for regulation for unannounced delivery) would …

Centre Hospitalier Marc Jacquet
 (9.5 away) Contact site
  • 01 May, 2021
  • +28 other locations
Late Clinical Events Associated With COVID-19 Infection

Several publications document the occurrence of symptoms that persist or occur late. The identification of the observed clinical manifestations and their clinical and paraclinical description are essential to better understand the natural evolution of COVID-19, to clarify the pathophysiological mechanism of these possible late manifestations, and to identify potential management …

CH Melun Marc Jacquet
 (9.5 away) Contact site
  • 05 Feb, 2021
  • +9 other locations
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-programmed death ligand 1(PD-[L]1) agent …

advanced urothelial carcinoma
transitional cell carcinoma
adjuvant chemotherapy
Centre de radioth rapie et d'Oncologie m dicale de l'Essonne
 (3.8 away) Contact site
  • 03 Jun, 2021
  • +587 other locations
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)

The purpose of the study is to determine if the combination of niraparib with Abiraterone Acetate (AA) plus prednisone compared with AA plus prednisone in participants with deleterious germline or somatic Homologous Recombination Repair (HRR) gene-mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC) provides superior efficacy in improving radiographic progression-free survival (rPFS).

Centre de radioth rapie et d'Oncologie m dicale de l'Essonne
 (3.8 away) Contact site
  • 02 Jun, 2021
  • +394 other locations
CAMOVID : Evaluation of Efficacy and Safety of Camostat Mesylate for the Treatment of SARS-CoV-2 Infection - COVID-19 in Ambulatory Adult Patients

The overall objective of the study is to determine the therapeutic effect and tolerance of Camostat mesylate, compared to placebo in adult patients with ambulatory COVID-19 disease, presenting with risk factors of severe COVID-19. Camostat mesylate is a serine protease TMPRSS2 (Transmembrane Serine Protease 2) inhibitor which has been successfully …

Centre Hospitalier Sud Ile de France - Melun
 (9.5 away) Contact site
  • 14 Apr, 2021
  • +4 other locations
Efficacy and Tolerance of Telerobotic vs Standard Ultrasound Exam in Children

In children with Covid-19, the diagnosis of Kawasaki Disease (KD) and pneumonia should be made very quickly. However, the regional hospitals surrounding Paris don't have the required expertise. The use of MELODY allows the paediatric team to quickly carry out the necessary examinations while avoiding the movement of patients and …

CHI Villeneuve-Saint-Georges
 (8.4 away) Contact site
  • 30 May, 2021
  • +1 other locations
Medical Economic Evaluation of Bilateral Allograft of Hands and Forearms

The double amputation of the forearms is a rare handicap that seriously impacts the autonomy and the quality of life of patients, social and familial exclusion, and dependence on third parties for everyday activities. The management of these patients is nearly exclusively through the use of prostheses. Certain patients refuse …

Service de R ducation et appareillage - Institut Robert Merle d'Aubign
 (9.7 away) Contact site
  • 15 Jun, 2021
  • +11 other locations
Effect of L. Reuteri on Bowel Movements in Children (BIOWELL Study)

A randomized, multicenter, placebo-controlled, double blind study in two parallel groups testing the efficacy of daily oral supplementation with the probiotic L.reuteri DSM17938 compared to placebo in increasing the number of spontaneous bowel movements in infants and children with functional constipation.

functional constipation
CH Sud francilien
 (0.0 away) Contact site
  • 07 May, 2021
  • +8 other locations
First Line Metastatic Pancreatic Cancer : 5FU/LV+Nal-IRI Gemcitabine+Nab-paclitaxel or a Sequential Regimen of 2 Months 5FU/LV+Nal-IRI

In Europe, pancreatic cancer (PC) is the 7th most common cancer and the 5th leading cause of cancer death in Europe. Each year, the number of deaths due to prostate cancer is almost as high as the number of new cases diagnosed reflecting the poor prognosis associated with this disease. …

measurable disease
platelet count
adjuvant chemotherapy
CH Sud Francilien
 (0.0 away) Contact site
  • 22 Jan, 2021
  • +47 other locations