Angers Cedex 2, France Clinical Trials

A listing of Angers Cedex 2, France clinical trials actively recruiting patients volunteers.

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Found 405 clinical trials
Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL

Participants in this study will have diffuse large B-cell lymphoma (DLBCL) that has come back or not gotten better with treatment. The trial will study whether brentuximab vedotin plus two drugs works better to treat this type of cancer than the two drugs alone. Patients will be randomly assigned to …

b-cell lymphoma
Center Hospitalier Universitaire d' Angers
 (0.7 away) Contact site
  • 27 Sep, 2021
  • +80 other locations
Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss

The purpose of this study is to determine whether treatment with alpelisib in combination with nab-paclitaxel is safe and effective in subjects with advanced triple negative breast cancer (aTNBC) who carry either a PIK3CA mutation (Study Part A) or have PTEN loss (Study Part B1) or PTEN loss without PIK3CA …

breast cancer
Novartis Investigative Site
 (0.9 away) Contact site
  • 20 Sep, 2021
  • +153 other locations
Trial of COVID-19 Outpatient Treatment in Individuals With Risk Factors for Aggravation

In adults with COVID-19 without criteria for hospitalization or oxygen therapy but with risk factors for aggravation, early treatment may avoid hospitalization, indication for oxygen therapy or death. No treatment is currently validated for this indication.

nasopharyngeal swab
Universit Angers
 (0.7 away) Contact site
  • 09 Aug, 2021
  • +9 other locations
Genome Sequencing Strategies for Genetics Diagnosis of Patients With Intellectual Disability

Introduction : Intellectual Disability (ID) is the most common cause of referral in the pediatric genetic centers and is characterized by an extreme genetic heterogeneity corresponding to a myriad of rare diseases that complicates the identification of ID's. Overall today in France, for non-syndromic ID affected patients, the Fra-X detection, …

CHU d'Angers
 (0.0 away) Contact site
  • 02 Sep, 2021
  • +13 other locations
Thromboembolic Risk Stratification by TRiP(Cast) Score to Guide Physicians in Preventive Treatment Prescriptions for Patients With Lower Limb Trauma Requiring Brace or castING.

Non-surgical traumas to the lower limbs that require orthopedic immobilisation (plaster or splint) are a frequent reason for going to accident and emergency. Due to venous stasis caused by immobilisation, hypercoagulable states and vascular injuries brought on by the trauma, these patients are at risk of developing VTE. For this …

CHU Angers
 (0.7 away) Contact site
  • 05 Mar, 2021
  • +12 other locations
Study to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined With Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for Recurrence

The main purpose of this study is to compare the efficacy of bempegaldesleukin plus nivolumab versus nivolumab in patients with completely resected Stage IIIA/B/C/D, or Stage IV cutaneous melanoma who are at high risk for recurrence.

malignant melanoma of skin
metastatic cutaneous melanoma
immunologic adjuvant
Investigator Site - Site #2437
 (0.7 away) Contact site
  • 16 Sep, 2021
  • +247 other locations
Safety Tolerability Pharmacokinetics and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics, and early clinical activity of INCB099280 in participants with select solid tumors

solid tumour
solid tumors
Institut de Cancerologie de L Ouest - Site Paul Papin
 (0.7 away) Contact site
  • 11 Sep, 2021
  • +17 other locations
This Study Collects Information on the Safety of Inhaled Pegylated Adrenomedullin (PEG-ADM) How the Drug is Tolerated and How it Affects Patients Suffering From a Type of Lung Failure That Cause Fluid to Build up in the Lungs Making Breathing Difficult (ARDS)

The study is composed of two parts. In part A of the study two active doses of inhaled pegylated adrenomedullin (PEG-ADM) will be compared regarding safety and efficacy to a substance that has no therapeutic effect (placebo) in order to find an optimal and safe of the study drug. In …

positive end expiratory pressure
assisted ventilation
Centre Hospitalier Universitaire - Angers
 (0.7 away) Contact site
  • 05 Sep, 2021
  • +40 other locations
Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen

TREOCAPA is a Phase II/III European Multicentre study concerning the prophylactic treatment by Acetaminophen of extremely preterm infant during the first five days after birth. The Phase II is a dose finding phase in order to assess the minimum effective dose regimen of acetaminophen for the closure of PDA for …

CHU Angers
 (2.7 away) Contact site
  • 01 Jul, 2021
  • +22 other locations
Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer

The aim of this study is to provide darolutamide treatment to patients who participated in a previous study with darolutamide supported by Bayer and the treating doctor considers that the continuation of the treatment with darolutamide to be beneficial. Patients will be carried over from the previous studies and continue …

Centre Hospitalier Universitaire - Angers
 (0.0 away) Contact site
  • 04 Sep, 2021
  • +302 other locations